Colorectal News and Research

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Saudi Arabia lags in CRC screening despite high awareness of early detection benefits

According to the statistics of the Saudi National Cancer Registry issued by the Saudi Health Council for 2020, colorectal cancer (CRC) is ranked second among types of cancer, and first in men and third in women accounting for 12.3% with 1729 cases among all registered cancer cases.

30 May 2024

New weapon against cancer: "DNA warhead" targets mutant protein in tumor cells

Tumor protein P53 (TP53) plays an important role in suppressing the growth of tumors. Mutations in the gene for TP53 can have a disastrous effect, hampering the body's ability to fight tumors and even encouraging their growth.

29 May 2024

Researchers overturn the prevailing theory for colorectal tumor initiation

Research led by Weill Cornell Medicine provides new evidence that most colorectal cancers begin with the loss of intestinal stem cells, even before cancer-causing genetic alterations appear.

29 May 2024

Abdominal pain and hematochezia could be crucial red flags for early-onset colorectal cancer

The study identifies key symptoms like abdominal pain and hematochezia as significant indicators of early-onset colorectal cancer and stresses the importance of early diagnosis to improve survival rates.

28 May 2024

New paper reveals the broad potential of TNIK as a therapeutic target for some aging-related diseases

A new paper in Trends in Pharmacological Sciences from researchers at generative artificial intelligence (AI)- and robotics-powered clinical stage drug discovery company Insilico Medicine ("Insilico") and ETH Zurich reveals the broad potential of TNIK as a therapeutic target for some of the most pervasive aging-related diseases, including fibrosis, cancer, obesity, and Alzheimer's.

28 May 2024

Study reveals pivotal role of the circadian clock in enhancing checkpoint inhibitor cancer therapy

A multidisciplinary research team at the University of California, Irvine has revealed that the circadian clock – the biological pacemaker that governs daily rhythms in physiological processes, including immune functions – can be leveraged to enhance the efficacy of checkpoint inhibitor cancer therapy.

28 May 2024

Study suggests broccoli may reduce cancer risk

A meta-analysis of over 730,000 individuals indicates that high broccoli consumption is linked to lower cancer prevalence, though more robust research is needed to confirm its chemopreventive properties.

27 May 2024

Immunotherapy-chemotherapy combo boosts survival for patients with metastatic colorectal cancer

A study led by UCLA Health Jonsson Comprehensive Cancer Center researchers found that using a combination of experimental immunotherapy drugs with chemotherapy significantly improves progression-free survival and overall survival for patients with metastatic colorectal cancer who have previously undergone standard chemotherapy treatment when compared to those who received the targeted therapy regorafenib alone.

24 May 2024

Physician-pharmacy integration not associated with change in the care of cancer patients

Integration of pharmacies with physician practices, where on-site pharmacies open at physician practice locations, is a growing trend in cancer treatment.

23 May 2024

New AI model sets benchmark in digital pathology with superior cancer diagnostics

Researchers developed Prov-GigaPath, a whole-slide pathology foundation model using a novel vision transformer architecture. The model demonstrates superior performance in mutation prediction, cancer subtyping, and vision-language tasks. It leverages large-scale real-world data from over 30,000 patients to enhance clinical diagnostics.

23 May 2024

New study reveals how genes can alter the cancer-fighting power of fruits and fiber

A study in eBioMedicine uncovers two genetic loci that modify the impact of fiber and fruit intake on colorectal cancer risk, highlighting gene-diet interactions.

22 May 2024

Latest advances in gastric cancer and other cancer-related studies to be presented at DDW 2024

Cancer-related studies, including a diagnostic tool for gastric cancer and trends in gallbladder and colorectal cancers, will be presented this week at Digestive Disease Week (DDW) 2024.

21 May 2024

Low-fat diets significantly reduce lung cancer risk in older adults, study finds

Study found that adhering to low-fat diets significantly reduces lung cancer risk in older adults, with the most substantial benefits observed in current smokers. High consumption of saturated fats was linked to increased lung cancer risk, particularly for small-cell lung cancer.

20 May 2024

Proteins in the blood could warn people of cancer more than seven years before it is diagnosed

Researchers from the UK investigated associations between 1,463 plasma proteins and 19 cancers, using observational and genetic approaches in participants of the UK Biobank.

17 May 2024

Study reveals no survival benefit from systemic therapy in very advanced solid tumors

Patients with very advanced solid tumors saw no significant improvement in overall survival after receiving systemic therapy, according to a study published today in JAMA Oncology by researchers at The University of Texas MD Anderson Cancer Center and Yale Cancer Center.

17 May 2024

Plant-based diets reduce cancer and heart disease risks, study shows

Study reveals that plant-based diets significantly reduce the risks of cancer and cardiometabolic diseases while improving overall health markers.

16 May 2024

Offering screening options boosts colorectal cancer test rates

The rate of colorectal cancer screenings more than doubled when patients were given a choice between which type of screening they wanted-;a take-home kit or colonoscopy-;compared to those who were only offered the colonoscopy, according to new research led by the Perelman School of Medicine at the University of Pennsylvania.

16 May 2024

Study reveals latest cancer trends in Canada

The number of cancer cases and deaths in Canada is expected to increase because of a growing and aging population, but the overall rates of people being diagnosed with and dying from cancer will continue to decline, according to the latest cancer trends research in CMAJ.

13 May 2024

Mainz Biomed to unveil breakthrough early cancer detection study results at DDW 2024

Mainz Biomed N.V., a molecular genetics diagnostic company specializing in the early detection of cancer, will present an analysis from its eAArly DETECT study at Digestive Disease Week (DDW) 2024 in Washington D.C. from May 18th to May 21st. DDW is recognized as a premier forum for the latest advancements in gastroenterology, hepatology, endoscopy, and gastrointestinal surgery.

11 May 2024

Study shows steep rise in colorectal cancer among younger populations

Colorectal cancer incidence has steadily increased among younger people in the U.S. over the last two decades, with the youngest seeing the most dramatic jumps, according to a study scheduled for presentation at Digestive Disease Week (DDW) 2024.

9 May 2024

Colorectal News and Research

Saudi Arabia lags in CRC screening despite high awareness of early detection benefits

New weapon against cancer: "DNA warhead" targets mutant protein in tumor cells

Researchers overturn the prevailing theory for colorectal tumor initiation

Abdominal pain and hematochezia could be crucial red flags for early-onset colorectal cancer

New paper reveals the broad potential of TNIK as a therapeutic target for some aging-related diseases

Study reveals pivotal role of the circadian clock in enhancing checkpoint inhibitor cancer therapy

Study suggests broccoli may reduce cancer risk

Immunotherapy-chemotherapy combo boosts survival for patients with metastatic colorectal cancer

Physician-pharmacy integration not associated with change in the care of cancer patients

New AI model sets benchmark in digital pathology with superior cancer diagnostics

New study reveals how genes can alter the cancer-fighting power of fruits and fiber

Latest advances in gastric cancer and other cancer-related studies to be presented at DDW 2024

Low-fat diets significantly reduce lung cancer risk in older adults, study finds

Proteins in the blood could warn people of cancer more than seven years before it is diagnosed

Study reveals no survival benefit from systemic therapy in very advanced solid tumors

Plant-based diets reduce cancer and heart disease risks, study shows

Offering screening options boosts colorectal cancer test rates

Study reveals latest cancer trends in Canada

Mainz Biomed to unveil breakthrough early cancer detection study results at DDW 2024

Study shows steep rise in colorectal cancer among younger populations

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