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New mechanism that initiates metastasis

Researchers have known for years that the enzyme MMP-9 plays a key role in the spread of colorectal cancer. Now, scientists at Jefferson Medical College in Philadelphia have found out how the enzyme helps initiate the process, known as metastasis.

4 Apr 2006

Regular use of COX-2 inhibitors may reduce the risk of breast cancer

Results from a new, five-year study show that regular use of popular prescription pain relievers may reduce the risk of breast cancer by up to 71 percent and may offer similar benefit in the prevention of prostate, colon and lung cancers.

4 Apr 2006

Mayo Clinic discover cellular secret that may explain how certain cancers move and spread

If the mechanism that drives cancer movement - also called metastasis - can be understood well enough to manipulate it, new and better treatments can be developed for patients with metastatic cancers.

4 Apr 2006

Scientists identify a new gene that causes the spread of cancer

Professor Philip Rudland, Dr Guozheng Wang and Dr Roger Barraclough from the University’s Cancer and Polio Research Fund Laboratories have discovered an additional member of the S100 family of protein genes - S100P - that causes the spread of cancerous cells from an original tumour to other parts of the body.

30 Mar 2006

Earlier onset of colorectal cancer associated with alcohol use, tobacco use and male gender

Colorectal cancer is the second leading cause of cancer death in the United States yet it is one of the most preventable forms of the disease.

28 Mar 2006

Medicinal properties in mahogany bark may hold colon cancer cure

U of So. Carolina cancer researcher Dr. Michael Wargovich is studying whether medicinal properties in the bark of mahogany trees may hold clues to understanding colon cancer.

27 Mar 2006

Swedish scientists move closer to a cancer vaccine

Scientists at Karolinska Institutet in Sweden have helped to identify a molecule that can be used as a vaccination agent against growing cancer tumours. Although the results are so far based on animal experiments, they point to new methods of treating metastases.

21 Mar 2006

New research suggests it may be possible to separate the anticancer properties of vitamin D

At the right dose, vitamin D is important for bone development and may help protect against the development of several cancers, particularly colorectal cancer.

21 Mar 2006

African American women urged to confront colorectal cancer

Despite having the greatest risk of developing and dying from colorectal cancer (CRC) of any gender, race or ethnicity, an astounding 96 percent of African American women do not consider themselves to be at high risk for the disease, according to a new Harris poll.

17 Mar 2006

Studying the gene-expression profiles of patients with colorectal cancer might help predict their response to chemotherapy

Studying the gene-expression profiles of patients with colorectal cancer might help predict their response to chemotherapy.

15 Mar 2006

Man-made chemical compound targets and kills tumor cells

A man-made chemical compound called ARC causes tumor cells to die but leaves normal cells unharmed, researchers at the University of Illinois at Chicago report in a study highlighted in the March 15 issue of Cancer Research.

15 Mar 2006

New test for detecting small amounts of proteins in the blood

Researchers at the University of Pennsylvania School of Medicine have developed a paradigm-shifting method for detecting small amounts of proteins in the blood.

13 Mar 2006

Data from Novogen inflammatory bowel disease drug Phase I clinical trial shows promise

A recently completed Phase 1 clinical trial of an investigational drug to treat inflammatory bowel disease has demonstrated rapid absorption indicating potential for development as an oral therapy.

6 Mar 2006

FDA gives greenlight for new treatment of head and neck cancer

The U.S. Food and Drug Administration has approved colon cancer drug Erbitux to treat head and neck cancer after results of a large clinical trial showed the drug prolonged survival by 20 months.

5 Mar 2006

Hepatic arterial infusion versus systemic therapy for hepatic metastases from colorectal cancer

A new study shows that patients whose colorectal cancer has spread to the liver who received an approach called hepatic arterial infusion (HAI) - the administration of chemotherapy directly to the liver through a pump in the abdomen - fare better than those who received traditional, intravenous chemotherapy.

1 Mar 2006

Ginkgo biloba reduces aggressive cancer risk in animal experiments

Researchers at Georgetown University Medical Center say they now have a clearer picture of how an extract from the leaves of the Ginkgo biloba tree reduces the risk of aggressive cancer in animal experiments.

27 Feb 2006

Doctors fail to recommend colon cancer tests for low-income patients

Fewer than nine out of 10 low-income, medically underserved minority patients at risk for colorectal cancer receive a recommendation for colorectal cancer screening by physicians at government-supported community health centers

24 Feb 2006

M. D. Anderson Cancer Center to investigate CTCE-9908 chemokine CXCR4 antagonist

Chemokine Therapeutics has announced that it has entered into an agreement with The University of Texas M. D. Anderson Cancer Center of Houston, Texas to study the Company's lead anti-cancer compound, CTCE-9908, a chemokine CXCR4 antagonist.

21 Feb 2006

Mangafodipir appears to increase the cancer-killing ability of some chemotherapy drugs

A contrast agent currently used in magnetic resonance imaging (MRI), called mangafodipir, may increase the cancer-killing ability of some chemotherapy drugs while protecting normal cells, according to a study in the Journal of the National Cancer Institute.

21 Feb 2006

New mechanism that regulates K-Ras - protein that plays an important role in cancer

Researchers have discovered a protein widely known to cause the out-of-control growth of cells can actually be manipulated to induce those cells to commit suicide, providing a novel target for the development of anti-cancer drugs, according to the results of a new study led by New York University School of Medicine researchers.

21 Feb 2006

Colon News and Research

New mechanism that initiates metastasis

Regular use of COX-2 inhibitors may reduce the risk of breast cancer

Mayo Clinic discover cellular secret that may explain how certain cancers move and spread

Scientists identify a new gene that causes the spread of cancer

Earlier onset of colorectal cancer associated with alcohol use, tobacco use and male gender

Medicinal properties in mahogany bark may hold colon cancer cure

Swedish scientists move closer to a cancer vaccine

New research suggests it may be possible to separate the anticancer properties of vitamin D

African American women urged to confront colorectal cancer

Studying the gene-expression profiles of patients with colorectal cancer might help predict their response to chemotherapy

Man-made chemical compound targets and kills tumor cells

New test for detecting small amounts of proteins in the blood

Data from Novogen inflammatory bowel disease drug Phase I clinical trial shows promise

FDA gives greenlight for new treatment of head and neck cancer

Hepatic arterial infusion versus systemic therapy for hepatic metastases from colorectal cancer

Ginkgo biloba reduces aggressive cancer risk in animal experiments

Doctors fail to recommend colon cancer tests for low-income patients

M. D. Anderson Cancer Center to investigate CTCE-9908 chemokine CXCR4 antagonist

Mangafodipir appears to increase the cancer-killing ability of some chemotherapy drugs

New mechanism that regulates K-Ras - protein that plays an important role in cancer

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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