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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

UV light induces new types of DNA damage that may cause malignant melanoma

Studies conducted in yeast show that exposure to ultraviolet light (UV) induces new types of DNA damage that may cause the deadliest form of skin cancer, malignant melanoma.

17 Nov 2020

Novel mechanism enhances the formation of hematopoietic stem cells

Hematopoietic stem cells can replenish all the different cell types of our blood system. For this reason, hematopoietic stem cells are the cells used in many blood diseases when patients need transplantations.

17 Nov 2020

CMU researchers develop new technique for isolating brain cells associated with Parkinson's disease

Carnegie Mellon University researchers have developed a new technique for isolating a type of brain cell associated with Parkinson's disease symptoms, enabling them to study that cell type in detail.

16 Nov 2020

Sanger Institute and COG-UK get £12.2M funding to build genomic surveillance system for COVID-19

The Department for Health and Social Care Testing Innovation Fund has backed the Wellcome Sanger Institute and the COVID-19 Genomics UK Consortium in expanding whole genome sequencing of positive SARS-CoV-2 virus samples to map how COVID-19 spreads and evolves.

16 Nov 2020

Nanobodies: unharnessed potential in COVID-19 treatment

A new study published in the Journal of Biomolecular Structure and Dynamics in October 2020 discusses the use of nanobodies in diagnosing and treating this deadly disease.

16 Nov 2020

UCLA Health collaborates with Regeneron Genetics Center to bring genomic medicine to patients

UCLA Health has entered into a collaborative research agreement with the Regeneron Genetics Center (RGC) to provide whole exome sequencing for 150,000 UCLA Health patients.

16 Nov 2020

Study reveals 3D structure of key phage component in atomic resolution

Given that phages are able to destroy bacteria, they are of particular interest to science. Basic researchers from the Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) in Berlin are especially interested in the tube used by phages to implant their DNA into bacteria.

16 Nov 2020

Immunotherapy combination shrinks rare angiosarcoma tumors in 25% of patients

Researchers from SWOG Cancer Research Network, a cancer clinical trials group funded by the National Cancer Institute's Division of Cancer Diagnosis and Treatment, part of the National Institutes of Health, have shown that the immunotherapy combination of ipilimumab and nivolumab shrinks rare angiosarcoma tumors in 25 percent of all patients, with some having an even stronger response to the drug combination.

15 Nov 2020

New model can predict the risk of adverse side effects of cancer treatment

The risk of serious adverse effects on the blood status and bone marrow of patients during chemotherapy can be predicted by a model developed at Linköping University, Sweden.

12 Nov 2020

Comparison of 240 mammal genomes helps geneticists to identify disease mutations

A large international consortium led by scientists at Uppsala University and the Broad Institute of MIT and Harvard has sequenced the genome of 130 mammals and analyzed the data together with 110 existing genomes to allow scientist to identify which are the important positions in the DNA.

11 Nov 2020

Researchers uncover potential genetic target for treating endometriosis

Michigan State University researchers have identified a potential genetic target for treating an especially painful and invasive form of endometriosis.

11 Nov 2020

Spike-based DNA vaccine shows excellent protection against SARS-CoV-2 in a hamster model

A study conducted at the United States Army Research Institute of Infectious Diseases shows how a relatively simple full-length DNA vaccine against spike glycoprotein of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can elicit neutralizing antibody response in an animal model – even after a single shot with simple jet injection technique.

11 Nov 2020

IU researcher awarded NCI grant to develop a drug for making radiation therapy more effective

An Indiana University Melvin and Bren Simon Comprehensive Cancer Center researcher has been awarded a five-year, $2.9 million grant from the National Cancer Institute to develop a drug that could make radiation therapy far more effective.

11 Nov 2020

Study indicates the role of Polβ enzyme in cognitive development

It's a fact of life that things break down. And when they do, whether it's your car, the roof, or a blocked artery, there are people who we can call to help with the repairs.

11 Nov 2020

Study may lead to new therapies that accelerate removal of cellular debris from the brain

Microglia -- the brain's immune cells -- play a primary role in removing cellular debris from the brain. According to a recent study by a Nagoya University-led research team in Japan, another kind of brain cell, called astrocyte, is also involved in removing debris as a backup to microglia.

11 Nov 2020

Single clinical laboratory test can rapidly detect serious infections

UC San Francisco scientists have developed a single clinical laboratory test capable of zeroing in on the microbial miscreant afflicting patients hospitalized with serious infections in as little as six hour.

11 Nov 2020

A promising vaccine for treating poorly immunogenic tumors

Patients with cancer have multiple treatment options available to them today, but each has its drawbacks. Chemotherapy kills rapidly dividing cancer cells, but it also damages healthy cells in the body and often does not effectively prevent tumor metastasis or disease recurrence.

11 Nov 2020

How SARS-CoV-2 blocks immune response

An international research team has confirmed the mechanism by which the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus disease 2019 (COVID-19). Their article titled, “SARS-CoV-2 Orf6 hijacks Nup98 to block STAT nuclear import and antagonize interferon signaling,” is published in the journal Proceedings of the National Academy of Sciences.

11 Nov 2020

Lowest risk for autism associated with mid-levels of immune marker measured at birth

The causes of autism spectrum disorder (ASD) - including genetic and environmental factors - are not entirely understood. Many studies have already shown that serious maternal infection during pregnancy is associated with increased risk for offspring in both people and animals.

10 Nov 2020

Study uncovers mechanisms behind premature menopause's link to cardiovascular disease

Menopause that occurs before a woman is 40 years old accelerates aging and is a risk factor for cardiovascular disease.

10 Nov 2020

DNA News and Research

Further Reading

UV light induces new types of DNA damage that may cause malignant melanoma

Novel mechanism enhances the formation of hematopoietic stem cells

CMU researchers develop new technique for isolating brain cells associated with Parkinson's disease

Sanger Institute and COG-UK get £12.2M funding to build genomic surveillance system for COVID-19

Nanobodies: unharnessed potential in COVID-19 treatment

UCLA Health collaborates with Regeneron Genetics Center to bring genomic medicine to patients

Study reveals 3D structure of key phage component in atomic resolution

Immunotherapy combination shrinks rare angiosarcoma tumors in 25% of patients

New model can predict the risk of adverse side effects of cancer treatment

Comparison of 240 mammal genomes helps geneticists to identify disease mutations

Researchers uncover potential genetic target for treating endometriosis

Spike-based DNA vaccine shows excellent protection against SARS-CoV-2 in a hamster model

IU researcher awarded NCI grant to develop a drug for making radiation therapy more effective

Study indicates the role of Polβ enzyme in cognitive development

Study may lead to new therapies that accelerate removal of cellular debris from the brain

Single clinical laboratory test can rapidly detect serious infections

A promising vaccine for treating poorly immunogenic tumors

How SARS-CoV-2 blocks immune response

Lowest risk for autism associated with mid-levels of immune marker measured at birth

Study uncovers mechanisms behind premature menopause's link to cardiovascular disease

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