Molecule News and Research

RSS

Novel drug molecule offers hope for early Parkinson's disease treatment

A novel drug molecule could potentially lead to new treatments to prevent Parkinson's disease in younger patients, according to new research.

20 Sep 2024

Childhood adversity linked to elevated health risks, differing by sex and stress

Researchers assess the heterogeneous effects of childhood adversity on disease biomarkers and health conditions in adulthood.

20 Sep 2024

Hypothalamic ECM remodeling drives insulin resistance, contributing to obesity and diabetes

Researchers have discovered that remodeling of extracellular matrix (ECM) in the hypothalamus, specifically around AgRP neurons, drives insulin resistance and metabolic disease. Disrupting this ECM buildup improves insulin sensitivity and may be a promising treatment for obesity and diabetes.

19 Sep 2024

Study uncovers mechanisms behind Fuchs Endothelial Corneal Dystrophy

Important insights into the mechanisms behind Fuchs Endothelial Corneal Dystrophy (FECD), a common cause of age-related visual loss, have been revealed in a new study led by UCL researchers.

19 Sep 2024

Study reveals biomarkers that predict disability worsening in multiple sclerosis

A pioneering study presented today at ECTRIMS 2024 has identified critical biomarkers that can predict disability worsening in multiple sclerosis (MS).

19 Sep 2024

PlaqueTec and RxCelerate collaborate on early phase drug discovery for coronary artery disease

PlaqueTec, a company identifying endotype-specific biomarkers to advance precision medicine for coronary artery disease (CAD), and RxCelerate, a leading international out-sourced drug discovery and development service provider, today announced the successful completion of a collaboration to assess small molecules identified from an initial cheminformatics drug screen in a bespoke cell-based assay developed by RxCelerate on one of PlaqueTec’s targets discovered in pilot studies.

18 Sep 2024

A novel approach to biomolecule engineering

Thanks to a serendipitous discovery and a lot of painstaking work, scientists can now build biohybrid molecules that combine the homing powers of DNA with the broad functional repertoire of proteins -; without having to synthesize them one by one, researchers report in a new study. Using a naturally occurring process, laboratories can harness the existing molecule-building capacities of bacteria to generate vast libraries of potentially therapeutic DNA-protein hybrid molecules.

18 Sep 2024

Cardiovascular risks of COVID-19 antivirals

Study reviews cardiovascular side effects linked to antiviral therapies for COVID-19, highlighting the need for careful consideration when prescribing these drugs to high-risk patients.

16 Sep 2024

ISM2196: A promising AI-developed WRN inhibitor for advanced metastatic cancers

Insilico Medicine("Insilico"), a clinical-stage generative artificial intelligence (AI)-driven biotechnology company, today announced the nomination of ISM2196, an AI-driven, potential best-in-class small molecule WRN inhibitor targeting advanced metastatic microsatellite instability (MSI) cancers guided by synthetic lethality strategy.

13 Sep 2024

Current and emerging biomarkers in the management of inflammatory bowel disease

Inflammatory bowel disease (IBD), encompassing Crohn's disease (CD) and ulcerative colitis (UC), is a chronic inflammatory disorder of the gastrointestinal (GI) tract that significantly impacts the quality of life of patients.

12 Sep 2024

Ropirio Therapeutics secures exclusive license for novel lymphatic system activators

The Wyss Institute at Harvard University announced today that Ropirio Therapeutics, Inc. (Ropirio) has secured a worldwide, exclusive license from Harvard's Office of Technology Development (OTD) and Boston University (BU)'s Technology Development office for novel molecules that activate the lymphatic system - a first in the pharma industry.

11 Sep 2024

Promising new approach to combat HIV

Researchers at Université de Montréal's affiliated hospital research center, the CRCHUM, say the discovery could help lessen and even eliminate viral loads in people undergoing antiretroviral therapy.

11 Sep 2024

Once-a-day oral weight loss drug shows promising results in reducing body weight

Individuals who received a once-a-day oral weight loss drug lost up to 13% of their body weight over three months, the annual meeting of the European Association for the Study of Diabetes (EASD) in Madrid, Spain (9-13 September) will hear.

10 Sep 2024

New AI model creates virtual colorations of cancer tissue for enhanced diagnostics

A recent study published in Nature Machine Intelligence introduces an advanced artificial intelligence (AI) model capable of creating virtual colorations of cancer tissue.

10 Sep 2024

Researchers uncover connection between two common diabetes drugs with implications for foot ulcer healing

Research shows elevated metformin in diabetic foot ulcer exudates when combined with insulin, highlighting potential for improved wound healing therapies.

9 Sep 2024

Advanced imaging techniques offer insights into brain microstructure and disease detection

In a new study, researchers compared the orientations of nerve fibers in a human brainstem using two advanced imaging techniques: diffusion magnetic resonance imaging (dMRI)-based tractography and polarization sensitive optical coherence tomography (PS-OCT).

6 Sep 2024

Breakthrough technique enables clear visualization of organs in the body

Researchers have developed a new way to see organs within a body by rendering overlying tissues transparent to visible light.

6 Sep 2024

New dye technique allows for transparent skin imaging in live mice

Seeing what's going on inside a body is never easy. While technologies like CT scans, X-rays, MRIs, and microscopy can provide insights, the images are rarely completely clear and can come with side effects like radiation exposure.

5 Sep 2024

Study uncovers serotonin’s role in resilience and depression prevention

The simple act of observing others cope with a traumatic experience can increase our capacity for resilience and prevent the pathological states that can result from it, notably depression.

5 Sep 2024

Insilico Medicine partners with Inimmune to advance immunotherapeutic discovery

Insilico Medicine("Insilico"), a clinical-stage generative artificial intelligence (AI)-driven biotechnology company, today announced that the company has achieved a groundbreaking collaboration with Inimmune, which will utilize Chemistry42, Insilico's proprietary generative artificial intelligence (AI) technology to accelerate the discovery and development of next-generation immunotherapeutics.

5 Sep 2024

Molecule News and Research

Novel drug molecule offers hope for early Parkinson's disease treatment

Childhood adversity linked to elevated health risks, differing by sex and stress

Hypothalamic ECM remodeling drives insulin resistance, contributing to obesity and diabetes

Study uncovers mechanisms behind Fuchs Endothelial Corneal Dystrophy

Study reveals biomarkers that predict disability worsening in multiple sclerosis

PlaqueTec and RxCelerate collaborate on early phase drug discovery for coronary artery disease

A novel approach to biomolecule engineering

Cardiovascular risks of COVID-19 antivirals

ISM2196: A promising AI-developed WRN inhibitor for advanced metastatic cancers

Current and emerging biomarkers in the management of inflammatory bowel disease

Ropirio Therapeutics secures exclusive license for novel lymphatic system activators

Promising new approach to combat HIV

Once-a-day oral weight loss drug shows promising results in reducing body weight

New AI model creates virtual colorations of cancer tissue for enhanced diagnostics

Researchers uncover connection between two common diabetes drugs with implications for foot ulcer healing

Advanced imaging techniques offer insights into brain microstructure and disease detection

Breakthrough technique enables clear visualization of organs in the body

New dye technique allows for transparent skin imaging in live mice

Study uncovers serotonin’s role in resilience and depression prevention

Insilico Medicine partners with Inimmune to advance immunotherapeutic discovery

A new way of characterising biomolecules eBook

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

Latest News