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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

New test can pinpoint which people with gonorrhea can be cured with ciprofloxacin

A test designed by UCLA researchers can pinpoint which people with gonorrhea will respond successfully to the inexpensive oral antibiotic ciprofloxacin, which had previously been sidelined over concerns the bacterium that causes the infection was becoming resistant to it.

7 Aug 2020

Researchers develop a deep learning-based algorithm for predicting sites of DNA methylation

A team of researchers from New Jersey Institute of Technology and Children's Hospital of Philadelphia have developed an algorithm through machine learning that helps predict sites of DNA methylation - a process that can change the activity of DNA without changing its overall structure - and could identify disease-causing mechanisms that would otherwise be missed by conventional screening methods.

6 Aug 2020

A new method to diagnose brain tumors without any incisions

Brain tumors are typically diagnosed using MRI imaging, as taking a sample for a tissue biopsy is risky and may not be possible due to tumor location or a patient's poor health conditions.

6 Aug 2020

31st International Symposium on Human Identification is going virtual in 2020

Forensic DNA experts from around the world will gather virtually in 2020 for the 31st International Symposium on Human Identification.

6 Aug 2020

Researchers shed new light on epigenetic changes associated with ADNP syndrome

A study led by the Seaver Autism Center for Research and Treatment at Mount Sinai found that two different blood epigenetic signatures associated with ADNP syndrome (also known as Helsmoortel-Van Der Aa syndrome) have only a modest correlation with clinical manifestations of the syndrome. The study results were published online August 5 in the American Journal of Human Genetics.

6 Aug 2020

Discovery of enzyme could provide new route for treating Huntington's disease

Scientists at EPFL's Brain Mind Institute have identified an enzyme that can play a central role in developing a new route of treatment for Huntington's Disease.

5 Aug 2020

Study provides new insights into how ovarian cancer grows and evolves

In a paper published in the journal Cancer Research, professor Levi Waldron, post-doctoral fellow Ludwig Geistlinger, and colleagues at the Institute for Implementation Science in Population Health at the CUNY Graduate School of Public Health and Health Policy) provide new insights into how ovarian cancer grows and evolves within a person.

5 Aug 2020

New research project receives federal funding to expand treatment options for sickle cell patients

A new research project that could impact and expand the discovery of new treatment options for sickle cell patients has received significant federal funding.

5 Aug 2020

Study: Inhibition of TLK protein stimulates the innate immune system

Tousled-like kinases (TLKs) are a potential therapeutic target for cancer treatment due to their central role in DNA repair and replication.

5 Aug 2020

Launching a rapid test for COVID-19

Professor Zhanfeng Cui from the University of Oxford speaks to News-Medical about his research into COVID-19, and how he developed a rapid COVID-19 test.

5 Aug 2020

Neutrolis announces development of first-in-class therapy to target NETs in COVID-19 patients

Neutrolis, a biotechnology company developing therapeutics that target neutrophils, the most abundant immune cells in the body, today announced the development of NTR-441, a first-in-class DNASE1L3 enzyme analog that has the potential to rapidly and systemically clear neutrophil extracellular traps for severe cases of COVID-19.

5 Aug 2020

Embryos are susceptible to COVID-19 if mothers get sick, indicates study

Genes that are thought to play a role in how the SARS-CoV-2 virus infects our cells have been found to be active in embryos as early as during the second week of pregnancy, say scientists at the University of Cambridge and the California Institute of Technology (Caltech).

5 Aug 2020

Study shows link between selenium-deficient diet and paracetamol toxicity

A lack of the mineral selenium in the diet puts people at risk of paracetamol overdose, even when the painkiller is taken at levels claimed to be safe on the packaging, according to collaborative research emerging from the University of Bath and Southwest University in China.

5 Aug 2020

Study shows how regulatory mechanisms contribute to formation of tissues in mouse embryo

A research team at the Max Planck Institute for Molecular Genetics in Berlin has explored the role of factors in embryonic development that do not alter the sequence of DNA, but only epigenetically modify its "packaging"

5 Aug 2020

Genetic variation influencing chromatin states associated with neuropsychiatric disorders

A new study led by NorthShore University HealthSystem and the University of Chicago took a novel approach to identifying SNPs influencing the risk of neuropsychiatric disorders like schizophrenia, bipolar and major depressive disorder, the institutions announced today.

4 Aug 2020

Researchers identify two dozen pesticides linked with mammary gland tumors

In an analysis of how regulators review pesticides for their potential to cause cancer, researchers at Silent Spring Institute identified more than two dozen registered pesticides that were linked with mammary gland tumors in animal studies.

4 Aug 2020

Study identifies impact of gene mutations on severity of myelodysplastic syndrome

The Myelodysplastic Syndromes Group of Josep Carreras Leukaemia Research Institute, led by Dr. Francesc Solé, has participated in the first international study that confirms that having two mutated copies of the TP53 gene, as opposed to a single mutated copy, is associated with a worse prognosis in patients diagnosed with myelodysplastic syndrome (MDS).

4 Aug 2020

CNIO and HKUST researchers identify how some gliomas acquire chemoresistance

A team led by Massimo Squatrito, Head of the Seve Ballesteros Foundation Brain Tumour Group at the Spanish National Cancer Research Centre, have made important findings of how some gliomas can acquire chemoresistance.

4 Aug 2020

Novel mutation identified in SARS-CoV-2 spike protein from Sweden

Researchers from Sweden and Brazil have identified a novel mutation in a strain of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) obtained from a patient in Stockholm, Sweden, in late April.

4 Aug 2020

Machine learning may offer a better way to identify antibiotic-resistant pathogens

Biomedical engineers at Duke University have shown that different strains of the same bacterial pathogen can be distinguished by a machine learning analysis of their growth dynamics alone, which can then also accurately predict other traits such as resistance to antibiotics.

4 Aug 2020

DNA News and Research

Further Reading

New test can pinpoint which people with gonorrhea can be cured with ciprofloxacin

Researchers develop a deep learning-based algorithm for predicting sites of DNA methylation

A new method to diagnose brain tumors without any incisions

31st International Symposium on Human Identification is going virtual in 2020

Researchers shed new light on epigenetic changes associated with ADNP syndrome

Discovery of enzyme could provide new route for treating Huntington's disease

Study provides new insights into how ovarian cancer grows and evolves

New research project receives federal funding to expand treatment options for sickle cell patients

Study: Inhibition of TLK protein stimulates the innate immune system

Launching a rapid test for COVID-19

Neutrolis announces development of first-in-class therapy to target NETs in COVID-19 patients

Embryos are susceptible to COVID-19 if mothers get sick, indicates study

Study shows link between selenium-deficient diet and paracetamol toxicity

Study shows how regulatory mechanisms contribute to formation of tissues in mouse embryo

Genetic variation influencing chromatin states associated with neuropsychiatric disorders

Researchers identify two dozen pesticides linked with mammary gland tumors

Study identifies impact of gene mutations on severity of myelodysplastic syndrome

CNIO and HKUST researchers identify how some gliomas acquire chemoresistance

Novel mutation identified in SARS-CoV-2 spike protein from Sweden

Machine learning may offer a better way to identify antibiotic-resistant pathogens

eBook: A guide to RNA sequencing eBook

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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