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Study shows safety, efficacy of cystic fibrosis drug in children between 1 to 2 years of age

Ann & Robert H. Lurie Children's Hospital of Chicago is one of the study sites in the open label Phase 3 study that showed safety and effectiveness of the cystic fibrosis drug Kalydeco (ivacaftor) in children ages 1 to 2 years.

8 Dec 2017

Prenatal and early-life consumption of sugary drinks may increase risk of mid-childhood asthma

Children between the ages of 7 and 9 may be at greater risk for developing asthma if they consumed high amounts of fructose in early childhood or their mothers drank a lot of sugar-sweetened beverages while pregnant, according to new research published online in the Annals of the American Thoracic Society.

8 Dec 2017

Severely preterm children with HRV have lower airway obstruction linked to retractions, wheezing

Human rhinovirus (HRV), the culprit behind most colds, is the leading cause of hospitalization for premature babies. However, in very preterm children, exactly how HRV causes severe respiratory disease -- and which patients may need more intensive observation and treatment -- is less well understood.

7 Dec 2017

Study: Traffic-related air pollutants appear to thwart benefits of walking among older adults

Even short-term (2 hour) exposure to tiny particles of soot or dust found in traffic fumes on busy roads appears to thwart the benefits of walking on the heart and lungs among older adults (aged 60 or over), according to a study comparing the health effects of walking along a traffic-polluted road versus walking through a park.

7 Dec 2017

Scientists reveal ‘anti-metastatic surveillance’ role of Caveolin-1 protein

A new study conducted at the VIB-KU Leuven Center for Cancer Biology in Belgium has labeled the protein Caveolin-1 as a high-potential pursuit in the fight against cancer.

5 Dec 2017

FDA grants approval to first biosimilar for treatment of patients with breast, stomach cancers

The U.S. Food and Drug Administration today approved Ogivri (trastuzumab-dkst) as a biosimilar to Herceptin (trastuzumab) for the treatment of patients with breast or metastatic stomach cancer (gastric or gastroesophageal junction adenocarcinoma) whose tumors overexpress the HER2 gene (HER2+).

4 Dec 2017

Novel drug combination could enhance immunotherapy responses in patients with lung cancer

Johns Hopkins Kimmel Cancer Center researchers and colleagues have identified a novel drug combination therapy that could prime nonsmall cell lung cancers to respond better to immunotherapy.

30 Nov 2017

Length of stay in ICU may have impact on preterm babies’ behavior

A study conducted by researchers at the University of São Paulo's Ribeirão Preto School of Medicine in Brazil, with support from the Sao Paulo Research Foundation - FAPESP , indicates that length of stay in the ICU is the factor that best explains some preterm babies' behavioral problems relating to emotional regulation, regardless of the degree of prematurity and the presence of bronchopulmonary dysplasia and retinopathy of prematurity (ROP).

30 Nov 2017

Underground transit routes expose passengers to greater concentrations of carcinogens, study finds

According to the U.S. Census Bureau, nearly 90 percent of the 4.5 million workers in the Los Angeles area spend an average of 60 minutes each day commuting on a roadway or railway.

30 Nov 2017

Regular exercise may protect smokers from muscle loss and inflammation

Regular exercise may protect smokers from some of the negative effects associated with smoking, such as muscle loss and inflammation, according to a new study.

28 Nov 2017

Treatment with endogenous protein can heal scarring in the lungs

The endogenous protein RAGE, which has usually been negatively associated with chronic inflammation and diabetic complications, plays a major role in the repair of DNA damage - and also appears to heal tissue damaged as a result of accelerated cell senescence.

27 Nov 2017

Scientists detect pathological prion protein in skin of CJD patients

Researchers have found that it was possible to detect abnormal prion protein in the skin of 23 people who died from Creutzfeldt-Jakob Disease (CJD). They also found that exposing mice to skin tissue taken from the CJD patients caused them to develop prion disease.

