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Researchers identify biomarkers for rare, serious complication in children with COVID-19

The study focused on multisystem inflammatory syndrome in children (MIS-C), an inflammatory response involving multiple organs that can occur weeks after infection with SARS-CoV-2, the virus that causes COVID-19.

31 Aug 2021

Investigational vaccine does not provide sufficient protection against HIV infection

An investigational HIV vaccine tested in the "Imbokodo" clinical trial conducted in sub-Saharan Africa posed no safety concerns but did not provide sufficient protection against HIV infection, according to a primary analysis of the study data. The Phase 2b proof-of-concept study, which began in November 2017, enrolled 2,637 women ages 18 to 35 years from five countries.

31 Aug 2021

Researchers develop adult lung organoids that represent all cell types

Since the COVID-19 pandemic reached the United States in early 2020, scientists have struggled to find laboratory models of SARS-CoV-2 infection, the respiratory virus that causes COVID-19. Animal models fell short; attempts to grow adult human lungs have historically failed because not all of the cell types survived.

31 Aug 2021

New, one-stop method developed to avoid de novo genetic disease in embryos

De novo variants (DNVs), genetic mutations that were not previously identifiable in the family history of one of two prospective parents, may cause disease in any children they have.

31 Aug 2021

SARS-CoV-2 animal origin: What we know so far

Scientists at the University of Glasgow Centre for Virus Research in the United Kingdom and the South China Agricultural University in Guangzhou, China, have shed light on the animal origin of SARS-CoV-2, tracing back to the first outbreak of the severe acute respiratory syndrome coronavirus (SARS-CoV), the infectious agent of the severe acute respiratory syndrome (SARS) in China in 2002 to 2003.

31 Aug 2021

Vaccinated individuals with breakthrough SARS-CoV-2 infection have much lower risk of hospitalization

A recent study conducted by a team of US-based scientists has revealed that unvaccinated individuals are 17-times more likely to be hospitalized due to severe coronavirus disease 2019 (COVID-19) compared to those vaccinated against the disease. The study is currently available on the medRxiv* preprint server.

31 Aug 2021

Researchers identify 55 lingering effects of COVID-19

As COVID-19 hospitalizations once again soar in a fourth surge more than 18 months after the pandemic started, some patients continue to experience symptoms long after recovering from COVID, according to a Houston Methodist study recently published in Nature's Scientific Reports.

30 Aug 2021

Discovery of new urinary biomarkers can boost the surveillance of synthetic drug abuse

A team of researchers from the National University of Singapore has come up with a new solution to boost the surveillance of designer drug abuse.

30 Aug 2021

Researchers study the role of low-density granulocytes in COVID-19

Information on granulocytes helps to understand mechanisms associated with covid-19 and other infectious diseases. Such information also promotes the development of better diagnostic methods and therapies.

30 Aug 2021

Can SARS-CoV-2 be transmitted in the food cold chain?

A new study reports that the risk of transmitting SARS-CoV-2 through such fomites is very low.

30 Aug 2021

Neurons in visual cortex of the brain change their responses over time, research reveals

New research from Washington University in St. Louis reveals that neurons in the visual cortex -; the part of the brain that processes visual stimuli -; change their responses to the same stimulus over time.

28 Aug 2021

Researchers test remotely operated implantable drug delivery devices on the ISS

From Novartis to Lamborghini, Alessandro Grattoni and the Houston Methodist Research Institute have partnered with big names to leverage the International Space Station U.S. National Laboratory for space-based research and technology development with important benefits back on Earth.

28 Aug 2021

Jaw surgery takes a $27,119 bite out of one man’s budget

For years, Ely Bair dealt with migraine headaches, jaw pain and high blood pressure, until a dentist recommended surgery to realign his jaw to get to the root of his health problems.

27 Aug 2021

Study examines safety of COVID-19 vaccine in a nationwide mass-vaccination setting

The Clalit Research Institute, in collaboration with researchers from Harvard University, analyzed one of the world's largest integrated health record databases to examine the safety of the Pfizer/BioNTech BNT162B2 vaccine against COVID-19.

27 Aug 2021

Pediatric cancer patients fare worse with COVID-19 than children without cancer

Research from a large international effort shows that 20% of children with cancer who are infected with SARS-CoV-2 develop severe infections.

27 Aug 2021

COVID-19 pandemic illuminates the importance of airborne transmission of respiratory viruses

SARS-CoV-2, the virus behind today's global coronavirus pandemic, spreads primarily by inhalation of virus-laden aerosols at both short and long ranges -;and a comprehensive new assessment of respiratory viruses finds that many others probably do as well.

27 Aug 2021

Researchers convert human stem cells into beta cells using small molecules

The human body can be genetically inclined to attack its own cells, destroying the beta cells in the pancreas that make insulin, which helps convert sugar into energy.

27 Aug 2021

New machine learning techniques help resolve structural biology challenges

Determining the 3D shapes of biological molecules is one of the hardest problems in modern biology and medical discovery. Companies and research institutions often spend millions of dollars to determine a molecular structure – and even such massive efforts are frequently unsuccessful.

27 Aug 2021

New MOGONET outperforms existing supervised multi-omics integrative analysis approaches

Genomics, proteomics, metabolomics, transcriptomics -- rapid advances in high-throughput biomedical technologies has enabled the collection of data with unprecedented detail from the growing number of omics.

27 Aug 2021

Cytokine APRIL plays a protective role against formation of atherosclerotic plaques

Heart attacks and strokes are the main causes of death and loss of productive years globally. These clinical complications are caused by atherosclerosis, which is a chronic disease that leads to the accumulation of LDL cholesterol and immune cells in the inner layer of arteries and thereby resulting in the build-up of atherosclerotic plaques.

26 Aug 2021

Laboratory News and Research

Researchers identify biomarkers for rare, serious complication in children with COVID-19

Investigational vaccine does not provide sufficient protection against HIV infection

Researchers develop adult lung organoids that represent all cell types

New, one-stop method developed to avoid de novo genetic disease in embryos

SARS-CoV-2 animal origin: What we know so far

Vaccinated individuals with breakthrough SARS-CoV-2 infection have much lower risk of hospitalization

Researchers identify 55 lingering effects of COVID-19

Discovery of new urinary biomarkers can boost the surveillance of synthetic drug abuse

Researchers study the role of low-density granulocytes in COVID-19

Can SARS-CoV-2 be transmitted in the food cold chain?

Neurons in visual cortex of the brain change their responses over time, research reveals

Researchers test remotely operated implantable drug delivery devices on the ISS

Jaw surgery takes a $27,119 bite out of one man’s budget

Study examines safety of COVID-19 vaccine in a nationwide mass-vaccination setting

Pediatric cancer patients fare worse with COVID-19 than children without cancer

COVID-19 pandemic illuminates the importance of airborne transmission of respiratory viruses

Researchers convert human stem cells into beta cells using small molecules

New machine learning techniques help resolve structural biology challenges

New MOGONET outperforms existing supervised multi-omics integrative analysis approaches

Cytokine APRIL plays a protective role against formation of atherosclerotic plaques

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