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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Researchers are developing comprehensive catalog of functional elements of human and mouse genomes

Scientists around the world have access to a rich trove of information through the Encyclopedia of DNA Elements (ENCODE)--annotated versions of the human and mouse genomes that are vital for interpreting their genetic codes.

30 Jul 2020

Antimalarial drug shows in vitro activity against SARS-CoV-2 and flu viruses

Now, a new study published in the preprint server bioRxiv in July 2020 reports on the antiviral activity of two drugs found in an antimalarial drug currently in phase II trials in South Korea, called Pyramax.

30 Jul 2020

UC San Diego researchers part of special package of human genome studies

Researchers at University of California San Diego School of Medicine are among the contributors to a package of 10 studies, published July 29, 2020 in the journal Nature, describing the latest results from the ongoing Encyclopedia of DNA Elements (ENCODE) project, a worldwide effort led by the National Institutes of Health to understand how the human genome functions.

29 Jul 2020

Study finds fungal isolates with high levels of virulence in different hospitals

A group of researchers from Brazil, Denmark, Italy and Spain analyzed 884 samples of fungi of the genus Candida collected from 16 hospitals and found a significant number of clusters in more than one hospital.

29 Jul 2020

New maps of chemical marks on DNA could help illuminate the causes of developmental disorders

In research that aims to illuminate the causes of human developmental disorders, Salk scientists have generated 168 new maps of chemical marks on strands of DNA--called methylation--in developing mice.

29 Jul 2020

Combination of certain drugs can do more harm than good, shows study

A team of researchers at the Norwegian University of Science and Technology (NTNU) investigating how a certain type of drugs can kill cells has discovered that these drugs can do more harm than good when used in combination with other cancer treatments.

29 Jul 2020

Researchers launch randomized, placebo-controlled clinical trial of pulmozyme in COVID-19 patients

Researchers at Boston Children's Hospital and Brigham and Women's Hospital have launched a randomized, placebo-controlled clinical trial of dornase alfa (Pulmozyme) in patients with severe COVID-19 pneumonia and respiratory failure requiring mechanical ventilation.

29 Jul 2020

'Synthetic lethality' could be exploited for cancer therapy

A Ludwig Cancer Research study has identified a new instance in which the simultaneous mutation of two nonessential genes--neither of which is on its own vital to cell survival--can cause cancer cell death.

28 Jul 2020

Human genome may explain the neonatal origins of chronic immune and inflammatory diseases

A study published in the journal Nature Communications has pinpointed a number of areas of the human genome that may help explain the neonatal origins of chronic immune and inflammatory diseases of later life, including type 1 diabetes, rheumatoid arthritis and coeliac disease.

28 Jul 2020

Simultaneous mutation of two nonessential genes can cause cancer cell death

A Ludwig Cancer Research study has identified a new instance in which the simultaneous mutation of two nonessential genes-;neither of which is on its own vital to cell survival-;can cause cancer cell death.

28 Jul 2020

Exploiting 'synthetic lethality' to identify cancer targets

With advances in genome sequencing, cancer treatments have increasingly sought to leverage the idea of "synthetic lethality," exploiting cancer-specific genetic defects to identify targets that are uniquely essential to the survival of cancer cells.

28 Jul 2020

AI Therapeutics announces start of Phase II clinical trial of potential COVID-19 treatment

AI Therapeutics announced the start of Phase II clinical trial for the treatment of newly diagnosed COVID-19 patients in collaboration with Yale University.

27 Jul 2020

EBV viral genome alters the host epigenetic landscape to drive stomach cancer

The Epstein-Barr virus (EBV), one of the most common human viruses, is associated with about 8-10 per cent of stomach -- or gastric -- cancers, the third leading cause of cancer death globally.

27 Jul 2020

Cancers caused by bacterial toxin might be preventable

Studying DNA mutations in cancers can help clarify how cancers develop and what makes cancer cells different from normal, healthy cells.

27 Jul 2020

National clinical trial to test potential vaccine against SARS-CoV-2

UC San Diego Health and the Altman Clinical and Translational Research Institute, part of UC San Diego School of Medicine, will be sites for an accelerated national clinical trial to assess the efficacy and immunogenicity of a vaccine intended to protect against SARS-CoV-2, the novel coronavirus that causes COVID-19.

25 Jul 2020

Researchers identify TLR7 gene that predisposes elderly patients to severe COVID-19

Current observations suggest that the coronavirus SARS-CoV-2 causes severe symptoms mainly in elderly patients with chronic disease.

25 Jul 2020

Bacteriophages may play a key role in treating prosthetic joint infections

Bacteriophages, or phages, may play a significant role in treating complex bacterial infections in prosthetic joints, according to new Mayo Clinic research.

24 Jul 2020

UCC Innovation launches new spinout company SeqBiome

UCC Innovation today announced the launch of SeqBiome a spinout from APC Microbiome Ireland, SFI Research Centre, University College Cork and Teagasc (the Irish Agriculture and Food Development Authority).

24 Jul 2020

Neurotransmitter-derived lipidoids help carry drugs across the blood-brain barrier in mice

Biomedical engineers at the Tufts University School of Engineering have developed tiny lipid-based nanoparticles that incorporate neurotranmitters to help carry drugs, large molecules, and even gene editing proteins across the blood-brain barrier and into the brain in mice.

24 Jul 2020

Novel CT scan method reduces radiation exposure

A new CT (computed tomography) scan method can reduce radiation dose by splitting a full C-ray beam into thin and small beamlets.

24 Jul 2020

DNA News and Research

Further Reading

Researchers are developing comprehensive catalog of functional elements of human and mouse genomes

Antimalarial drug shows in vitro activity against SARS-CoV-2 and flu viruses

UC San Diego researchers part of special package of human genome studies

Study finds fungal isolates with high levels of virulence in different hospitals

New maps of chemical marks on DNA could help illuminate the causes of developmental disorders

Combination of certain drugs can do more harm than good, shows study

Researchers launch randomized, placebo-controlled clinical trial of pulmozyme in COVID-19 patients

'Synthetic lethality' could be exploited for cancer therapy

Human genome may explain the neonatal origins of chronic immune and inflammatory diseases

Simultaneous mutation of two nonessential genes can cause cancer cell death

Exploiting 'synthetic lethality' to identify cancer targets

AI Therapeutics announces start of Phase II clinical trial of potential COVID-19 treatment

EBV viral genome alters the host epigenetic landscape to drive stomach cancer

Cancers caused by bacterial toxin might be preventable

National clinical trial to test potential vaccine against SARS-CoV-2

Researchers identify TLR7 gene that predisposes elderly patients to severe COVID-19

Bacteriophages may play a key role in treating prosthetic joint infections

UCC Innovation launches new spinout company SeqBiome

Neurotransmitter-derived lipidoids help carry drugs across the blood-brain barrier in mice

Novel CT scan method reduces radiation exposure

eBook: A guide to RNA sequencing eBook

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Automating research - solutions and best practices

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