23 Nov 2017

Low levels of miR-29 could reduce susceptibility to cardiac fibrosis

Cardiac fibrosis involves an increase of connective tissue in the cardiac muscle, causing a loss of function. A team of researchers at the Technical University of Munich has now discovered that microRNA 29 (miR-29) plays an important role in the formation of tissue fibrosis.

23 Nov 2017

SITC releases first consensus recommendations on managing immunotherapy side effects

The first consensus recommendations on recognition and clinical management of immune-related side effects from cancer immunotherapy are published today in the Journal for ImmunoTherapy of Cancer.

22 Nov 2017

Multiple sclerosis drug can beat obstinate bacteria

Encountering bacteria with innocent names such as Pseudomonas aeruginosa and Enterobacteriaceae can lead to hospitalization and - in a worst-case scenario - can also be life-threatening. The bacteria, which cause infections such as pneumonia, frequently develop multi-resistance towards classic antibiotics.

22 Nov 2017

Inflammatory processes triggered by lung cancer could cause pulmonary hypertension

Shortness of breath and respiratory distress often increase the suffering of advanced-stage lung cancer patients. These symptoms can be triggered by pulmonary hypertension, as scientists at the Max Planck Institute for Heart and Lung Research in Bad Nauheim and the German Center for Lung Research found after examining more than 500 patients.

22 Nov 2017

CF patients in the U.S. show faster rate of improvement in lung function and nutrition

New research comparing cystic fibrosis patients in the United States and Canada showed that, although the patients' nutritional status and lung function improved in both countries over the period from 1990 to 2013, the rate of improvement was faster in the United States.

22 Nov 2017

Controlling organ functions with your cell phone may be possible in future

Think about this. You have diabetes, are trying to control your insulin levels and instead of taking a pill or giving yourself an injection, you click an app on your phone that tells your pancreas to bring blood sugar levels back to normal.

22 Nov 2017

Biologists reveal how bacterial cells thrive in oxygen-poor environments

Columbia University biologists have revealed a mechanism by which bacterial cells in crowded, oxygen-deprived environments access oxygen for energy production, ensuring survival of the cell. The finding could explain how some bacteria, such as Pseudomonas aeruginosa (P. aeruginosa), are able to thrive in oxygen-poor environments like biofilms and resist antibiotics.

21 Nov 2017

Researchers compare shunts and stents to maintain blood flow in infants with heart disease

Infants with various forms of congenital heart disease require a stable source of blood flow to their lungs in order to survive until a more definitive operation can be performed. In a recent study, pediatric researchers compared two methods to provide that flow: a shunt to reroute blood and an implanted stent to maintain an open path for blood flow.

21 Nov 2017

Lungs News and Research

Study shows safety, efficacy of cystic fibrosis drug in children between 1 to 2 years of age

Prenatal and early-life consumption of sugary drinks may increase risk of mid-childhood asthma

Severely preterm children with HRV have lower airway obstruction linked to retractions, wheezing

Study: Traffic-related air pollutants appear to thwart benefits of walking among older adults

Scientists reveal ‘anti-metastatic surveillance’ role of Caveolin-1 protein

FDA grants approval to first biosimilar for treatment of patients with breast, stomach cancers

Novel drug combination could enhance immunotherapy responses in patients with lung cancer

Length of stay in ICU may have impact on preterm babies’ behavior

Underground transit routes expose passengers to greater concentrations of carcinogens, study finds

Regular exercise may protect smokers from muscle loss and inflammation

Treatment with endogenous protein can heal scarring in the lungs

Scientists detect pathological prion protein in skin of CJD patients

Low levels of miR-29 could reduce susceptibility to cardiac fibrosis

SITC releases first consensus recommendations on managing immunotherapy side effects

Multiple sclerosis drug can beat obstinate bacteria

Inflammatory processes triggered by lung cancer could cause pulmonary hypertension

CF patients in the U.S. show faster rate of improvement in lung function and nutrition

Controlling organ functions with your cell phone may be possible in future

Biologists reveal how bacterial cells thrive in oxygen-poor environments

Researchers compare shunts and stents to maintain blood flow in infants with heart disease

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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