Biochemistry

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Chocolate's delicious chemistry may hide risks in baked sweet treats

What makes chocolate taste and smell so delicious? Chemistry, of course! A variety of molecules work together to create that unmistakable aroma, but those same molecules might carry some unwanted health effects if there are too many around.

29 May 2024

Proline-based nano cages offer targeted drug delivery, limit side effects of chemotherapy

A new method of drug delivery using proline, an amino acid found in chicken feathers and skin tissue, could be used to limit the side effects of chemotherapy and repair important enzymes, new research suggests.

29 May 2024

Scientists design new way to "cloak" proteins for targeted therapeutic delivery

Cornell University scientists have designed a way to "cloak" proteins in a generalized technique that could lead to repurposing things like antibodies for biological research and therapeutic applications.

28 May 2024

Two analytical methods developed to analyze several antibiotics in vegetables and earthworms

UPV/EHU researcher Irantzu Vergara has managed to analyze, simultaneously, several families of antibiotics in vegetables and earthworms.

24 May 2024

Mammal-specific domain of the prion protein may hold clues to neurodegenerative diseases

A study from Bochum describes a mammal-specific domain of the prion protein and offers new approaches for research into neurodegenerative diseases.

23 May 2024

New MOBE technology revolutionizes multiplexed genome editing

The human genome consists of around 3 billion base pairs and humans are all 99.6% identical in their genetic makeup.

21 May 2024

Researchers trace the evolution of key plant protein in lignin synthesis

Scientists from the U.S. Department of Energy's (DOE) Brookhaven National Laboratory have discovered that a protein responsible for the synthesis of a key plant material evolved much earlier than suspected.

17 May 2024

Reviving a rejected drug: New selective antibiotic shows promise

Twenty years ago, a drug candidate was rejected due to its side effects. Researchers have now figured out how to potentially make a successor molecule more selective.

17 May 2024

Lactate is essential to buffering the effects of a carbohydrate meal, study shows

As a student competing in track and field at his Parlier high school, Robert Leija was obsessed with how to improve his performance and, in particular, prevent the buildup of lactic acid in his muscles during training.

15 May 2024

St. Jude researchers unveil mechanisms to block PXR and enhance drug potency

Deaths from cancer or infections can occur when available treatments are ineffective. Once turned on, pregnane X receptor (PXR) activates the expression of genes encoding enzymes that metabolize external chemicals, including drugs.

14 May 2024

New mechanism discovered to weaken pseudomonas aeruginosa virulence

The opportunistic bacterial pathogen Pseudomonas aeruginosa is dangerous due to its resistance to multiple antibiotics.

14 May 2024

Research explores the effects of nuclear magnetic resonance on internal clock of cells

A research collaboration between the Faculty of Biochemistry and Molecular Medicine at the University of Oulu, Finland, the University of Innsbruck, Austria, and Florida Tech, USA, explored the effects of nuclear magnetic resonance on the internal clock of cells at different times of day and under oxygen deprivation.

13 May 2024

UC San Diego's open source AI platform revolutionizes multi-target drug discovery

Scientists at UC San Diego have developed a machine learning algorithm to simulate the time-consuming chemistry involved in the earliest phases of drug discovery, which could significantly streamline the process and open doors for never-before-seen treatments.

6 May 2024

Study reveals impact of Mediator protein complex on cell division regulation

Researchers at Umeå University, Sweden, have discovered that how a special protein complex called the Mediator moves along genes in DNA may have an impact on how cells divide.

3 May 2024

Specific class of drugs can reverse diet-induced obesity, fatty liver and diabetes in mice

Researchers at Karolinska Institutet may have found a new way to treat obesity and related disorders by targeting the cells' powerhouses, the mitochondria.

30 Apr 2024

Formulation and stability evaluation of honey-loaded nanoemulsion for topical delivery

Honey is a viscous, hygroscopic liquid in nature. It has the ability to treat wounds, wrinkles, aging, and inflammation. This study's objective was to create and characterize a nanoemulsion containing honey and evaluate its stability.

29 Apr 2024

Sino Biological finalizes the acquisition of SignalChem Biotech, strengthening global presence and expanding product portfolio

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From Sino Biological Inc. 29 Apr 2024