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Research highlights the link between mitochondrial calcium transport and autophagy

An article published in The Faseb Journal describes a Brazilian study analyzing the correlation between two key energy metabolism regulation processes: the absorption and release of calcium ions by mitochondria, the organelles that generate energy for cells; and autophagy induced by calorie restriction. Autophagy occurs when cells break down and reuse their own cytoplasm.

2 May 2024

Global research offers insights about health burden disparities between genders

Globally, there are substantial differences between females and males (aged 10 and older) when it comes to health, with limited progress in bridging these health gaps over the past 30 years, according to a new study examining the disparities in the 20 leading causes of disease burden between females and males, across ages and regions, published in The Lancet Public Health journal.

2 May 2024

Study reveals global underassessment and undertreatment of chronic hepatitis B

New evidence reveals global underassessment and undertreatment of chronic hepatitis B (HBV), especially among women and Asian minorities in the West, a new study in the Journal of Hepatology, published by Elsevier, details.

2 May 2024

Study reveals molecular changes in 19 organs due to exercise

The health benefits of exercise are well known but new research shows that the body's response to exercise is more complex and far-reaching than previously thought.

2 May 2024

New drug candidate reverses obesity in mice by transforming liver metabolism

A mitochondrial transcription inhibitor (IMT) shifted metabolism in high-fat diet mice toward fatty acid oxidation, leading to weight loss, reduced liver fat, and improved glucose tolerance.

1 May 2024

Avian flu crosses species, infecting cats and cattle in Texas and Kansas

A study in the CDC's Emerging Infectious Disease Journal reports the spread of H5N1 avian influenza among cats and dairy cattle in Texas and Kansas, showing systemic illness in cattle and significant fatalities in cats exposed to the virus through infected milk.

1 May 2024

Electric pulses boost gene therapy uptake in liver cells

In an effort to improve delivery of costly medical treatments, a team of researchers in electrical engineering at the University of Wisconsin–Madison has developed a stimulating method that could make the human body more receptive to certain gene therapies.

30 Apr 2024

Genetic propensity to higher arachidonic acid levels linked to lower bipolar disorder risk

A genetic propensity to higher circulating levels of lipids containing arachidonic acid, an omega-6 polyunsaturated fatty acid found in eggs, poultry, and seafood, has been found to be linked with a lower risk for bipolar disorder, according to a new study in Biological Psychiatry, published by Elsevier.

30 Apr 2024

Specific class of drugs can reverse diet-induced obesity, fatty liver and diabetes in mice

Researchers at Karolinska Institutet may have found a new way to treat obesity and related disorders by targeting the cells' powerhouses, the mitochondria.

30 Apr 2024

Renewed classification of primary iron overload syndromes based on Hep25/FP system

The clinical introduction of hepcidin25 (Hep25) has led to a more detailed understanding of its relationship with ferroportin (FP) and divalent metal transporter1 in primary iron overload syndromes (PIOSs).

29 Apr 2024

Study reveals disparities in palliative care for people with opioid use disorder

Compared with people without opioid use disorder, those with opioid use disorder were less likely to receive palliative care in clinics and in their homes, and were dying at younger ages of causes other than opioid use, according to new research published in CMAJ (Canadian Medical Association Journal) https://www.cmaj.ca/lookup/doi/10.1503/cmaj.231419.

29 Apr 2024

New blood test shows promise in early detection of ovarian cancer

A study reveals that glycoproteins in blood could be key biomarkers for early detection and staging of epithelial ovarian cancer, potentially allowing diagnosis through a simple blood test.

28 Apr 2024

Keck Medicine of USC expands to Las Vegas for transplant care

More than 660 Nevadans need an organ transplant, according to Nevada Organ Network, a federally designated organ procurement organization; but many currently struggle to access care because of limited transplant services available in Nevada.

26 Apr 2024

Ketone supplement boosts efficacy of prostate cancer immunotherapy

Adding a pre-ketone supplement -; a component of a high-fat, low-carb ketogenic diet -; to a type of cancer therapy in a laboratory setting was highly effective for treating prostate cancer, researchers from the University of Notre Dame found.

26 Apr 2024

Single dose of malaria monoclonal antibody 77% effective in children, trial in Mali shows

One injected dose of an experimental malaria monoclonal antibody was 77% effective against malaria disease in children in Mali during the country's six-month malaria season, according to the results of a mid-stage clinical trial.

26 Apr 2024

First UK real-world study shows promise for sacituzumab govitecan in metastatic breast cancer

The real-world safety and efficacy of sacituzumab govitecan (SG) against metastatic triple-negative breast cancer.

26 Apr 2024

Exploring the potential of ketogenic diets in managing epilepsy

The mechanisms of action, efficacy, and side effects of ketogenic diet (KD) variations in epileptic patients.

26 Apr 2024

Study suggests lingering coronavirus in tissues may contribute to long COVID symptoms

Study investigated whether SARS-CoV-2 lingers in tissues after COVID-19 recovery and if it's linked to long COVID symptoms. They found viral RNA in various organs, and its presence correlated with long COVID symptoms.

25 Apr 2024

Scientists identify signaling pathway in liver cells linked to fibrosis

A healthy liver filters all the blood in your body, breaks down toxins and digests fats. It produces collagen to repair damaged cells when the liver is injured.

25 Apr 2024

MIT study reveals circadian impact on drug metabolism in engineered livers

Giving drugs at different times of day could significantly affect how they are metabolized in the liver, according to a new study from MIT.

25 Apr 2024

Liver News and Research

Research highlights the link between mitochondrial calcium transport and autophagy

Global research offers insights about health burden disparities between genders

Study reveals global underassessment and undertreatment of chronic hepatitis B

Study reveals molecular changes in 19 organs due to exercise

New drug candidate reverses obesity in mice by transforming liver metabolism

Avian flu crosses species, infecting cats and cattle in Texas and Kansas

Electric pulses boost gene therapy uptake in liver cells

Genetic propensity to higher arachidonic acid levels linked to lower bipolar disorder risk

Specific class of drugs can reverse diet-induced obesity, fatty liver and diabetes in mice

Renewed classification of primary iron overload syndromes based on Hep25/FP system

Study reveals disparities in palliative care for people with opioid use disorder

New blood test shows promise in early detection of ovarian cancer

Keck Medicine of USC expands to Las Vegas for transplant care

Ketone supplement boosts efficacy of prostate cancer immunotherapy

Single dose of malaria monoclonal antibody 77% effective in children, trial in Mali shows

First UK real-world study shows promise for sacituzumab govitecan in metastatic breast cancer

Exploring the potential of ketogenic diets in managing epilepsy

Study suggests lingering coronavirus in tissues may contribute to long COVID symptoms

Scientists identify signaling pathway in liver cells linked to fibrosis

MIT study reveals circadian impact on drug metabolism in engineered livers

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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