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Study links gut health and brain function in resilient individuals

A new UCLA Health study has found that resilient people exhibit neural activity in the brain regions associated with improved cognition and regulating of emotions, and were more mindful and better at describing their feelings.

21 Jun 2024

Research finds microplastics in human penile tissue

The accumulation of microplastics in penile tissue to determine potential toxicity concerns.

21 Jun 2024

Challenges in treatment of cholangiocarcinoma in patients with primary sclerosing cholangitis

Primary sclerosing cholangitis (PSC) is a rare progressive liver disease that damages bile ducts and significantly increases the risk of bile duct cancer, particularly a type called cholangiocarcinoma (CCA).

20 Jun 2024

Premenopausal oophorectomy reduces white matter integrity in the brain later in life

Women who have their ovaries removed before menopause, particularly before the age of 40, have reduced white matter integrity in multiple regions of the brain later in life.

20 Jun 2024

One copy of the Christchurch variant may confer protection against familial Alzheimer's disease

A scientific story that began with a discovery in just one extraordinary patient is now panning out. In 2019, an international team that included researchers from two Mass General Brigham hospitals -; Mass Eye and Ear and Massachusetts General Hospital (MGH)-; reported on the case of a patient who did not develop cognitive impairment until her late 70s, despite being part of a family at extremely high genetic risk for developing early-onset Alzheimer's disease.

20 Jun 2024

Young adults with periodontitis at higher risk for cryptogenic ischemic stroke

Periodontitis, a common condition, has been linked to a specific type of ischemic stroke.

20 Jun 2024

New cellular atlas revolutionizes understanding of spinal cord injury

Scientists at EPFL have achieved a significant research milestone in the field of spinal cord injuries-;mapping out the cellular and molecular dynamics of paralysis in unprecedented detail with their open-source project 'Tabulae Paralytica'.

19 Jun 2024

Detecting and correcting fMRI distortions caused by arousal fluctuations

In a new study, investigators from McLean Hospital (a member of Mass General Brigham), Harvard Medical School and the National Institute on Drug Abuse – Intramural Research Program (NIDA-IRP) discovered that the tendency of people's arousal to wane over the course of brain scans has been distorting the brain connection maps produced by functional magnetic resonance imaging (fMRI).

19 Jun 2024

Noninvasive heart rate monitoring in chimpanzees using millimeter-wave radar

Measuring the heart rate of great apes in captivity is essential for both health management and animal studies.

19 Jun 2024

Study shows the critical role of time cells in complex behavioral learning

A sense of time is fundamental to how we understand, recall, and interact with the world.

19 Jun 2024

Personalized brain circuit scores define six depression and anxiety biotypes

Researchers used functional magnetic resonance imaging data on brain circuit function to derive interpretable, personalized brain circuit dysfunction scores for patients with anxiety and depression.

19 Jun 2024

Causal variant-targeted ribonucleic acid treatment for congenital melanocytic nevi

A genetic treatment targeting the causal NRAS c.181C>A mutation in congenital melanocytic naevus.

19 Jun 2024

Researchers investigate the gene-brain-behavior link in autism using generative machine learning

Researchers used 3D transport-based morphometry to visualize brain changes linked to 16p11.2 CNV, achieving high prediction accuracy and advancing autism precision medicine.

18 Jun 2024

JACC report card reveals the persistent and tragic inequities in cardiovascular care

As we commemorate Juneteenth 2024, JACC, the flagship journal of the American College of Cardiology, has published "Excess Cardiovascular Mortality Among Black Americans 2000-2022: A Report Card," to highlight the persistent and tragic inequities in cardiovascular care and put in human terms the years of life lost to the Black community because of their higher cardiovascular disease death rates.

18 Jun 2024

New research explores maternal influence on brain biomarkers

A new study by investigators from Mass General Brigham suggests that whether a person inherits risk of Alzheimer's disease from their mother or father influences risk of biological changes in the brain that lead to disease. By evaluating 4,400 cognitively unimpaired adults ages 65-85, the team found those with a history of Alzheimer's disease (AD) on either their mother's side or both parents' sides had increased amyloid in their brains. Their results are published in JAMA Neurology.

18 Jun 2024

Researchers develop cutting-edge smart bandages for improved wound healing

Chronic wounds, which include diabetic ulcers, surgical wounds, pressure injuries, and other problems, are deadlier than many people realize.

17 Jun 2024

Stanford study identifies six depression biotypes for personalized treatment

In the not-too-distant future, a screening assessment for depression could include a quick brain scan to identify the best treatment.

17 Jun 2024

INTEGRA Biosciences announces the appointment of a new board member

INTEGRA Biosciences is excited to welcome Line Stigen Raquet as a non-executive board member.

From INTEGRA Biosciences 17 Jun 2024

AI-based liquid biopsy technology promises early detection of cancer recurrence

An artificial intelligence-powered method for detecting tumor DNA in blood has shown unprecedented sensitivity in predicting cancer recurrence, in a study led by researchers at Weill Cornell Medicine, NewYork-Presbyterian, the New York Genome Center (NYGC) and Memorial Sloan Kettering Cancer Center (MSK).

14 Jun 2024

The hidden genetic switches influencing human height and bone health

In mammals, only 3% of the genome consists of coding genes which, when transcribed into proteins, ensure the biological functions of the organism and the in-utero development of future individuals. But genes do not function alone.

14 Jun 2024