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Gene screen patent brings 2007 Deal of Distinction Award to UChicagoTech

UChicagoTech, the University of Chicago's Office of Technology and Intellectual Property, has received a 2007 Deal of Distinction Award from the Licensing Executives Society of U.S.A. and Canada.

29 Oct 2007

Possible biomarker for colon cancer in people under 50

An abnormality of chromosomes long associated with diseases of aging has, for the first time, been linked to colon cancer in people 50 years old and younger, an age group usually considered young for this disease.

28 Oct 2007

Possible biomarker for colon cancer in people 50 and under

28 Oct 2007

Emerging cancer therapies and novel targets

What are the cancer drugs of tomorrow and how will they be developed? At the AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics, researchers will present some answers to these and other pressing questions regarding emerging cancer therapeutics.

25 Oct 2007

Potent inhibitor of Kinesin CENP-E demonstrates tumor cell inhibition

A first-in-class, targeted investigational therapy specifically designed to inhibit a single protein that functions only during cell division shows potent activity in a broad range of cancer cell lines, say researchers from GlaxoSmithKline.

24 Oct 2007

Experimental cancer pharmaceuticals under trial

A potent and selective inhibitor of the mitotic kinesin CENP-E (GSK923295A) demonstrates a novel mechanism of inhibiting tumor cell proliferation and shows activity against a broad panel of human tumor cell lines in vitro: Abstract A 111.

24 Oct 2007

Advances in drug screening

With the discovery of suitable molecular targets - cellular molecules along pathways crucial for sustaining the life of cancer cells - comes the perplexing dilemma of where to find the next therapeutics that will bind to and disable those targets.

23 Oct 2007

Health Discovery receives notice of allowance of U.S. patent application covering kernel selection methods

Health Discovery Corporation has announced that the U.S. Patent and Trademark Office has issued a notice of allowance of HDC's patent application covering methods for selection of kernels, i.e., functions or algorithms that are used to transform input data into a different configuration, known as "feature space", which allows for easier recognition of patterns within the data.

18 Oct 2007

First colonoscopy a real lifesaver

The scientists from Memorial Sloan-Kettering Cancer Center's department of epidemiology and biostatistics in New York City, say this first clean out of precancerous polyps significantly reduces deaths from colon cancer even if there are no follow-up examinations.

17 Oct 2007

African-Americans have a high overall incidence of colorectal cancer - study emphasizes importance of screening

New research presented at the 72nd Annual Scientific Meeting of the American College of Gastroenterology emphasizes the importance of colorectal cancer (CRC) screening among racial and ethnic minorities, who have a higher incidence of colorectal cancer compared to Caucasians.

16 Oct 2007

New analyses of long-term LIALDA (mesalamine) data presented at ACG

Post-hoc and other analyses of secondary endpoints of a long-term safety and tolerability study of Shire plc's ulcerative colitis (UC) drug LIALDA (mesalamine) provide further data on LIALDA in patients with mild to moderate ulcerative colitis.

16 Oct 2007

First colonoscopy with removal of polyps linked to reduction in colon cancer death

Using a model to predict reductions in death from colorectal cancer, epidemiologists and clinical researchers from Memorial Sloan-Kettering looked at the relative effect of an initial screening colonoscopy which clears pre-cancerous polyps from the colon versus surveillance follow-up colonoscopy.

16 Oct 2007

Colorectal cancer screening improves survival in seniors

As people get older, their risk of developing polyps and colorectal cancer increases. Currently, there is no clear evidence or established guideline for the upper age limit for colorectal cancer screening by colonoscopy.

16 Oct 2007

Genome update defines landscape of breast and colon cancers

One year after completing the first large-scale report sequencing breast and colon cancer genes, Johns Hopkins Kimmel Cancer Center scientists have studied the vast majority of protein-coding genes which now suggest a landscape dominated by genes that each are mutated in relatively few cancers.

12 Oct 2007

Analysis of breast and colon cancer genes finds 5,000 previously unmapped genes

Researchers from University Hospitals (UH) Ireland Cancer Center and Case Western Reserve University School of Medicine are part of a new national study that has analyzed more than 18,000 genes, including 5,000 previously unmapped genes, from breast and colorectal tumors.

12 Oct 2007

Efficiency and safety of endoscopic treatment of gastrointestinal smooth muscle tumors

Gastrointestinal smooth muscle tumors (SMTs, including leiomyoma and leiomyosarcoma) represent relatively common lesions that are thought to originate from a muscular layer of the gastrointestinal tract.

10 Oct 2007

Public misled and confused about exercise

The researchers from Exeter and Brunel Universities found in a survey of nearly 1,200 people that half of the men and three quarters of the women involved thought moderate exercise conferred the greatest health benefits.

10 Oct 2007

Interleukin-8, key marker for colorectal cancer treatment

Colorectal cancer (CRC) is currently one of the three most frequent malignancies in Western industrial nations.

10 Oct 2007

Tiny radioactive molecules provide novel way to fight colorectal cancer

Johns Hopkins scientists have developed a potentially novel way to fight colorectal cancer using tiny molecules to deliver potent barrages of radiation inside cancer cells, unlike current treatments that bind to the surface of cells and attack from the outside and cause unwanted side effects.

10 Oct 2007

Xeloda (capecitabine) better all round for cancer patients

A drug to treat colon cancer is proving much more convenient than traditional chemotherapy, has fewer side effects - and a study of almost 2,000 patients has shown it is giving them a better chance of surviving the disease.

9 Oct 2007