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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Researchers investigate persistence of reproductive cells despite damage from jumping genes

Believe it or not, your genes are 50% parasite, and opportunistic at that. They tend to jump onto sperm and egg cells to replicate in the next generation, a process that can devastate an egg or sperm cell.

1 Sep 2020

Adjuvant chemotherapy can improve overall survival in patients with high-risk, low-grade glioma

A practice-changing study, NRG Oncology clinical trial NRG-RTOG 9802, has demonstrated, for the first time, a survival benefit of adjuvant chemotherapy following radiotherapy over radiotherapy alone in certain subgroups of patients with high-risk, low-grade glioma (WHO classification: LGG, grade II), a type of brain tumor that originates from glial cells.

1 Sep 2020

A nanoscaffolding approach for rapid design of highly immunogenic SARS-CoV-2 vaccines

A research group from Slovenia, Switzerland, and Germany shows how nanoscaffolded assemblies may neutralize interaction between the SARS-CoV-2 spike protein and cell receptor, providing adequate protection in a surrogate infection assay and warranting the advance of such platforms in the pursuit for the effective vaccine.

31 Aug 2020

Previously overlooked insect shows promise as alternative protein source

With global food demands rising at an alarming rate, a study led by IUPUI scientists has found new evidence that a previously overlooked insect shows promise as alternative protein source: the yellow mealworm.

31 Aug 2020

FEFU scientists to design genetically modified models for understanding malignant gliomas

Scientists of Far Eastern Federal University get started studying the formation and survival mechanisms of the brain malignant tumors cells, i.e. glioma, to reveal new ways for diagnosis and therapy for this fatal disease.

31 Aug 2020

T cell epitopes from recovered COVID-19 patients identified for vaccine

A new study by researchers at The Hong Kong University of Science and Technology and published on the preprint server bioRxiv in August 2020 collates the available database of SARS-CoV-2 T cell epitopes gathered from 8 studies of COVID-19 patients who recovered. This could serve as a launchpad to fill in knowledge gaps regarding the immunological aspects of this disease, and drive towards an effective T cell vaccine.

31 Aug 2020

Serum protein shows therapeutic value against severe COVID-19-like features in mouse model

A new study published on the preprint server bioRxiv* in August 2020 reports the disease-mitigating effects of a serum protein called serum amyloid P (SAP) in mice exposed to a peptide that mimics the clinical signs of severe COVID-19 in humans.

30 Aug 2020

Knowledge about past warming events can help create and preserve ecosystems

Approximately 40 per cent of terrestrial ecosystems are projected to have experienced shifts in temperature during the past 21,000 years that are similar in pace and magnitude to regional-scale future forecasts.

29 Aug 2020

Host tissue T cells play a previously unappreciated role in acute graft-versus-host disease

Allogenic hematopoietic stem cell transplantation (HSCT) is a procedure that infuses a donor's healthy blood-forming stem cells into a recipient as part of a potentially curative therapy for cancer.

28 Aug 2020

'Jumping' DNA influences the differentiation, physiological functioning of neurons

The human genome contains over 4.5 million sequences of DNA called "transposable elements", these virus-like entities that "jump" around and help regulate gene expression.

28 Aug 2020

DNA structure is determined by spatial rules based on specific protein sequences and their order

DNA three-dimensional structure is determined by a series of spatial rules based on particular protein sequences and their order.

28 Aug 2020

Researchers identify RNA molecule that aids in lung cancer immune evasion

Researchers in Spain have identified a non-coding RNA molecule that helps lung cancer cells proliferate and avoid being killed by the body's immune cells.

27 Aug 2020

Researchers discover genetic link between cattle temperament and autism in humans

A strong association between the genes influencing cattle temperament and autism in humans has been discovered by University of Queensland researchers.

27 Aug 2020

New sequencing approach can detect rare mutation in large number of cells

A sequencing approach can home in on a rare mutation within a large number of cells, revealing implications for CRISPR genome editing and early cancer detection.

27 Aug 2020

A powerful tool for separation and sizing of virus mixtures

Postnova Analytics has published an applications report that presents data from a collaboration with the Analytical Development group at Biogen Inc. on separation of a virus mixture using Asymmetrical Flow Field-Flow Fractionation and measurement of their radius of gyration.

From Postnova Analytics 27 Aug 2020

UKRI funding could initiate clinical trial for Cambridge-developed DNA vaccine against SARS-CoV-2

A Cambridge-developed DNA vaccine candidate against SARS-CoV-2 could begin clinical trials in the UK in late autumn or early next year, thanks to a £1.9 million award from the UK government.

27 Aug 2020

Largely ignored 'housekeeping' gene plays a role in seizures

Within cells, molecules known as transfer RNAs, or "tRNAs," play an important but unglamorous workhorse role in keeping the genetic translation process moving along from codes of DNA to functional proteins.

26 Aug 2020

Exosomes: The cancer cell communication mechanism

Professor Deborah Goberdhan speaks to News-Medical about her team's latest research into cancer cells, and the mechanisms they use to communicate.

26 Aug 2020

Synthetic gene fragments from SARS-CoV-2 can help produce accurate diagnostic tests

Researchers at the National Institute of Standards and Technology (NIST) have produced synthetic gene fragments from SARS-CoV-2, the virus that causes COVID-19. This material, which is non-infectious and safe to handle, can help manufacturers produce more accurate and reliable diagnostic tests for the disease.

26 Aug 2020

Researchers discover new genes that influence cancer treatment success

One of the great mysteries of cancer research is why certain patients respond better to radiation therapy than others. Researchers at the University of Bern have now discovered which genes play an important role in this. This results in new findings for cancer treatment.

25 Aug 2020

DNA News and Research

Further Reading

Researchers investigate persistence of reproductive cells despite damage from jumping genes

Adjuvant chemotherapy can improve overall survival in patients with high-risk, low-grade glioma

A nanoscaffolding approach for rapid design of highly immunogenic SARS-CoV-2 vaccines

Previously overlooked insect shows promise as alternative protein source

FEFU scientists to design genetically modified models for understanding malignant gliomas

T cell epitopes from recovered COVID-19 patients identified for vaccine

Serum protein shows therapeutic value against severe COVID-19-like features in mouse model

Knowledge about past warming events can help create and preserve ecosystems

Host tissue T cells play a previously unappreciated role in acute graft-versus-host disease

'Jumping' DNA influences the differentiation, physiological functioning of neurons

DNA structure is determined by spatial rules based on specific protein sequences and their order

Researchers identify RNA molecule that aids in lung cancer immune evasion

Researchers discover genetic link between cattle temperament and autism in humans

New sequencing approach can detect rare mutation in large number of cells

A powerful tool for separation and sizing of virus mixtures

UKRI funding could initiate clinical trial for Cambridge-developed DNA vaccine against SARS-CoV-2

Largely ignored 'housekeeping' gene plays a role in seizures

Exosomes: The cancer cell communication mechanism

Synthetic gene fragments from SARS-CoV-2 can help produce accurate diagnostic tests

Researchers discover new genes that influence cancer treatment success

eBook: A guide to RNA sequencing eBook

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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