Oxidative Stress News and Research

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Oxidative Stress is a condition in which antioxidant levels are lower than normal. Antioxidant levels are usually measured in blood plasma.

Discovery in yeast opens door to new source of information on DNA damage, repair, and cancer

The discovery in yeast cells of a genetic network that guards against lethal DNA damage is a first step in the creation of a database of disease-causing combinations of mutated human genes, according to researchers at The Johns Hopkins University School of Medicine led by Jef. D. Boeke, Ph.D.

15 Mar 2006

Smk-1 is the first known gene that regulates longevity without disrupting life-sustaining function

Within a hormone-triggered cascade of molecular signals that plays a crucial for a wide range of physiological functions, researchers for the very first time have identified a protein that functions specifically to extend lifespan and youthfulness - without disrupting fertility

13 Mar 2006

Nebivolol may restore damaged cardiovascular functions in African Americans

Tadeusz Malinski, Marvin & Ann Dilley White Professor of Chemistry and Biochemistry, found that the drug, currently under review by the U.S. Food and Drug Administration, acts on the level of oxidants lining the cardiovascular system and can restore levels of nitric oxide and reduce oxidative stress.

9 Mar 2006

Eating and drinking Cocoa helps you live longer

According to Dutch researchers, men by eating or drinking cocoa lowered their risk of dying from heart disease by 50 percent compared to those who did not eat cocoa, and also lowered their blood pressure.

28 Feb 2006

Spinocerebellar ataxia and other neurodegenerative diseases might be treatable with drugs that alter the activity of potassium channels

For the first time, researchers have linked mutations in a gene that regulates how potassium enters cells to a neurodegenerative disease and to another disorder that causes mental retardation and coordination problems.

27 Feb 2006

Removing a gene involved in repairing damaged DNA causes metabolic syndrome

Removing a gene involved in repairing damaged DNA causes mice to develop the metabolic syndrome, researchers at Oregon Health & Science University have discovered.

21 Feb 2006

Mangafodipir appears to increase the cancer-killing ability of some chemotherapy drugs

A contrast agent currently used in magnetic resonance imaging (MRI), called mangafodipir, may increase the cancer-killing ability of some chemotherapy drugs while protecting normal cells, according to a study in the Journal of the National Cancer Institute.

21 Feb 2006

Vitamin E is one of the first lines of defense in human lung tissue against the ravages of cigarette smoke

A new study has found that supplements of vitamin C can largely stop the serious depletion of vitamin E that occurs in smokers, demonstrating for the first time in humans a remarkable interaction between these two antioxidants as they work together.

17 Feb 2006

Study finds short-term lifestyle changes improve health even without major weight loss

Obese and overweight individuals suffering metabolic syndrome and Type 2 diabetes showed significant health improvements after only three weeks of diet and moderate exercise even though the participants remained overweight.

10 Jan 2006

Tomato juice keeps emphysema from developing in new animal model of degenerative disease

Feeding tomato juice to mice kept them from developing emphysema after cigarette smoke exposure that was long enough to induce emphysema in a control group, Japanese researchers report in February issue of the American Journal of Physiology-Lung Cellular and Molecular Physiology.

10 Jan 2006

Novel way to treat stroke

A joint research effort between researchers at the Burnham Institute for Medical Research in La Jolla, CA, and a team from Japan (Iwate University, Osaka City University, Gifu University, Iwate Medical University) has discovered a novel way to treat stroke and neurodegenerative disorders.

9 Jan 2006

Researchers discover how a gene linked to Parkinson’s disease can keep brain cells alive

Researchers at the University of Colorado at Denver and Health Sciences Center’s School of Medicine have uncovered how a gene linked to Parkinson’s disease can keep brain cells alive. The results suggest the possibility for new drugs that might regulate the gene and protect Parkinson’s patients from further cell damage.

29 Dec 2005

Generation of neoantigenic epitopes after posttranslational modification of Type II collagen by factors present within the inflamed joint

Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic inflammation of the joints, which gradually erodes the cartilage and bone.

7 Dec 2005

New insights into treatment of hypertension in black Americans

Researchers have reported a possible explanation for the higher risk of heart disease and its complications among black Americans, along with a way of treating this condition.

6 Dec 2005

Six gene variants predict heart muscle damage after cardiac surgery

Duke University Medical Center researchers have found that patients with six specific variants of genes involved in the body's immune response are significantly more likely to suffer damage of heart tissue after cardiac surgery.

16 Nov 2005

Lifelong exercise decreases cellular aging in the brain

In the first study to show that lifelong exercise decreases cellular aging in the brain, scientists from the McKnight Brain Institute of the University of Florida say that moderately active rats have healthier DNA and more robust brain cells than their less active counterparts. The research was presented at the Society for Neuroscience's 35th annual meeting in Washington, D.C.

13 Nov 2005

Phenolic compounds in olive oil may explain cardiovascular health benefits associated with Mediterranean Diet

Phenolic compounds in olive oil, which have antioxidant, anti-inflammatory and anti-clotting properties, may explain cardiovascular health benefits associated with the so-called Mediterranean Diet, according to a new study in the Nov. 15, 2005, issue of the Journal of the American College of Cardiology.

13 Nov 2005

Anti-aging hormone called Klotho actions explained

Scientists recently discovered an anti-aging hormone called Klotho. Now, a new study shows that this protein acts by increasing the cell's ability to detoxify harmful reactive oxygen species.

7 Nov 2005

Search for genes responsible for anxiety disorders

Increasing the activity of two enzymes better known for their role in oxidative stress metabolism turns normally relaxed mice into "Nervous Nellies," according to research conducted at the Salk Institute for Biological Studies and reported in the early online edition of Nature.

30 Oct 2005

New treatments suggest that cancer is on the run!

People suffering from cancer will be encouraged by a cluster of recent reports on successful new treatments for several different forms of cancer.

24 Oct 2005