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Viralytics announces completion of $28 million placement

Viralytics Limited announces that it has completed a placement of 46,118,270 shares to international and domestic sophisticated or professional investors at an issue price of $0.615 per share to raise $28,362,736.

14 Dec 2015

Cancer rates rise in many low-and middle-income countries

Improved screening and detection efforts, combined with decreases in risk factors like smoking, have reduced the incidence and mortality rates from several common types of cancer in many high-income countries. However, many low-and middle-income countries have seen cancer rates rise, partially due to increases in risk factors that are typical of Western countries.

14 Dec 2015

Innovative Phase II trial evaluates effectiveness of diabetes medication for lymphoma

Cancer, it could be said, grows like a weed: rapidly, invasively, and with devastating impact on the place it infests. Also like a weed, cancer can't grow on its own — it needs nourishment, which it drains from the human body, just as weeds take nutrients in the soil away from other plants.

13 Dec 2015

Researchers use endocytic pathways to sort out NSCLC lines into two distinct clusters

In the Age of Personalized Medicine, we've learned that one size doesn't fit all, least of all in cancer. Cancer is a disease of your cells, and sorting out your cancer from all others is a daunting challenge but one that cancer cell biologists are furiously pursuing. They are examining every aspect of cell function and cell structure, looking for clusters of phenotypes that could label a patient's cancer so precisely that it could be linked to therapies proven effective against just that type.

12 Dec 2015

Alecensa (alectinib) approved for treatment of people with advanced ALK-positive NSCLC

The U.S. Food and Drug Administration today approved Alecensa (alectinib) to treat people with advanced (metastatic) ALK-positive non-small cell lung cancer (NSCLC) whose disease has worsened after, or who could not tolerate treatment with, another therapy called Xalkori (crizotinib).

11 Dec 2015

Post-progression afatinib exposure boosts NSCLC outcomes

Continued exposure to afatinib plus paclitaxel can benefit non-small-cell lung cancer patients who developed resistance to erlotinib or gefitinib and progressed after initially responding to afatinib monotherapy, suggest phase III trial results.

11 Dec 2015

TBK1 protein plays vital role in the process of cell division

Moffitt Cancer Center researchers have found that a protein called TBK1 plays an important role in the process of cell division, especially at a stage called mitosis.

11 Dec 2015

Virologists demonstrate how poxviruses defeat the body's host immune defenses

Smallpox virus, which killed millions of humans through the ages, ranks among the world's most feared bioterrorism agents. Human monkeypox continues to occur sporadically in remote African villages.

11 Dec 2015

Providing novice surgeons with regular feedback can help prevent blood clots among hospitalized patients

A study of general surgery residents at The Johns Hopkins Hospital suggests that in the efforts to prevent dangerous blood clots among hospitalized patients, regular, one-on-one feedback and written report cards work a lot better than the usual group lectures that newly minted surgeons receive as part of their training.

11 Dec 2015

Scientists find effective antiviral mechanisms to inhibit chikungunya virus

Scientists looking at the antiviral mechanisms of two previously identified human monoclonal antibodies have found they potently inhibit chikungunya virus (CHIKV) at multiple stages of infection.

11 Dec 2015

Lilly, Merck announce another immuno-oncology collaboration

Eli Lilly and Company and Merck, known as MSD outside the United States and Canada, today announced another immuno-oncology collaboration that will evaluate abemaciclib (LY2835219), Lilly's cyclin-dependent kinase (CDK) 4 and 6 inhibitor, and Merck's KEYTRUDA (pembrolizumab) in a Phase I study across multiple tumor types.

10 Dec 2015

Boehringer Ingelheim begins SENSCIS study to investigate safety, efficacy of nintedanib in patients with SSc-ILD

Boehringer Ingelheim announced today that the first person has been enrolled in the SENSCIS (Safety and Efficacy ofNintedanib in Systemic SClerosIS) study.

10 Dec 2015

Scientists discover that blocking RANKL protein stops osteosarcoma

Scientists at Princess Margaret Cancer Centre have discovered that blocking the master regulator of bone renewal stops osteosarcoma - the most common primary bone cancer in children and teens, and the malignant disease that was fatal for Canadian icon Terry Fox.

10 Dec 2015

Novel technology can improve quality of life for children with scoliosis

Scoliosis - typically defined as the curvature of the spine— affects around 3 out of every 100 people. While most cases of scoliosis are mild, some children develop spine deformities that continue to get more severe as they grow. An especially severe spinal curve can reduce the amount of space within the chest, making it difficult for the lungs to function properly.

10 Dec 2015

Study reveals pathogenetic role of miR-125a in pulmonary hypertension

Pulmonary hypertension is an umbrella term used for many conditions that all result in elevation of the pulmonary arterial pressure. Of interest, many of these completely different clinical and pathophysiological entities result in a final common pathway of vasoconstriction, micro thrombosis and vascular remodelling.

10 Dec 2015

Racial disparities exist for black and Hispanic patients undergoing major surgeries in U.S. hospitals

Considerable racial disparities exist in surgical outcomes for black and Hispanic patients undergoing major cancer and non-cancer surgeries in U.S. hospitals, even among institutions that have already enrolled in a national surgical quality improvement initiative.

9 Dec 2015

New three-drug delivery system shows promise for treatment of metastatic melanoma

Researchers have developed a new three-drug delivery system for cancer treatment, especially metastatic melanoma, the deadliest form of skin cancer - and shown that the system may have particular value with cancers like this that often spread through the lymphatic system.

9 Dec 2015

Ground breaking technology could revolutionise cancer diagnosis

A University of Warwick computer scientist is working with technology that could revolutionise how some cancers are diagnosed.

9 Dec 2015

X-rays not reliable for diagnosing hip osteoarthritis in majority of cases

In the majority of cases, hip x-rays are not reliable for diagnosing hip osteoarthritis (OA), and can delay the treatment of this debilitating disease.

9 Dec 2015

Gene mutations that cause congenital heart disease also lead to neurodevelopmental delays

Some of the same gene mutations that cause heart defects in children also lead to neurodevelopmental delays, including learning disabilities. A large study of congenital heart disease (CHD) reveals overlapping genetic influences during early childhood development.

9 Dec 2015

Lungs News and Research

Viralytics announces completion of $28 million placement

Cancer rates rise in many low-and middle-income countries

Innovative Phase II trial evaluates effectiveness of diabetes medication for lymphoma

Researchers use endocytic pathways to sort out NSCLC lines into two distinct clusters

Alecensa (alectinib) approved for treatment of people with advanced ALK-positive NSCLC

Post-progression afatinib exposure boosts NSCLC outcomes

TBK1 protein plays vital role in the process of cell division

Virologists demonstrate how poxviruses defeat the body's host immune defenses

Providing novice surgeons with regular feedback can help prevent blood clots among hospitalized patients

Scientists find effective antiviral mechanisms to inhibit chikungunya virus

Lilly, Merck announce another immuno-oncology collaboration

Boehringer Ingelheim begins SENSCIS study to investigate safety, efficacy of nintedanib in patients with SSc-ILD

Scientists discover that blocking RANKL protein stops osteosarcoma

Novel technology can improve quality of life for children with scoliosis

Study reveals pathogenetic role of miR-125a in pulmonary hypertension

Racial disparities exist for black and Hispanic patients undergoing major surgeries in U.S. hospitals

New three-drug delivery system shows promise for treatment of metastatic melanoma

Ground breaking technology could revolutionise cancer diagnosis

X-rays not reliable for diagnosing hip osteoarthritis in majority of cases

Gene mutations that cause congenital heart disease also lead to neurodevelopmental delays

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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