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Researchers uncover two classes of genetic causes for pediatric chordoma

Little is known about the genetics and biology of chordoma, a rare and aggressive bone tumor. Chordomas occur in approximately one in a million people in the U.S. a year and only five percent of these are in children.

30 May 2024

Study may facilitate the development of new personalized treatments for schizophrenia An International Study Publi...

An international study led by the Hospital del Mar Medical Research Institute, in collaboration with researchers from the Neuropsychopharmacology Group at the University of the Basque Country (UPV/EHU) and researchers from the CIBER of Mental Health (CIBERSAM), and published in Nature Communications, may facilitate the creation of new personalized treatments for people diagnosed with schizophrenia.

30 May 2024

Genomic evidence of prenatal origins in childhood acute myeloid leukemia

A team of researchers from the Institute of Oncology of the University of Oviedo (IUOPA), the Josep Carreras leukemia Research Institute, the University of Barcelona and the Centre for Biomedical Research in Cancer Network (CIBERONC) have demonstrated that some childhood leukemia originate during embryonic development, although they do not manifest after a few months after birth.

30 May 2024

How tight binding between immune cells dictates T cell cancer-fighting ability

Immunotherapy, treatments that reinvigorate immune cells' anti-cancer activity or reprogram T cells to target cancer, has shown promise in treating leukemias but has not yet been realized in solid tumors.

30 May 2024

A nutrition screener developed for improving access to federal food benefits

Researchers from The Possibilities Project and Clinical Futures at Children's Hospital of Philadelphia (CHOP) developed, implemented and successfully tested a nutrition screener to improve access to healthy resources for families eligible for federally funded food benefits.

30 May 2024

Mast cells and PGE2: Key players in controlling asthma inflammation

Previous research indicates that mast cells, a type of immune cell found in the tissues throughout the body, cause inflammation during an asthma attack, inducing symptoms such as trouble breathing and narrowing of the airways.

30 May 2024

Memory decline reported by patients and partners may signal early Alzheimer's changes

A new study adds further evidence that when a patient or family member notices signs of persistent memory loss, it's important to speak with a doctor.

30 May 2024

Statins may block an inflammation pathway involved in the development of cancer

A new study led by investigators from Mass General Cancer Center, a founding member of the Mass General Brigham healthcare system, reveals that statins-;commonly used cholesterol-lowering drugs-;may block a particular pathway involved in the development of cancer that results from chronic inflammation.

30 May 2024

RCSI and Head Diagnostics collaborate to revolutionize multiple sclerosis assessment

RCSI has partnered with Head Diagnostics (Dublin, Ireland) on a clinical study to enhance the assessment and monitoring of Multiple Sclerosis (MS) through innovative technology.

30 May 2024

Safety-net health clinics cut services and staff amid Medicaid ‘unwinding’

One of Montana's largest health clinics that serves people in poverty has cut back services and laid off workers.

30 May 2024

An obscure drug discount program stifles use of federal lifeline by rural hospitals

Facing ongoing concerns about rural hospital closures, Capitol Hill lawmakers have introduced a spate of proposals to fix a federal program created to keep lifesaving services in small towns nationwide.

30 May 2024

Transparent skull implant unveils new frontiers in brain imaging

In the first study of its kind, researchers from the Keck School of Medicine of USC and the California Institute of Technology (Caltech) designed and implanted a transparent window in the skull of a patient, then used functional ultrasound imaging (fUSI) to collect high-resolution brain imaging data through the window.

29 May 2024

New antibiotic lolamicin shows promise in fighting drug-resistant infections

Researchers have developed a new antibiotic that reduced or eliminated drug-resistant bacterial infections in mouse models of acute pneumonia and sepsis while sparing healthy microbes in the mouse gut.

29 May 2024

Timely transition from pediatric to adult care reduces hospitalizations for sickle cell patients

Individuals living with sickle cell disease (SCD) who experience a delay of more than six months in transitioning from pediatric to adult care are twice as likely to be hospitalized compared to those who transition in less than two months, according to a study published in Blood Advances.

29 May 2024

RNA-based therapy shows promise in reducing cholesterol and triglycerides

A small interfering RNA (siRNA) investigational therapy that inhibits a gene involved in lipoprotein metabolism has been shown in a clinical trial led by Mount Sinai researchers to significantly reduce levels of different types of cholesterol and triglycerides in individuals with mixed hyperlipidemia, a condition in which fats build up in the blood.

29 May 2024

Study finds kidney complications following heart failure hospitalization

In a study of Medicare beneficiaries, researchers from Brigham and Women's Hospital found that one year after hospitalization for heart failure, 6 percent of patients had progressed to dialysis.

29 May 2024

Novel method creates antibody-peptide inhibitor conjugates with enhanced therapeutic efficacy

Tumor cells often hijack normal physiological processes to support their growth, exploiting proteins that are in charge of essential cell functions.

29 May 2024

Tennessee gives this hospital monopoly an A grade — even when it reports failure

A Tennessee agency that is supposed to hold accountable and grade the nation's largest state-sanctioned hospital monopoly awards full credit on dozens of quality-of-care measurements as long as it reports any value — regardless of how its hospitals actually perform.

29 May 2024

Evaluating the efficacy of harmol in treating herpes simplex virus-induced keratitis

The antiviral efficacy and therapeutic potential of harmol in treating herpes simplex virus type 1 (HSV-1) induced keratitis

29 May 2024

Decline in family physicians’ outpatient Medicare procedures amid aging demographic trends

Family physicians perform a wide range of procedures outside the hospital and tend to be office based. Examples may include surgical procedures such as excisions, suturing, and joint injections.

28 May 2024

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Hospital News and Research

Researchers uncover two classes of genetic causes for pediatric chordoma

Study may facilitate the development of new personalized treatments for schizophrenia An International Study Publi...

Genomic evidence of prenatal origins in childhood acute myeloid leukemia

How tight binding between immune cells dictates T cell cancer-fighting ability

A nutrition screener developed for improving access to federal food benefits

Mast cells and PGE2: Key players in controlling asthma inflammation

Memory decline reported by patients and partners may signal early Alzheimer's changes

Statins may block an inflammation pathway involved in the development of cancer

RCSI and Head Diagnostics collaborate to revolutionize multiple sclerosis assessment

Safety-net health clinics cut services and staff amid Medicaid ‘unwinding’

An obscure drug discount program stifles use of federal lifeline by rural hospitals

Transparent skull implant unveils new frontiers in brain imaging

New antibiotic lolamicin shows promise in fighting drug-resistant infections

Timely transition from pediatric to adult care reduces hospitalizations for sickle cell patients

RNA-based therapy shows promise in reducing cholesterol and triglycerides

Study finds kidney complications following heart failure hospitalization

Novel method creates antibody-peptide inhibitor conjugates with enhanced therapeutic efficacy

Tennessee gives this hospital monopoly an A grade — even when it reports failure

Evaluating the efficacy of harmol in treating herpes simplex virus-induced keratitis

Decline in family physicians’ outpatient Medicare procedures amid aging demographic trends

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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