Life Science White Papers

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Life Science White Papers are in-depth articles aimed to educate and inform site visitors interested in life science research. Some of these papers are derived from sources where we have existing commercial relationships. Such articles are clearly labelled as sponsored content and are only accepted when the content is deemed to add value to the core editorial ethos of News Medical.

Discover a New Approach for How to Visualize the Developing Skeleton in 3D

Discover a New Approach for How to Visualize the Developing Skeleton in 3D

This article from Thermo Fisher Scientific explores how Amira software can be used as a novel approach for visualizing the developing skeleton in 3D.

From Thermo Fisher Scientific - Software 8 Nov 2023

Studying Actin Waves Using Cryo-Electron Tomography

Studying Actin Waves Using Cryo-Electron Tomography

This article outlines how Thermo Scientific Amira software was used to study actin waves through cryo-electron tomography.

From Thermo Fisher Scientific - Software 26 Oct 2023

Monitoring Hydration State Changes of Anti-Inflammatory Agents Using Raman Spectroscopy

Monitoring Hydration State Changes of Anti-Inflammatory Agents Using Raman Spectroscopy

In drug research and development, the effect that the hydration state of active pharmaceutical ingredients (APIs) has on crystallinity is an important consideration. Variations in crystallinity influence the stability, solubility, bio-availability, and dissolution rate of the drug. Therefore, knowing the effect that humidity has on the stability of different states is important, from both a regulatory and safety standpoint.

From Surface Measurement Systems Ltd 12 Oct 2023

Dynamic Vapor Sorption for the Determination of Moisture-Induced Glass Transition in an Amorphous Pharmaceutical

Dynamic Vapor Sorption for the Determination of Moisture-Induced Glass Transition in an Amorphous Pharmaceutical

A new method to determine the onset relative humidity for a glass transition in an amorphous material was developed using the DVS. Water vapour can act as a plasticising agent in amorphous materials, causing a recrystallisation event below the glass transition temperature. This method calculates the threshold relative humidity for this moisture induced glass transition at a particular temperature.

From Surface Measurement Systems Ltd 12 Oct 2023

Use of Optical Microscopy for the Investigation of Dried Milk Powders under Varying Humidity Conditions

Use of Optical Microscopy for the Investigation of Dried Milk Powders under Varying Humidity Conditions

The effects of humidity are evident in the stability and shelf-life of a variety of materials, formulations, and processing behaviour, especially food materials. This article discusses the advantages of a direct comparison method of three similar dried milk samples under varying humidity conditions, using optical microscopy in conjunction with the GenRH-A accessory and Mcell from Surface Measurement Systems.

From Surface Measurement Systems Ltd 12 Oct 2023

Using Inverse Gas Chromatography (iGC SEA) to Identify Variations in the Dissolution Rate of Pharmaceutical Drugs

Using Inverse Gas Chromatography (iGC SEA) to Identify Variations in the Dissolution Rate of Pharmaceutical Drugs

Active materials with batch-to-batch variations present a major issue to the pharmaceutical industry. On the whole, any batch-to-batch variation is undesirable. The range of techniques available for the characterization, analysis, and discrimination of products that are chemically identical can be restricted by the nature of the materials, and the sensitivity to slight physicochemical variations between them.

From Surface Measurement Systems Ltd 12 Oct 2023

Using Vapor Sorption Techniques to Identify and Characterize Pharmaceutical Materials

Using Vapor Sorption Techniques to Identify and Characterize Pharmaceutical Materials

Most pharmaceutical materials can exist in a desired crystalline state with an ordered lattice structure. There are several different crystalline forms of the same material available, such as polymorphs and/or solvated crystal forms.

From Surface Measurement Systems Ltd 12 Oct 2023

Using static SIMS to identify molecular signals

Using static SIMS to identify molecular signals

Static SIMS can be used to confirm the presence of a drug, between other applications, by identifying molecular signals such as binding or dehydrating.

