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Study shows how melanoma cells evade detection and destruction by immune cells

A dysfunctional immune system significantly contributes to the development of cancer. Several therapeutic strategies to activate the immune system to target cancer cells have been approved to treat different types of cancer, including melanoma.

9 Apr 2021

Real-time imaging shines light on the coordination of neural stem cell activation

In all adult vertebrates, neural stem cells can be recruited to produce new neurons in the brain. However, little is known about these so-called "activation" processes.

8 Apr 2021

Study reveals new mutations that make cancer resistant to KRAS-targeted therapies

A gene called KRAS is one of the most commonly mutated genes in all human cancers, and targeted drugs that inhibit the protein expressed by mutated KRAS have shown promising results in clinical trials, with potential approvals by the U.S. Food and Drug Administration anticipated later this year.

7 Apr 2021

Treatment resistance in triple-negative breast cancers linked to softer tissue environment

Researchers at the University of California, San Francisco, have discovered that aggressive, triple-negative breast cancers (TNBCs) can evade treatment by reorganizing and softening the collagen matrix that surrounds the cancer cells.

3 Apr 2021

Study reveals how exercise during pregnancy confers metabolic health benefits in offspring

A mechanism has been identified that explains how physical exercise in pregnancy confers metabolic health benefits in offspring.

30 Mar 2021

Alzheimer’s symptoms linked to COVID-induced brain injury

New research shows further evidence between COVID-19 infection and the development of long-term neurological symptoms. The findings found COVID-induced neuroinflammation and microvascular injury contributed to dementia-like symptoms. However, they also found evidence indicating a low possibility of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) directly invading the brain.

24 Mar 2021

Virginia Tech neuroscientist uses NIH grant to understand astrocytic processes in the healthy brain

Of all the worlds still to be explored, among the most mysterious may be closest to home. Indeed, it may be right between your ears.

22 Mar 2021

Amino acids signaling controls whole-body glucose homeostasis, study shows

Amino acids are a major nutrient type for humans and are used as building blocks and a source of energy for cells.

16 Mar 2021

Cannabis compound inhibits SARS-CoV-2 replication in human lung cells

Researchers in the United States have conducted a study showing that a cannabis plant compound inhibited infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in human lung cells.

14 Mar 2021

New study sheds light on cancer metastasis

Breast cancer is harmful enough on its own, but when cancer cells start to metastasize -- or spread into the body from their original location -- the disease becomes even more fatal and difficult to treat.

12 Mar 2021

Newly discovered cellular stress enzyme may be a target for neurodegenerative disease treatments

An enzyme called MARK2 has been identified as a key stress-response switch in cells in a study by researchers at Johns Hopkins Bloomberg School of Public Health.

11 Mar 2021

Lithium chloride can alleviate radiation-induced oral mucositis and taste dysfunction

Oral mucositis and taste dysfunction (dysgeusia) occurs in nearly all patients receiving head and neck radiotherapy and tremendously affects the quality of life and treatment outcome.

11 Mar 2021

Princeton researchers discover previously unknown organelle that plays role in bone metastasis

Some of Princeton's leading cancer researchers were startled to discover that what they thought was a straightforward investigation into how cancer spreads through the body -- metastasis -- turned up evidence of liquid-liquid phase separations: the new field of biology research that investigates how liquid blobs of living materials merge into each other, similar to the movements seen in a lava lamp or in liquid mercury.

9 Mar 2021

Signaling Pathway News and Research

Study shows how melanoma cells evade detection and destruction by immune cells

Real-time imaging shines light on the coordination of neural stem cell activation

Study reveals new mutations that make cancer resistant to KRAS-targeted therapies

Treatment resistance in triple-negative breast cancers linked to softer tissue environment

Study reveals how exercise during pregnancy confers metabolic health benefits in offspring

Alzheimer’s symptoms linked to COVID-induced brain injury

Virginia Tech neuroscientist uses NIH grant to understand astrocytic processes in the healthy brain

Amino acids signaling controls whole-body glucose homeostasis, study shows

Cannabis compound inhibits SARS-CoV-2 replication in human lung cells

New study sheds light on cancer metastasis

Newly discovered cellular stress enzyme may be a target for neurodegenerative disease treatments

Lithium chloride can alleviate radiation-induced oral mucositis and taste dysfunction

Princeton researchers discover previously unknown organelle that plays role in bone metastasis

Impairments in immune response contribute to severe COVID-19

SARS-CoV-2 escapes host immune responses by modulating dendritic cell maturation

Cell surface marker CD47 may allow early diagnosis of severe COVID-19

Study demonstrates the novel agonistic effect of curcumin on lipid transcription

Proteins play crucial role in muscle growth

High expression of ACE2 receptors in developing ovaries increases SARS-CoV-2 risk

Hormone known to prevent weight gain can help maintain healthy muscles in mice

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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