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Gene fusion appears to cause prostate cancer

Scientists at the University of Michigan Medical School, in collaboration with researchers at Harvard's Brigham and Women's Hospital, have discovered a recurring pattern of scrambled chromosomes and abnormal gene activity that occurs only in prostate cancer.

30 Oct 2005

Lack of gene expression associated with ovarian cancer

The expression of two specific genes is almost completely downregulated in ovarian cancer tumours. An extensive analysis of gene expression in ovarian cancer tumour cells has revealed this important finding, which should be an aid to early diagnosis.

24 Oct 2005

Yeast cells help show how GSAO (glutathionarsenoxide) angiogenesis inhibitor drug works

The humble yeast has revealed the molecular workings of an anti-cancer drug that stops the growth and spread of tumours in humans by starving their blood supply.

18 Oct 2005

Cosmopolitan Lifestyle could allay cancer threat

If the cancer-inhibiting properties of red wine don't tempt you, why not try a cosmopolitan, the cranberry-based cocktail made famous by the Sex and the City girls.

17 Oct 2005

Computer-assisted instruction offers the potential to overcome knowledge barriers and improve screening rates

Even patients with minimal education and no computer skills can be successfully educated about health topics using computers, according to new research at Wake Forest University Baptist Medical Center.

16 Oct 2005

CT colonography best choice for regular screening for cancer

Colorectal cancer is the second leading cause of cancer deaths in most developed countries. Screening for colorectal malignancies and polyps (which frequently become cancerous) has been shown to lower the number of deaths from cancer. Most cancer societies and preventive task forces recommend regular screening for cancer of the colon.

10 Oct 2005

Long-term use of NSAIDs cuts the risk for oral cancer in smokers by half but increases risk of cardiovascular problems

An analysis of 20 years of data on the health of over 900 adults has found that long-term use of traditional nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen and naproxen, cuts the risk for oral cancer in smokers by half.

9 Oct 2005

Gene variation may play fundamental role in the development and spread of cancer in the body

New research shows that a small gene variation that increases the risk of inherited cancer can also arise during the development of spontaneous, or non-inherited, tumors.

9 Oct 2005

Gut antibody could prove to be a promising drug target for Crohn's disease

A collaboration led by the Burnham Institute for Medical Research has found that an antibody which binds to an unusual sugar molecule residing in the gut halts the inflammation seen in Crohn's disease and other intestinal inflammations. The antibody could prove to be a promising drug target for these common chronic intestinal disorders.

9 Oct 2005

Cancer incidence among women has increased slightly

Overall rates of cancer death for both men and women have declined in the United States, and cancer incidence has remained stable among men. However, overall cancer incidence among women has increased slightly, according to a special article that appears in the October 5 issue of the Journal of the National Cancer Institute.

4 Oct 2005

Americans' risk of dying from cancer continues to decline

The nation's leading cancer organizations report that Americans' risk of dying from cancer continues to decline and that the rate of new cancers is holding steady. The "Annual Report to the Nation on the Status of Cancer, 1975-2002," published in the Oct. 5, 2005, issue of the Journal of the National Cancer Institute, shows observed cancer death rates from all cancers combined dropped 1.1 percent per year from 1993 to 2002.

4 Oct 2005

Common cancer susceptibility gene appears to be frequently acquired in metastatic lesions from colorectal cancer

A relatively common cancer susceptibility gene appears to be frequently acquired in metastatic lesions from colorectal cancer, and give cancer cells a growth advantage, according to a study in the October 5 issue of JAMA: The Journal of the American Medical Association.

4 Oct 2005

Researchers identify gene defect in mice that causes cyclical hair loss and skin cancer

Researchers at Jefferson Medical College and at the Wadsworth Center in New York have identified a gene defect in mice resulting in a range of abnormalities, from cyclical hair loss and skin cancer to severe problems in normal skin development.

4 Oct 2005

Behavior-based means of cutting the risks of tobacco

Three researchers who study behavior-based means of cutting the risks of tobacco use have made a case for counseling patients about the health risks of exposure to secondhand smoke when they're asked about direct tobacco use.

3 Oct 2005

Pursuit of potential drugs and small molecules that target the IGF-1 receptor

Pharmaceutical companies around the world still come knocking on Renato Baserga, M.D.,'s door. And for good reason.

27 Sep 2005

Researchers at Johns Hopkins have identified three new genetic mutations in brain tumors

...a discovery that could pave the way for more effective cancer treatments.

27 Sep 2005

Change in gene may be underlying molecular defect in some colorectal cancers

Inactivation of a DNA repair gene may be an early step in the development of sporadic colorectal tumors, and detection of the molecular basis for this inactivation may ultimately be useful in risk assessment for colorectal cancer, according to a new study in the current issue of the Journal of the National Cancer Institute.

22 Sep 2005

Next generation of effective viral-based therapies for cancer

Researchers at Columbia University Medical Center continue to make strides in their work to develop the next generation of effective viral-based therapies for cancer.

21 Sep 2005

Change in gene may be underlying molecular defect in some colorectal cancers

Inactivation of a DNA repair gene may be an early step in the development of sporadic colorectal tumors, and detection of the molecular basis for this inactivation may ultimately be useful in risk assessment for colorectal cancer, according to a new study in the September 21 issue of the Journal of the National Cancer Institute.

20 Sep 2005

Gaps in the intestinal barrier could be a cause of inflammatory diseases of the gut such as Crohn's Disease

Their research, led by Professor Alastair Watson in the University's Faculty of Medicine, could have important implications for the treatment of patients with diseases like Crohn's - an inflammatory bowel disorder that causes severe ulceration in the intestine, leading to pain, bleeding and diarrhoea.

20 Sep 2005

Colon News and Research

Gene fusion appears to cause prostate cancer

Lack of gene expression associated with ovarian cancer

Yeast cells help show how GSAO (glutathionarsenoxide) angiogenesis inhibitor drug works

Cosmopolitan Lifestyle could allay cancer threat

Computer-assisted instruction offers the potential to overcome knowledge barriers and improve screening rates

CT colonography best choice for regular screening for cancer

Long-term use of NSAIDs cuts the risk for oral cancer in smokers by half but increases risk of cardiovascular problems

Gene variation may play fundamental role in the development and spread of cancer in the body

Gut antibody could prove to be a promising drug target for Crohn's disease

Cancer incidence among women has increased slightly

Americans' risk of dying from cancer continues to decline

Common cancer susceptibility gene appears to be frequently acquired in metastatic lesions from colorectal cancer

Researchers identify gene defect in mice that causes cyclical hair loss and skin cancer

Behavior-based means of cutting the risks of tobacco

Pursuit of potential drugs and small molecules that target the IGF-1 receptor

Researchers at Johns Hopkins have identified three new genetic mutations in brain tumors

Change in gene may be underlying molecular defect in some colorectal cancers

Next generation of effective viral-based therapies for cancer

Change in gene may be underlying molecular defect in some colorectal cancers

Gaps in the intestinal barrier could be a cause of inflammatory diseases of the gut such as Crohn's Disease

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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