Pathology News and Research

RSS

Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

DoD grant awarded for investigating alternative polyadenylation in prostate cancer

A team led by Dr. Eddie Imada, assistant professor of research in pathology and laboratory medicine, has been awarded a three-year, $1.5 million United States Department of Defense grant for research on a cellular process called alternative polyadenylation and its role in prostate cancer.

10 May 2024

Understanding the metabolic changes from birth to diagnosis of autism

Researchers at the University of California San Diego School of Medicine have shed new light on the changes in metabolism that occur between birth and the presentation of autism spectrum disorder (ASD) later in childhood.

10 May 2024

Drug repurposing breakthrough: varespladib curbs snakebite-induced necrosis

Researchers discovered that venom toxins from African spitting cobras cause severe dermonecrosis, highlighting the need for targeted treatments like the repurposed drug varespladib.

9 May 2024

Deep learning models for predicting prostate cancer recurrence risk from 3D pathology datasets

Human tissue is intricate, complex and, of course, three dimensional. But the thin slices of tissue that pathologists most often use to diagnose disease are two dimensional, offering only a limited glimpse at the tissue's true complexity.

9 May 2024

New tool more accurately predicts an individual's 10-year risk of cardiovascular diseases

Collaborative research, led from the University of Oxford and published today in Nature Medicine, has developed a new tool called QR4 that more accurately predicts an individual's 10-year risk of cardiovascular diseases, like heart disease and stroke, particularly identifying high-risk patients that current prediction tools miss.

8 May 2024

Molecular pathology of Schaaf-Yang syndrome: Insights into MAGEL2 gene mutations and truncated proteins

Mutations in the MAGEL2 gene, which cause Schaaf-Yan syndrome (SYS) —an ultra-rare disease that affects neuronal and cognitive development— generate truncated, non-functional proteins that tend to accumulate in the cell nucleus.

8 May 2024

FAU researchers receive grants to tackle Alzheimer's disease

Three Florida Atlantic University researchers at the forefront of Alzheimer's disease (AD) research have each received a $350,000 grant from the Florida Department of Health's "Ed and Ethel Moore Alzheimer's Disease Research Program."

8 May 2024

APOE4 gene linked to early onset Alzheimer's, target for therapeutic intervention

A study published in Nature Medicine delineates how APOE4 homozygosity distinctly accelerates Alzheimer's disease pathology and biomarkers from the age of 55, suggesting a unique form of the disease and a potential focus for targeted therapies.

8 May 2024

Study shows cows harbor both human and avian flu receptors in their mammary glands

Study investigates the expression of influenza A virus (IAV) receptors in bovine respiratory, cerebral, and mammary tissues, revealing significant localization of human and duck receptors in mammary glands and predominant chicken receptors in the respiratory tract, which may influence the transmission and pathogenesis of IAV in cattle.

8 May 2024

Navigating the risks of patient access to immediate test results: A physician's perspective

In a fast-paced digital age where patients can open their test results as soon as they are available, what happens when a patient reads through complicated results without a physician there to help them understand what it all means? And what happens when a patient misinterprets bad news as good news, or vice versa?

7 May 2024

Unraveling the complex pathology of gastric cancer: TP53 loss and extrinsic risk factors

GC ranks as the fifth most common and fourth deadliest cancer worldwide, presenting significant health challenges, particularly in China where it is most prevalent and accounts for nearly half of newly diagnosed and death cases.

7 May 2024

Enzyme implicated in telomere repair offers new avenues for cancer therapy

A new study led by University of Pittsburgh and UPMC Hillman Cancer Center researchers shows that an enzyme called PARP1 is involved in repair of telomeres, the lengths of DNA that protect the tips of chromosomes, and that impairing this process can lead to telomere shortening and genomic instability that can cause cancer.

7 May 2024

Researchers identify novel biomarkers in renal cell carcinomas

A new study led by University of Michigan Health Rogel Cancer Center researchers identifies novel biomarkers in renal cell carcinomas.

6 May 2024

Study identifies APOE4 homozygotes as high-risk group for Alzheimer's disease

Researchers from the Research Area on Neurological Diseases, Neuroscience, and Mental Health at the Sant Pau Research Institute, led by Dr. Juan Fortea, Director of the Memory Unit of the Neurology Service at the same hospital, have found that over 95% of individuals over 65 years old who have two copies of the APOE4 gene -APOE4 homozygotes- show biological characteristics of Alzheimer's pathology in the brain or biomarkers of this disease in cerebrospinal fluid and PET scans.

6 May 2024

Evaluating ChatGPT for structured data extraction from clinical notes

Researchers evaluate the ability of ChatGPT to extract structured data from unstructured clinical notes.

5 May 2024

Eye ultrasound method may rapidly detect shunt failure in children

Use of an eye ultrasound may quickly and safely identify children with brain drainage tube failure in the emergency department, according to a new study.

3 May 2024

Machine learning tool can speed the diagnosis of undiagnosed patients with rare immune disorders

Researchers say a machine learning tool can identify many patients with rare, undiagnosed diseases years earlier, potentially improving outcomes and reducing cost and morbidity. The findings, led by researchers at UCLA Health, are described in Science Translational Medicine.

1 May 2024

Pathology News and Research

Further Reading

DoD grant awarded for investigating alternative polyadenylation in prostate cancer

Understanding the metabolic changes from birth to diagnosis of autism

Drug repurposing breakthrough: varespladib curbs snakebite-induced necrosis

Deep learning models for predicting prostate cancer recurrence risk from 3D pathology datasets

New tool more accurately predicts an individual's 10-year risk of cardiovascular diseases

Molecular pathology of Schaaf-Yang syndrome: Insights into MAGEL2 gene mutations and truncated proteins

FAU researchers receive grants to tackle Alzheimer's disease

APOE4 gene linked to early onset Alzheimer's, target for therapeutic intervention

Study shows cows harbor both human and avian flu receptors in their mammary glands

Navigating the risks of patient access to immediate test results: A physician's perspective

Unraveling the complex pathology of gastric cancer: TP53 loss and extrinsic risk factors

Enzyme implicated in telomere repair offers new avenues for cancer therapy

Researchers identify novel biomarkers in renal cell carcinomas

Study identifies APOE4 homozygotes as high-risk group for Alzheimer's disease

Evaluating ChatGPT for structured data extraction from clinical notes

Eye ultrasound method may rapidly detect shunt failure in children

Machine learning tool can speed the diagnosis of undiagnosed patients with rare immune disorders

Genetic associations of key genes in breast cancer pathogenesis

Study rethinks immune system strategies to boost vaccine effectiveness

New study reveals potential cellular mechanism behind cognitive decline in Alzheimer's

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

Latest News