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New blood test could save thousands of lives by predicting sepsis before symptoms appear

Clinicians at Portsmouth's Queen Alexandra Hospital are leading medical trials of a blood test that could help to save thousands of UK lives a year by predicting sepsis days before patients show any symptoms.

26 Aug 2021

Study unravels widespread tumor suppression mechanism that halts cancer metastasis

According to a study by The Wistar Institute, the tumor suppressor Parkin, whose levels are reduced in different cancer types, causes acute metabolic and oxidative stress, suppresses mitochondrial trafficking, and blocks tumor cell movement, reducing primary and metastatic tumor growth.

26 Aug 2021

An existing drug may function as targeted therapy for ALL in children

A new study from Linköping University has shown that the tumour-inhibiting gene TET2 is silenced in a large fraction of cases of acute lymphoblastic leukemia (ALL) in children.

25 Aug 2021

The woman behind the development of mRNA-based vaccines against coronavirus

With her research, biochemist Katalin Karikó laid the foundation for the development of RNA vaccines against the coronavirus. Now she is being honoured for this by the Würzburg Societas Physico-Medica.

25 Aug 2021

Prevalence of suicidal thinking did not increase among veterans during the pandemic

Many public health experts feared the COVID-19 pandemic would cause an increase in suicidal behavior among U.S. military veterans, a group that already has high rates of depression and posttraumatic stress disorder and which experienced a 30% surge in suicides between 2010 and 2018.

25 Aug 2021

Study uncovers epigenetic mechanisms that promote glioma tumor growth

Northwestern Medicine investigators have discovered the epigenetic mechanisms involved in the regulation of multiple oncogenes in glioma cells, mechanisms that promote overall glioma tumor growth and resistance to therapy, according to a study published in the journal Clinical Cancer Research.

25 Aug 2021

Less than 20% of patients with laboratory evidence of kidney disease are referred to nephrologists

Less than 20% of patients with laboratory evidence of kidney disease are referred for specialty care but most patients who are not referred have low predicted two-year risk of kidney failure.

25 Aug 2021

Higher mortality rates and age-related disease patterns in pediatric COVID-19

The current study examines children in pediatric ICU (PICU) care with COVID-19. Read more here.

25 Aug 2021

Persistence of Anti-PF4 levels in VITT patients four months after AstraZeneca COVID-19 vaccine

A study published on medRxiv* preprint server reported the over-time changes in the ability of the serum to activate platelets in vitro.

25 Aug 2021

Unconventional T cell and inflammation levels in COVID-19 during pregnancy

A new study published on the medRxiv* preprint server has focused on investigating SARS-CoV-2 immune responses in pregnant women

25 Aug 2021

Hot spots where covid vaccination lags push experimental antibody treatment

For months, Joelle Ruppert was among the millions of Americans who are covid vaccine holdouts. Her reluctance, she said, was not so much that she opposed the new vaccines but that she never felt "compelled" by the evidence supporting their experimental use.

25 Aug 2021

Research highlights the potential benefits of SARS-CoV-2 S gene mutants as immunogens

Previous research has shown that the spike (S) protein of -CoV-2 binds to a host cell receptor, facilitating viral entry.

25 Aug 2021

Study focuses on understanding how muscle fatigue and changes in gait affect older adults

Older adults on a walk or hike, or just going about their daily routines, seem to experience greater fatigue than their younger counterparts. Such fatigue may ultimately affect their ability to participate in activities that are meaningful to them and help keep them healthy.

25 Aug 2021

Study on SARS-CoV-2 Delta breakthrough infections shows twice the risk as Alpha

A recent study conducted by Portuguese scientists has claimed that mRNA-based coronavirus disease 2019 (COVID-19) vaccines are less effective against the delta variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Moreover, in breakthrough infections by delta variant, vaccines are less effective in reducing viral loads. The study is currently available on the medRxiv* preprint server.

25 Aug 2021

Study finds a new line of drugs to stimulate myelin repair in multiple sclerosis

In the nearly 1 million Americans living with multiple sclerosis, the fatty substance that insulates the nerves of the central nervous system—called myelin—is damaged.

24 Aug 2021

Intestinal microorganisms help regulate anti-tumor immune responses to radiation therapy, study finds

Cedars-Sinai Cancer researchers have discovered that intestinal microorganisms help regulate anti-tumor immune responses to radiation treatments, and that fungi and bacteria have opposing effects on those responses.

24 Aug 2021

Population peak could contribute to less meaningful social interactions and reproduction suppression

A predicted population drop at the end of the century could be explained by stress from meaningless social interactions, according to a review article published in the Endocrine Society's journal, Endocrinology.

24 Aug 2021

First-in-kind kidney cancer drug developed at UTSW receives FDA approval

A first-in-kind kidney cancer drug developed from laboratory and translational studies conducted at UT Southwestern Medical Center received approval from the Food and Drug Administration, providing a new treatment for patients with familial kidney cancer.

24 Aug 2021

Atomic-level imaging of infectious prions reveals new therapeutic targets for untreatable diseases

The highest-ever resolution imaging of an infectious prion provides the first atomic-level data of how these abnormal proteins are assembled to cause fatal neurodegenerative diseases in people and animals-; and how they can be potentially targeted by new therapies.

24 Aug 2021

UCR researchers gauge social responsibility in reducing COVID-19 spread

Uncertainty and anxiety generated by the COVID-19 pandemic motivated social psychologist Evelyn Vázquez at the University of California, Riverside, to collaborate with UCR Healthy Campus on a study to identify safety measures and public health messaging that reduce the spread of the coronavirus within campus communities.

24 Aug 2021

Laboratory News and Research

New blood test could save thousands of lives by predicting sepsis before symptoms appear

Study unravels widespread tumor suppression mechanism that halts cancer metastasis

An existing drug may function as targeted therapy for ALL in children

The woman behind the development of mRNA-based vaccines against coronavirus

Prevalence of suicidal thinking did not increase among veterans during the pandemic

Study uncovers epigenetic mechanisms that promote glioma tumor growth

Less than 20% of patients with laboratory evidence of kidney disease are referred to nephrologists

Higher mortality rates and age-related disease patterns in pediatric COVID-19

Persistence of Anti-PF4 levels in VITT patients four months after AstraZeneca COVID-19 vaccine

Unconventional T cell and inflammation levels in COVID-19 during pregnancy

Hot spots where covid vaccination lags push experimental antibody treatment

Research highlights the potential benefits of SARS-CoV-2 S gene mutants as immunogens

Study focuses on understanding how muscle fatigue and changes in gait affect older adults

Study on SARS-CoV-2 Delta breakthrough infections shows twice the risk as Alpha

Study finds a new line of drugs to stimulate myelin repair in multiple sclerosis

Intestinal microorganisms help regulate anti-tumor immune responses to radiation therapy, study finds

Population peak could contribute to less meaningful social interactions and reproduction suppression

First-in-kind kidney cancer drug developed at UTSW receives FDA approval

Atomic-level imaging of infectious prions reveals new therapeutic targets for untreatable diseases

UCR researchers gauge social responsibility in reducing COVID-19 spread

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