Genetic News and Research

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Researchers discover novel way to increase amounts of antibiotics

A novel way of increasing the amounts of antibiotics produced by bacteria has been discovered that could markedly improve the yields of these important compounds in commercial production. It could also be valuable in helping to discover new compounds. With the ever-growing threat from antibiotic resistance, these tools will be very useful in ensuring that we have enough of these useful compounds in the future.

5 Sep 2011

Cancer cells with specific genetic defect extra susceptible to therapy that damages DNA

Using a strategy based on treating cancer cells that carry a specific genetic signature - hyper-expression of the protein Myc - with therapy that affects the stability of the cell's DNA, more effective results can be achieved.

5 Sep 2011

Autism diagnosis by brain scan a possibility

A team of Stanford scientists have found that the brains of autistic children have a distinctive topography and could be captured using new imaging techniques. This could someday create a template for the autistic brain that could be used to diagnose kids at a very early age they claim.

5 Sep 2011

Researchers discover gene mutation linked with lymphoedema, leukaemia

Researchers have discovered a gene that when mutated can cause lymphoedema (swollen limbs due to a failure of the lymph system), immune abnormalities, deafness and leukaemia.

5 Sep 2011

Researchers discover group of mutations involved in T-cell acute lymphoblastic leukemia

An international team of researchers has found a group of mutations involved in T-cell acute lymphoblastic leukemia (T-ALL), and showed that a group of certain drugs, already in clinical use to treat other diseases, can eliminate the cells carrying these mutations.

5 Sep 2011

Researchers discover new genetic defect that predisposes people to leukemia, myelodysplasia

A new genetic defect that predisposes people to acute myeloid leukemia and myelodysplasia has been discovered. The mutations were found in the GATA2 gene. Among its several regulatory roles, the gene acts as a master control during the transition of primitive blood-forming cells into white blood cells.

5 Sep 2011

Scientists sequence ten variants of E. coli O104:H4 outbreak strain across the world

Ten variants of the deadly Escherichia coli strain that hit Germany in May 2011 have been sequenced across the world. The unprecedented level of collaboration across the scientific community should give insight into how the outbreak arose, says a scientist at the Society for General Microbiology's Autumn Conference 2011.

5 Sep 2011

Resveratrol helps prevent metabolic syndrome in offspring

Researchers in the Faculty of Medicine & Dentistry at the University of Alberta have discovered that resveratrol, a powerful antioxidant found in common foods, prevents a syndrome in some offspring that could lead to later health issues such as diabetes.

3 Sep 2011

Scientists identify several links between genetic variants and specific metabolic changes

Scientists at Helmholtz Zentrum Munich and LMU Munich, in cooperation with Wellcome Trust Sanger Institute and King's College London (KCL), have identified several associations between genetic variants and specific metabolic changes.

3 Sep 2011

Nature journal publishes Metabolon's genome wide association study

Metabolon, Inc., the leader in metabolomics, biomarker discovery and biochemical analysis, announced the publication of "Human Metabolic Individuality in Biomedical and Pharmaceutical Research" in the journal Nature.

3 Sep 2011

Finland national health institute finds link between H1N1 flu vaccine and children's narcolepsy

"Finland's national health institute said on Thursday its latest research on previously found links between children's narcolepsy and GlaxoSmithKline's Pandemrix vaccine against H1N1 swine flu also involved a genetic risk factor," Reuters reports.

3 Sep 2011

Scientists uncover one of the benefits of non-monogamous relationships

It's all about the grandkids! That's what a team led by an Indiana University biologist has learned about promiscuous female birds and why they mate outside their social pair.

3 Sep 2011

Plerixafor drug shows promise against WHIM syndrome

A new study reports that a drug already approved by the Food and Drug Administration for use in patients undergoing a bone marrow transplant may also have promise for treating people who have a rare immune deficiency known as WHIM syndrome.

3 Sep 2011

SWOG selects four cancer researchers for 2011 Young Investigator Training Course

SWOG has selected four talented, early-career researchers for its 2011 Young Investigator Training Course. These four will attend a three-day workshop September 19 - 21 in Seattle, Wash., for intensive training in how to design and conduct cancer clinical trials.

3 Sep 2011

More strides against childhood cancer

The treatment of childhood cancer is one of the great success stories of modern medicine. A few decades ago, only 20 percent of children survived the disease. Today, overall survival rates approach 80 percent. Yet cancer remains the leading cause of death from disease in U.S. children older than 1 year of age, and some types of pediatric cancer continue to have poor survival rates.

2 Sep 2011

PTC restructures collaboration with Genzyme

PTC Therapeutics, Inc. and Genzyme, a Sanofi company, announced today the restructuring of their collaboration. Under the original agreement, PTC held commercial rights for the U.S. and Canada and Genzyme held commercial rights in all other countries.

2 Sep 2011

Microtubule stability linked to increased sensitivity to paclitaxel

SCIENTISTS have discovered how blocking key cell signalling proteins could help boost the success rate of the tumour-shrinking drug paclitaxel, according to a study published in the journal Cancer Research today.

2 Sep 2011

Contraceptive pill prevents loss of eye sight

Scientists at University College Cork (UCC) have shown that the active component (Norgestrel) of the contraceptive 'Mini Pill' prevents the loss of sight in mice that have degenerative eye conditions that normally lead to blindness.

2 Sep 2011

New genetic screening program for families at high risk of colorectal cancer

UT Southwestern Medical Center has developed a new lifesaving genetic screening program for families at high risk of contracting colorectal cancer, a deadly yet highly preventable form of cancer.

2 Sep 2011

Pemetrexed treatment produces better outcomes in ALK-translocated NSCLC patients

Patients with ALK-rearranged non-small cell lung cancer (NSCLC) responded significantly better to pemetrexed than patients whose cancer did not show ALK translocation, according to research published in the September issue of the Journal of Thoracic Oncology, the official publication of the International Association for the Study of Lung Cancer.

2 Sep 2011

Genetic News and Research

Researchers discover novel way to increase amounts of antibiotics

Cancer cells with specific genetic defect extra susceptible to therapy that damages DNA

Autism diagnosis by brain scan a possibility

Researchers discover gene mutation linked with lymphoedema, leukaemia

Researchers discover group of mutations involved in T-cell acute lymphoblastic leukemia

Researchers discover new genetic defect that predisposes people to leukemia, myelodysplasia

Scientists sequence ten variants of E. coli O104:H4 outbreak strain across the world

Resveratrol helps prevent metabolic syndrome in offspring

Scientists identify several links between genetic variants and specific metabolic changes

Nature journal publishes Metabolon's genome wide association study

Finland national health institute finds link between H1N1 flu vaccine and children's narcolepsy

Scientists uncover one of the benefits of non-monogamous relationships

Plerixafor drug shows promise against WHIM syndrome

SWOG selects four cancer researchers for 2011 Young Investigator Training Course

More strides against childhood cancer

PTC restructures collaboration with Genzyme

Microtubule stability linked to increased sensitivity to paclitaxel

Contraceptive pill prevents loss of eye sight

New genetic screening program for families at high risk of colorectal cancer

Pemetrexed treatment produces better outcomes in ALK-translocated NSCLC patients

eBook: Using iPSCs models for human disease research and drug discovery eBook

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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