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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Researchers identify specific target sites for DNA methylases

DNA methylation performs an essential function in mammalian ontogeny. It is also known that abnormalities in this process cause the development of cancers such as leukemia.

22 Jul 2020

Researchers investigate the genetic and molecular basis of PD-L2 regulation

In immune-related disorders, therapy often involves identifying the molecules responsible for immune dysregulation and targeting them using drugs.

22 Jul 2020

Cancer diagnostic capacity should be ramped up to avoid unnecessary deaths, say researchers

Delays to cancer referral through reduced use of the urgent GP referral pathway during the coronavirus pandemic could result in more than a thousand additional deaths in England, a new study reports.

22 Jul 2020

Researchers demonstrate the production of viral parts within artificial cells

Scientists searching for better diagnostic tests, drugs or vaccines against a virus must all begin by deciphering the structure of that virus.

21 Jul 2020

Silver-plated gold nanostars could be used to identify early biomarkers of cancer

Biomedical engineers at Duke University have engineered a method for simultaneously detecting the presence of multiple specific microRNAs in RNA extracted from tissue samples without the need for labeling or target amplification.

21 Jul 2020

Research suggests a possible new approach to treating neurodegenerative diseases

Researchers at Vanderbilt University Medical Center have shown for the first time that when one optic nerve in the eye is damaged, as in glaucoma, the opposite optic nerve comes to the rescue by sharing its metabolic energy.

21 Jul 2020

Early detection of cancer four years before conventional diagnosis using non-invasive blood test

An international team of researchers has developed a non-invasive blood test that can detect whether an individual has one of five common types of cancers, four years before the condition can be diagnosed with current methods. The test detects stomach, esophageal, colorectal, lung and liver cancer.

21 Jul 2020

Chronic inflammation associated with IBD disrupts tissue structure of the colon, study finds

In a new study, researchers have compared diseased colon with healthy tissue to better understand how inflammatory bowel disease (IBD) is linked to an increased risk of colorectal cancers, at a molecular level.

21 Jul 2020

NIH project homes in on COVID racial disparities

While the disproportionate impact of COVID-19 on Black and Hispanic Americans is no secret, federal officials have launched studies of the disparity that they hope will better prepare the country for the next great epidemic.

21 Jul 2020

Promega Maxwell Extraction System added to CDC COVID-19 diagnostic protocol

Promega Corporation’s Maxwell RSC 48 Instrument and Maxwell RSC Viral Total Nucleic Acid Purification Kit are now in the Centers for Disease Control and Prevention’s COVID-19 diagnostic protocol for emergency use.

From Promega Corporation 21 Jul 2020

Gum disease and esophageal and stomach cancer risk

American researchers have published their new findings on gum disease in a research letter in the latest issue of the journal Gut titled, "Periodontal disease, tooth loss, and risk of oesophageal and gastric adenocarcinoma: a prospective study."

20 Jul 2020

Researchers visualize DNA G-quadruplex formation in live cells for the first time

The formation of four-stranded DNA has been tracked in living human cells, allowing scientists to see how it works, and its possible role in cancer.

20 Jul 2020

Reproductive outcomes predicted by label-free imaging technique

Researchers at the Beckman Institute for Advanced Science and Technology and the Department of Animal Sciences have collaborated to develop a new technique that can be used to determine the fertility of sperm samples.

20 Jul 2020

Researchers identify underlying mechanism for metabolic memory and diabetic complications

For people with diabetes, vascular complications like kidney disease and atherosclerosis, which can lead to poor health and even death, are seen at increased rates.

20 Jul 2020

COVID-19 vaccine displays protective traits in nonhuman primates

A replicating RNA vaccine, formulated with a lipid-based nanoparticle emulsion that goes by the acronym LION, produces antibodies against the COVID-19 coronavirus in mice and primates with a single immunization. These antibodies potently neutralize the virus.

20 Jul 2020

'Smart nanosheets' can help quickly isolate new types of proteins from mixtures

An interdisciplinary team from Frankfurt and Jena has developed a kind of bait with which to fish protein complexes out of mixtures.

20 Jul 2020

Prostate tumors reactivate dormant molecular program during metastatic progression

When prostate cancer progresses to a more-dangerous metastatic state, it does so by resurrecting dormant molecular mechanisms that had guided the fetal development of the prostate gland but had been subsequently switched off, say scientists from Dana-Farber Cancer Institute.

20 Jul 2020

Mutant zebrafish opens a window into evolutionary history of human spine

A chance mutation that led to spinal defects in a zebrafish has opened a little window into our own fishy past.

20 Jul 2020

China's Ad5 vectored COVID-19 vaccine safe and induces immune response

A phase 2 trial of an Ad5 vectored COVID-19 vaccine candidate, conducted in China, has found that the vaccine is safe and induces an immune response, according to new research published in The Lancet.

20 Jul 2020

Study: Luminescent substance enables accurate observation of different areas of the organism

A luminescent fluid made up of nanoparticles that allows more accurate observation of different areas of the organism has been developed by a research team from the Colloidal Materials group of the Institute of Materials Science of Seville (a CSIC-University of Seville joint centre) in collaboration with the Institute of Materials Science of Aragon, the Andalusian Centre of Medicine and Biotechnology (BIONAND) and the Spanish National Accelerator Centre (CNA).

20 Jul 2020

DNA News and Research

Further Reading

Researchers identify specific target sites for DNA methylases

Researchers investigate the genetic and molecular basis of PD-L2 regulation

Cancer diagnostic capacity should be ramped up to avoid unnecessary deaths, say researchers

Researchers demonstrate the production of viral parts within artificial cells

Silver-plated gold nanostars could be used to identify early biomarkers of cancer

Research suggests a possible new approach to treating neurodegenerative diseases

Early detection of cancer four years before conventional diagnosis using non-invasive blood test

Chronic inflammation associated with IBD disrupts tissue structure of the colon, study finds

NIH project homes in on COVID racial disparities

Promega Maxwell Extraction System added to CDC COVID-19 diagnostic protocol

Gum disease and esophageal and stomach cancer risk

Researchers visualize DNA G-quadruplex formation in live cells for the first time

Reproductive outcomes predicted by label-free imaging technique

Researchers identify underlying mechanism for metabolic memory and diabetic complications

COVID-19 vaccine displays protective traits in nonhuman primates

'Smart nanosheets' can help quickly isolate new types of proteins from mixtures

Prostate tumors reactivate dormant molecular program during metastatic progression

Mutant zebrafish opens a window into evolutionary history of human spine

China's Ad5 vectored COVID-19 vaccine safe and induces immune response

Study: Luminescent substance enables accurate observation of different areas of the organism

eBook: Exploring the Cell Cycle and DNA Damage and Repair eBook

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