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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Novel antibody-drug conjugate shows 29% response rate in rare blood cancer

Early study data shows a 29% overall response rate, the favorable safety profile in blastic plasmacytoid dendritic cell neoplasm (BPDCN)

8 Dec 2020

Dihydrogen phosphate anions bind together even in dilute solutions, study shows

Scientists at UNSW Sydney, together with collaborators from Western Sydney University and The Netherlands, were surprised to find that dihydrogen phosphate anions - vital inorganic ions for cellular activity - bind with other dihydrogen phosphate anions despite being negatively charged.

8 Dec 2020

Study elucidates the link between oxytocin gene methylation and parental empathy

Parenting behavior is deeply linked to the ability to empathize with one’s children. Thus, to better understand why certain parents react to certain situations in a certain way, it is crucial to gain insight into how empathy is shaped.

8 Dec 2020

RNA mutations within common bacterium linked to invasive meningococcal disease

Researchers at Karolinska Institutet in Sweden have come one step closer toward understanding why some people become seriously ill or die from a common bacterium that leaves most people unharmed.

7 Dec 2020

Testing for tumor DNA can help predict risk of relapse after transplant in DLBCL patients

Many patients with diffuse large B-cell lymphoma (DLBCL) can be cured by a transplant using their own blood-forming stem cells, but as many as half eventually relapse.

7 Dec 2020

Monash researchers isolate high-quality sperm using acoustic waves

Monash University researchers have combined acoustic waves and fluid dynamics to create a new approach for separating high-quality sperm in assisted reproduction - opening new windows for infertile couples to have a family of their own.

7 Dec 2020

Study assesses different pipelines for timing mutations in cancer genomes

UCLA Jonsson Comprehensive Cancer Center researchers studying cancer evolution have created a framework to help determine which tool combinations are best for pinpointing the exact timing of DNA mutations in cancer genomes.

7 Dec 2020

Study reveals genetic abnormalities that cause brain aneurysms

Nearly three percent of the world's population is at risk of developing an intracranial aneurysm, a localized dilation of a blood vessel forming a fragile pocket. Rupture of this aneurysm results in extremely severe, and, in one-third of cases, fatal hemorrhage.

7 Dec 2020

Topoisomerase 1 inhibition prevents SARS-CoV-2-induced inflammation and death in animal models

A new study indicates that the topoisomerase 1 (Top1) is intimately related to the lethal inflammation associated with SARS-CoV-2 infection in a large proportion of cases.

7 Dec 2020

Study identifies multiple important genomic differences in BCL malignancies using genomic ancestry

B-cell lymphoma and leukemias (BCL) are a diverse set of malignancies. While the genomic landscape of many BCL subtypes has been described, genomic ancestry has rarely been explored.

6 Dec 2020

Researchers recommend strategies for improving the accuracy of polygenic risk scores

As the consumer genetics industry rapidly expands, more and more people are turning to DNA-based services to learn their risk of developing a wide range of diseases.

5 Dec 2020

CRISPR-based test could provide rapid, low-cost testing to help control COVID-19 spread

Imagine swabbing your nostrils, putting the swab in a device, and getting a read-out on your phone in 15 to 30 minutes that tells you if you are infected with the COVID-19 virus.

5 Dec 2020

Lung tissue analysis reveals promising molecular target to ameliorate pulmonary fibrosis

An analysis of lung tissues from patients with different types of pulmonary fibrosis - including cases triggered by COVID-19 - has revealed a promising molecular target to ameliorate the chronic and irreversible disease.

5 Dec 2020

Study finds surprising link between ALS, FTD and Huntington's disease-associated mutation

A study led by researchers at the National Institutes of Health has made a surprising connection between frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS), two disorders of the nervous system, and the genetic mutation normally understood to cause Huntington's disease.

5 Dec 2020

Researchers develop a promising fix to CRISPR-Cas9's unwanted changes problem

A group of researchers developed a promising fix to CRISPR-Cas9's problem with unwanted genetic changes using a method that allows them to turn off gene-editing until it reaches key cell cycle phases where more accurate repairs are likely to happen.

4 Dec 2020

New CRISPR-Cas9 variant improves efficiency of gene editing tool

Using a new variant to repair DNA will improve both safety and effectiveness of the much-touted CRISPR-Cas9 tool in genetic research, Michigan Medicine researchers say.

3 Dec 2020

TTUHSC professor receives 2020 Lupus Mechanisms and Targets Award

The Lupus Research Alliance recently named R. Bryan Sutton, Ph.D., a professor in the Department of Cell Physiology and Molecular Biophysics at the Texas Tech University Health Sciences Center, as a recipient of a 2020 Lupus Mechanisms and Targets Award.

3 Dec 2020

Guidelines for accurate amplicon-based sequencing of SARS-CoV-2

A new study describes much-needed guidelines for reliable viral sequencing, validated in a large group of clinical samples.

3 Dec 2020

Scientists develop new bioinformatics pipeline to identify viruses in environmental samples

Researchers from the University of Helsinki have developed a novel bioinformatics pipeline called Lazy pipe for identifying viruses in host-associated or environmental samples.

3 Dec 2020

GoMo Health EarlyCare program nurtures prenatal, postnatal moms to address psychological health

GoMo Health and the Center for BrainHealth® at The University of Texas at Dallas have joined forces to incorporate the Center's research-backed strategies that enhance brain health and build resilience, into GoMo Health's evidence-based patient engagement platform.

3 Dec 2020

DNA News and Research

Further Reading

Novel antibody-drug conjugate shows 29% response rate in rare blood cancer

Dihydrogen phosphate anions bind together even in dilute solutions, study shows

Study elucidates the link between oxytocin gene methylation and parental empathy

RNA mutations within common bacterium linked to invasive meningococcal disease

Testing for tumor DNA can help predict risk of relapse after transplant in DLBCL patients

Monash researchers isolate high-quality sperm using acoustic waves

Study assesses different pipelines for timing mutations in cancer genomes

Study reveals genetic abnormalities that cause brain aneurysms

Topoisomerase 1 inhibition prevents SARS-CoV-2-induced inflammation and death in animal models

Study identifies multiple important genomic differences in BCL malignancies using genomic ancestry

Researchers recommend strategies for improving the accuracy of polygenic risk scores

CRISPR-based test could provide rapid, low-cost testing to help control COVID-19 spread

Lung tissue analysis reveals promising molecular target to ameliorate pulmonary fibrosis

Study finds surprising link between ALS, FTD and Huntington's disease-associated mutation

Researchers develop a promising fix to CRISPR-Cas9's unwanted changes problem

New CRISPR-Cas9 variant improves efficiency of gene editing tool

TTUHSC professor receives 2020 Lupus Mechanisms and Targets Award

Guidelines for accurate amplicon-based sequencing of SARS-CoV-2

Scientists develop new bioinformatics pipeline to identify viruses in environmental samples

GoMo Health EarlyCare program nurtures prenatal, postnatal moms to address psychological health

eBook: Exploring the Cell Cycle and DNA Damage and Repair eBook

Leveraging the power of automation to boost research

Automating research - solutions and best practices

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