From Hiden Analytical 15 Sep 2023

What is plasma medicine?

What is plasma medicine?

In this article, Hiden Analytical gives a detailed overview of plasma medicine - from the available technology to the areas of application.

From Hiden Analytical 15 Sep 2023

Multiomics: An overview of useful methods and applications

Multiomics: An overview of useful methods and applications

Learn about how to get more information from your samples using multiomics workflows in the updated Multiomics Methods Guide, now featuring Illumina’s most innovative platforms, NovaSeq™ X and X Plus Sequencing Systems.

From Illumina, Inc. 7 Sep 2023

Expert panel discussion – accelerating precision medicine with low-cost whole-genome sequencing

Expert panel discussion – accelerating precision medicine with low-cost whole-genome sequencing

Next-generation sequencing (NGS) will have a dramatic impact on healthcare in the next decade. But what are the real benefits of this trend? Learn more in this expert panel on accelerating precision medicine with low-cost whole-genome sequencing.

From Illumina, Inc. 7 Sep 2023

What is metatranscriptomics?

What is metatranscriptomics?

Metatranscriptomics takes on the daunting task of unraveling the delicate balance between humans and the trillions of microbial cells in residence. To comprehensively profile the microbiome, researchers are deploying multiomics to understand the microbiome’s role in human health.

From Illumina, Inc. 7 Sep 2023

Empower transcriptomics with RNA sequencing

Empower transcriptomics with RNA sequencing

Download this Gene Expression and Regulation eBook to explore how next-generation sequencing (NGS) is accelerating high impact studies using bulk or single-cell RNA-Seq applications.

From Illumina, Inc. 7 Sep 2023

Discover single-cell sequencing workflows

Discover single-cell sequencing workflows

Learn valuable insights for experimental success for single-cell sequencing. Discover how using single cell analysis can reveal cell types, functions and interactions within a complex biological microenvironment.

From Illumina, Inc. 7 Sep 2023

Proteomics and transcriptomics with universal NGS readout

Proteomics and transcriptomics with universal NGS readout

In this guide, learn how proteomics via next-generation sequencing (NGS) can be used to study biological processes, tumor biology, biomarker discovery and host-pathogen interactions, expanding a new era in proteogenomics.

From Illumina, Inc. 7 Sep 2023

Infographic - publication highlights for spatial analysis

Infographic - publication highlights for spatial analysis

NGS-based spatial analysis allows researchers to capture transcriptomic and proteomic information from cells within their native tissue environment, offering a multidimensional approach to understand gene expression and regulatory pathway mechanisms.

From Illumina, Inc. 7 Sep 2023

Cost-effective and high-throughput NGS boosts prospects for widespread personalized medicine

Cost-effective and high-throughput NGS boosts prospects for widespread personalized medicine

Learn more about the Illumina IVD-compliant high throughput sequencing instrument. The NovaSeq™ 6000Dx offers operational simplicity and the flexibility of NGS in either IVD or research use only (RUO) mode.

From Illumina, Inc. 7 Sep 2023

Ask the experts: Tips and best practices for DNA methylation studies

Ask the experts: Tips and best practices for DNA methylation studies

Article featuring interviews with leading experts who discuss the impact of DNA methylation in biological processes involved in development and aging, and disease states like cancer and neurological disorders.

From Illumina, Inc. 7 Sep 2023

Temperature Control and Heat Exchange in Bioreactors

Temperature Control and Heat Exchange in Bioreactors

High-quality temperature controllers are essential for bioreactors and describes some of the recent applications of PolyScience temperature control solutions.

From PolyScience 31 Aug 2023

Recirculating Chillers for GC-MS Systems

Recirculating Chillers for GC-MS Systems

Importance of temperature control during Mass Spectrometry experiments and how Polyscience solutions can help provide optimal conditions.

From PolyScience 31 Aug 2023

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