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Study finds link between epimutations in BRCA1 gene and triple-negative breast cancer risk

Research reveals that around 20 per cent of all cases of the most severe form of breast cancer may arise from the small group of normal tissue cells carrying an epimutation of a specific gene.

7 Dec 2023

IDEA trial: Skipping radiotherapy safe for younger postmenopausal patients with early-stage breast cancer

Almost all postmenopausal patients aged 50-69 years with stage I hormone receptor (HR)-positive breast cancer and low scores on a common genetic test who opted out of adjuvant radiotherapy were disease free five years after surgery, according to results from the IDEA clinical trial presented at the San Antonio Breast Cancer Symposium, held December 5-9, 2023.

7 Dec 2023

Candidates clashed but avoided talk of abortion at 4th GOP primary debate

Raised voices and sharp words marked Wednesday night's fourth Republican presidential primary debate as four candidates argued about everything from their own electability to the continued front-runner status of former President Donald Trump. Abortion was never mentioned.

7 Dec 2023

Can oral contraceptive therapy improve the vaginal microbiome in women with PCOS?

The impact of the contraceptive medication-induced change in hormonal levels on the vaginal microbiome.

7 Dec 2023

Associations between low-inflammatory diets and diabetes risk

Associations between a low-inflammatory diet and type 2 diabetes (T2D) risk.

7 Dec 2023

What's my age again? Predicting disease and aging effects by studying organ aging using plasma proteomics data

Researchers performed a proteomic analysis to identify serologic indicators of organ aging and disease.

7 Dec 2023

The association between viral infections and glioma risk

The causal relationship between viral infection and glioma.

7 Dec 2023

Colorado blames Biden team and drugmakers for delaying Canadian imports

Colorado officials say their plan to import cheaper medicines from Canada has been stymied by opposition from drugmakers and inaction by the Biden administration, according to a state report obtained by KFF Health News.

7 Dec 2023

Calcium channel blockers: A new hope for pregnant women with vasospastic angina

A woman with hopes to conceive was diagnosed with severe vasospastic angina (VSA); however, she was able to carry a healthy baby to full term without angina attacks after starting treatment of a calcium channel blocker, according to a case published in a special Cardio-Obstetrics issue of JACC: Case Reports.

6 Dec 2023

PFAS exposure linked to weaker bones in young people

Per- and polyfluoroalkyl substances (PFAS), manufactured chemicals used in products such as food packaging and cosmetics, can lead to reproductive problems, increased cancer risk and other health issues.

6 Dec 2023

Ashwagandha extracts show promise in reducing stress hormones, study suggests

A systematic review reveals that Withania somnifera (Ashwagandha) extracts can effectively reduce cortisol levels in the short term, offering a natural alternative for stress management, though long-term effects remain unexplored.

6 Dec 2023

New research may pave the way for treatment of vaginal yeast infections

New research could one day pave the way for the treatment of vaginal yeast infections, by shedding new light on how microbes in the body absorb zinc.

6 Dec 2023

Thalamus-targeted deep brain stimulation improves cognition in brain injury patients

Study shows that deep brain stimulation (DBS) of the central lateral thalamic nuclei and medial dorsal tegmental tract improves executive function in patients with moderate-severe traumatic brain injury, offering a potential new treatment approach.

6 Dec 2023

Dietary intervention with cooking instructions boosts kidney health in African-Americans, study finds

Study finds that providing fruits, vegetables, and cooking instructions to African-American adults with early-stage chronic kidney disease significantly improves kidney health, highlighting the importance of dietary guidance in disease management.

6 Dec 2023

Blocking an allergy pathway unleashes antitumor immunity in mouse models of non-small cell lung cancer

Researchers at the Icahn School of Medicine at Mount Sinai have identified an allergy pathway that, when blocked, unleashes antitumor immunity in mouse models of non-small cell lung cancer (NSCLC).

6 Dec 2023

Design modifications offer promise for safer and more effective mRNA therapeutics

Researchers have discovered that misreading of therapeutic mRNAs by the cell's decoding machinery can cause an unintended immune response in the body.

6 Dec 2023

Scientists uncover key protein aggregation in frontotemporal dementia

Most neurodegenerative diseases, including dementias, involve proteins aggregating into filaments called amyloids.

6 Dec 2023

Practical guidance for implementing EHR-based chronic disease surveillance

As hospitalizations due to chronic conditions increase across the United States, attention is focusing on using data collected in electronic health records (EHRs) by healthcare systems to enable public health departments to gain understanding of the incidence and prevalence of hypertension, diabetes, asthma, obesity and other chronic diseases with the ultimate goal of improving disease outcomes.

6 Dec 2023

New drug combo fights breast cancer with brain metastases

A combination of two HER2-targeted drugs, tucatinib (Tukysa) and trastuzumab emtansine (Kadcyla, T-DM1), extended progression-free survival among patients with unresectable locally advanced or metastatic HER2-positive breast cancer, compared with T-DM1 alone, according to results from the HER2CLIMB-02 trial presented at the San Antonio Breast Cancer Symposium, held December 5-9, 2023.

6 Dec 2023

Military personnel repeatedly exposed to blasts show increased brain inflammation and structural changes

The brains of special warfare community personnel repeatedly exposed to blasts show increased inflammation and structural changes compared with a control group, potentially increasing the risk of long-term, brain-related disease, according to a new study.

6 Dec 2023

Medicine News and Research

Study finds link between epimutations in BRCA1 gene and triple-negative breast cancer risk

IDEA trial: Skipping radiotherapy safe for younger postmenopausal patients with early-stage breast cancer

Candidates clashed but avoided talk of abortion at 4th GOP primary debate

Can oral contraceptive therapy improve the vaginal microbiome in women with PCOS?

Associations between low-inflammatory diets and diabetes risk

What's my age again? Predicting disease and aging effects by studying organ aging using plasma proteomics data

The association between viral infections and glioma risk

Colorado blames Biden team and drugmakers for delaying Canadian imports

Calcium channel blockers: A new hope for pregnant women with vasospastic angina

PFAS exposure linked to weaker bones in young people

Ashwagandha extracts show promise in reducing stress hormones, study suggests

New research may pave the way for treatment of vaginal yeast infections

Thalamus-targeted deep brain stimulation improves cognition in brain injury patients

Dietary intervention with cooking instructions boosts kidney health in African-Americans, study finds

Blocking an allergy pathway unleashes antitumor immunity in mouse models of non-small cell lung cancer

Design modifications offer promise for safer and more effective mRNA therapeutics

Scientists uncover key protein aggregation in frontotemporal dementia

Practical guidance for implementing EHR-based chronic disease surveillance

New drug combo fights breast cancer with brain metastases

Military personnel repeatedly exposed to blasts show increased brain inflammation and structural changes

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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