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Scientists identify immune-system mutation

A team of Fox Chase Cancer Center scientists led by immunologist Dietmar J. Kappes, Ph.D., has identified the genetic mutation that keeps a mouse strain from developing white blood cells, or lymphocytes, called helper T cells. The report by Kappes and his colleagues appears in the Feb. 24 issue of Nature.

27 Feb 2005

Beginning of new wave - first generation to turn 18 since technology and treatments have allowed them to survive to adulthood

More than half a million children with special health-care needs will turn 18 this year, the first generation to reach adulthood since sweeping medical advances ensured an unprecedented number would survive congenital conditions that until recently would have killed them.

27 Feb 2005

Early Alzheimer's disease may be precipitated by a neuron traffic jam

Early Alzheimer's disease may be precipitated by a “traffic jam” within neurons that causes swelling and prevents proper transport of proteins and structures in the cells, according to new studies by Howard Hughes Medical Institute researchers.

27 Feb 2005

Shigella infects cells by using a secretion system to inject proteins into human cells

According to research published in Science, the team from Imperial College London and Institut Pasteur, Paris, found that shigella, the bacteria which causes dysentery, is able to invade cells, while stopping any response from the immune system.

27 Feb 2005

Is caesarean section linked to postnatal depression?

According to a recent study elective Caesarean section does not protect women from postnatal depression. Emergency caesarean section or assisted vaginal delivery (use of forceps or vacuum extraction) do not indicate a possible increased risk of postnatal depression.

27 Feb 2005

Americans believe drug industry cares more about profits than people

Americans believe prescription drugs are improving their lives, but most also say that the drug industry cares more about profits than people, according to the latest Kaiser Health Poll Report issued by the Kaiser Family Foundation.

27 Feb 2005

Differences in how HIV virus infects males and females

A genetic analysis of viral RNA from 10 heterosexual couples, in which one partner has sexually transmitted HIV to the other, provides the first documentation of some differences in how the virus infects males and females.

27 Feb 2005

Second-generation Antidepressants

A recent article in the prestigious British Medical Journal seems to confirm an increased risk for suicidal behavior among adults taking popular antidepressants. This follows evidence that certain selective serotonin reuptake inhibitors (SSRIs) may have a similar effect among children and adolescents.

27 Feb 2005

Tobacco industry influences research

At a tobacco industry meeting in 1987 to consider how to ‘improve the industry’s position’on passive smoking, one of the strategies proposed by Philip Morris USA was to ‘establish a genuine scientific journal on indoor air quality’. In 1989 the International Society of the Built Environment, was established.

27 Feb 2005

NIH awards grant to explore causal relationship between epoetin dose and survival of hemodialysis patients

The National Institutes of Health, National Institute of Diabetes & Digestive & Kidney Diseases (NIDDK) has awarded a two-year grant to the Medical Technology and Practice Patterns Institute (MTPPI) in collaboration with Harvard School of Public Health (HSPH) to explore the causal relationship between epoetin dose and survival of hemodialysis patients receiving this therapy.

27 Feb 2005

Common epigenetic problem doubles cancer risk

In experiments with mice, a team of scientists from the United States, Sweden and Japan has discovered that having a double dose of one protein is sufficient to change the normal balance of cells within the lining of the colon, thereby doubling the risk that a cancer-causing genetic mutation will trigger a tumor there.

27 Feb 2005

Genzyme begins gene transfer trial for peripheral arterial disease

Genzyme Corporation announced today that the first patient has been treated in a new phase 2 clinical trial examining the safety and effectiveness of locally delivered gene transfer for patients with peripheral arterial disease.

24 Feb 2005

Childhood obesity is a serious health problem in Australia

Professor Michael Booth, co-director of the University of Sydney's Centre for Overweight and Obesity, said teenagers were already showing signs of serious illness caused by their weight.

24 Feb 2005

Pfizer acquires Idun Pharmaceuticals

Pfizer today announced that it has entered into an agreement to acquire Idun Pharmaceuticals, a biopharmaceutical company focused on the discovery and development of therapies to control apoptosis, a process of cell death that occurs in a broad range of diseases.

24 Feb 2005

$71 million to launch a new drug

Mid-level pharmaceutical brands invest an average of $71 million in marketing between Phase III trials and the first year on the market, according to a new report from Cutting Edge Information.

24 Feb 2005

Should screening for sleep apnea be required for all men?

According to a new study, men in their 20s need to be screened the most. That's because men aged 20 to 29 with severe sleep apnea have 10 times the risk of dying from heart related ailments than their non sleep apnea peers in the general population, and a much higher risk than older men with sleep apnea.

24 Feb 2005

Sexual banter in the workplace is OK, sex might be an issue though!

Sexualized encounters in some work situations actually can contribute to building camaraderie in a workforce, according to a new study by a University of Washington, Bothell, sociologist who examines sexual banter and power in the workplace.

24 Feb 2005

Counseling smokers to quit reduced their chances of dying

Giving up smoking after a heart attack has been clearly associated with improvements in long-term patient survival, but how soon after myocardial infarction does smoking cessation begin to have positive effects?

24 Feb 2005

New imaging method that may provide a clearer diagnosis of breast cancer

"This technique involves a new method for interpreting information gathered through MRI," explained Springer. "The technique involves recognizing that certain properties of MRI signals can change during the examination, much like the changing of a camera's shutter speed.

24 Feb 2005

$Osteochondral allograft and microfracture procedures restore patient mobility$

Osteochondral allograft and microfracture procedures restore patient mobility

Two separate new studies presented at a major medical meeting provide objective scientific evidence that the two most commonly performed cartilage repair techniques are effective at restoring patient mobility and reducing pain.

24 Feb 2005