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New compound extracted from African catfish skin mucas exhibits powerful antibacterial properties

Scientists report they have extracted a compound with powerful antibacterial properties from the skin of farmed African catfish.

25 Mar 2024

Generative artificial intelligence model can easily design billions of novel antibiotics

Researchers at McMaster University and Stanford University have invented a new generative artificial intelligence model which can design billions of new antibiotic molecules that are inexpensive and easy to build in the laboratory.

22 Mar 2024

New "fusion sites" enable faster and more targeted drug development

Many important medicines, such as antibiotics and anticancer drugs, are derived from natural products from Bacteria.

22 Mar 2024

Researchers devise novel technique for crafting human artificial chromosomes

Human artificial chromosomes (HACs) capable of working within human cells could power advanced gene therapies, including those addressing some cancers, along with many laboratory applications, though serious technical obstacles have hindered their development.

21 Mar 2024

Study illuminates untapped potential of the shrub sea buckthorn as a source of natural antioxidants

New research, published in SCI's Journal of the Science of Food and Agriculture illuminates the untapped potential of the shrub sea buckthorn as a rich source of natural antioxidants in North America.

21 Mar 2024

Researchers identify mechanism behind COVID-19 related brain fog

Among the many confounding symptoms in patients recovering from a COVID-19 infection are memory loss and difficulty learning.

21 Mar 2024

Study challenges previously held views on brain preservation in archaeology

Soft tissue preservation in the geological record is relatively rare, and, except where deliberate intervention halts the process of decay (like embalming or freezing), the survival of entire organs is particularly unusual.

21 Mar 2024

Study reveals cellular dynamics of multiple sclerosis lesions

Using advanced methodology, scientists in Sweden were able to reveal at the cellular level how lesions in multiple sclerosis develop.

20 Mar 2024

Researchers create a method to determine psilocybin and psilocin potency in mushrooms

Since the 1970s, the federal government has listed the active ingredients in mushrooms-;psilocybin and psilocin-;as illegal and having no accepted medical use.

18 Mar 2024

Newly discovered adhesion GPCR mayo controls midgut development in Drosophila

Adhesion GPCRs belong to the large family of G protein-coupled receptors (GPCRs). There are about 700 variants in humans, which are responsible for sensory impressions, hormonal cycles, controlling the cardiovascular system and more.

15 Mar 2024

Study uncovers mutation impacting Alzheimer's progression

The scientist of the Faculty of Medicine of the University of Malaga José Luis Royo has coordinated a study that summarizes eight years of research and brings together 100 multidisciplinary specialists, identifying a mutation that alters Alzheimer's disease progression.

15 Mar 2024

New drug candidate designed at the atomic level could help halt emerging SARS-CoV-2 variants

Although COVID-19 has faded from the headlines, SARS-CoV-2 – the coronavirus behind the pandemic – is still rampantly infecting people around the world.

14 Mar 2024

Neurobiologists unravel how stress triggers generalized fear

Our nervous systems are naturally wired to sense fear. Whether prompted by the eerie noises we hear alone in the dark or the approaching growl of a threatening animal, our fear response is a survival mechanism that tells us to remain alert and avoid dangerous situations.

14 Mar 2024

New custom-designed proteins can efficiently reach intramembrane targets

Hitting targets embedded within the cell membrane has long been difficult for drug developers due to the membrane's challenging biochemical properties. Now, Scripps Research chemists have demonstrated new custom-designed proteins that can efficiently reach these "intramembrane" targets.

13 Mar 2024

Increased stiffness in aging skin may contribute to higher rates of metastatic skin cancer

Age-related changes that cause the skin to stiffen and become less elastic may also contribute to higher rates of metastatic skin cancer in older people, according to research by investigators from the Johns Hopkins Kimmel Cancer Center.

12 Mar 2024

UCLA and UAMS teams secure $3.2 million NIH grant for melanoma research

A team of investigators from the UCLA Health Jonsson Comprehensive Cancer and the University of Arkansas for Medical Sciences (UAMS) Winthrop P. Rockefeller Cancer Institute was awarded a $3.2 million grant from the National Institutes of Health to identify new ways to prevent and overcome treatment resistance to targeted therapy in patients with all sub-types of cutaneous melanoma, an aggressive form of skin cancer.

11 Mar 2024