Signaling Pathway News and Research

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Curcumin can suppress metastasis of colorectal cancer cells by activating a specific signaling pathway

LMU researchers have identified a signaling pathway via which curcumin can suppress the metastasis of colorectal cancer cells.

25 May 2023

Newly identified genetic variant provides protection from Alzheimer's disease

A single patient can spark new research questions and provide answers about a disease. And when a new case is identified, investigators can make connections between them that can lead to even more powerful and persuasive ideas about cause and treatment.

15 May 2023

Study offers hope for better recovery of stroke patients

Ischemic stroke, caused by a blockage of blood flow to the brain, is a common cause of death and disability.

11 May 2023

Researchers develop gene-edited stem cells to reduce arrhythmias in heart attack patients

In a recent study published in the journal Cell Stem Cell, researchers hypothesized that pacemaker-like activity of human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) resulted in engraftment arrhythmias (EAs), which hampers the clinical use of cell-based therapy using hPSC-CMs for treatment of myocardial infarction (MI).

2 May 2023

The role of diet in managing type 2 diabetes: insights into individualized medical nutritional therapy

Researchers investigated the use of medical nutrition therapy for type 2 diabetes mellitus patients.

2 May 2023

Researchers identify a druggable copper-signaling pathway that drives inflammation

Inflammation is a complex biological process that can eradicate pathogens and promotes repair of damaged tissues.

27 Apr 2023

Study sheds light on immune factors responsible for contrasting SARS-CoV-2 outcomes in humans and white-tailed deer

Researchers explored the response of respiratory epithelial cells in deers to SARS-CoV-2.

27 Apr 2023

Novel cell signaling pathway could be targeted against aggressive pancreatic cancers

Researchers at the Johns Hopkins Kimmel Cancer Center identified a novel cell signaling pathway that potentially could be targeted in therapy for patients with aggressive pancreatic cancers.

24 Apr 2023

Exploring the tantalizing questions about sleep

Sleep is one of the most essential human activities -; so essential, in fact, that if we don't get enough sleep for even one night, we may struggle to think, react, and otherwise make it through the day.

11 Apr 2023

Dietary supplement N-acetylcysteine helps overcome treatment resistance in breast cancer

Many cancer therapies do not produce the hoped-for results. A common reason for this is that the tumors develop resistance to the medication.

11 Apr 2023

Is mRNA decoding in humans structurally and kinetically distinct from bacteria?

Researchers examined molecular-level differences in ribosomal translational fidelity between humans and bacteria.

7 Apr 2023

Study suggests new strategy to ward off age-related weight gain

New research suggests a strategy to ward off age-related weight gain, which could prevent obesity and associated health disorders like Type 2 diabetes, heart disease and chronic inflammation.

7 Apr 2023

Researchers develop a biosensor for real time detection of the G-protein molecular switch

DGIST (President: Kook Yang) announced on March 16th that the research team led by Professor Byung-Chang Suh has investigated for the first time the real-time effect of the G-protein cycle, which acts as a switch in our body, on the structural changes in G protein-coupled receptors (GPCRs).

31 Mar 2023

Black sea urchin extract shows promise in combating atherosclerosis

A team of Italian scientists has identified potential anti-inflammatory and vasculoprotective effects of red cell extracts of the Black Sea urchin Arbacia lixula. The study has been published in the journal Nutrients.

30 Mar 2023

Experimental anti-obesity drug may control appetite without surgery or nausea

Imagine getting the benefits of gastric bypass surgery without going under the knife -; a new class of compounds could do just that. In lab animals, these potential treatments reduce weight dramatically and lower blood glucose.

29 Mar 2023

Drugs to activate STING could help prevent cancer metastasis

A team of scientists at the Sloan Kettering Institute have identified the STING cellular signaling pathway as a key player in keeping dormant cancer cells from progressing into aggressive tumors months, or even years, after they've escaped from a primary tumor.

29 Mar 2023

Signaling Pathway News and Research

Curcumin can suppress metastasis of colorectal cancer cells by activating a specific signaling pathway

Newly identified genetic variant provides protection from Alzheimer's disease

Study offers hope for better recovery of stroke patients

Researchers develop gene-edited stem cells to reduce arrhythmias in heart attack patients

The role of diet in managing type 2 diabetes: insights into individualized medical nutritional therapy

Researchers identify a druggable copper-signaling pathway that drives inflammation

Study sheds light on immune factors responsible for contrasting SARS-CoV-2 outcomes in humans and white-tailed deer

Novel cell signaling pathway could be targeted against aggressive pancreatic cancers

Exploring the tantalizing questions about sleep

Dietary supplement N-acetylcysteine helps overcome treatment resistance in breast cancer

Is mRNA decoding in humans structurally and kinetically distinct from bacteria?

Study suggests new strategy to ward off age-related weight gain

Researchers develop a biosensor for real time detection of the G-protein molecular switch

Black sea urchin extract shows promise in combating atherosclerosis

Experimental anti-obesity drug may control appetite without surgery or nausea

Drugs to activate STING could help prevent cancer metastasis

Targeting obesity: findings reveal a new molecular pathway involved in energy homeostasis regulation

Newly found strategy used by metastasized tumors may explain why some promising immunotherapies fail

Targeting the STING pathway with a combination strategy promotes antitumor activity

How does diet affect inflammation?

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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