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New vaccine appears to be more effective in reducing 'bad' LDL cholesterol

A new cholesterol-lowering vaccine leads to reductions in 'bad' LDL cholesterol in mice and macaques, according to research published in Vaccine. The authors of the study, from the University of New Mexico and the National Institutes of health in the United States, say the vaccine has the potential to be a more powerful treatment than statins alone.

10 Nov 2015

Isosorbide mononitrate does not increase HFpEF patients' daily activity level

Heart failure patients with preserved ejection fraction (HFpEF) -- where the heart becomes stiff and cannot relax or fill properly -- did not have increased exercise tolerance after taking isosorbide mononitrate, compared to a placebo, according to a study presented today at the American Heart Association's Scientific Sessions 2015.

10 Nov 2015

Sorafenib increases progression-free survival and disease control rate in NSCLC patients

Sorafenib, a tyrosine kinase inhibitor (TKI) targeting the receptors for vascular endothelial growth factor, platelet derived growth factor, and mast/stem cell growth factor, modestly increases progression-free survival (PFS), time to progression, and disease control rate in non-small cell lung cancer (NSCLC) patients who have relapsed or failed two or three previous treatment regimens.

10 Nov 2015

Cancer survivors' journeys chronicled by Bethlehem artist and cancer survivor Susan Schaffer

Chronicling the journeys of cancer survivors, friends and family has been an emotional process, one filled with joy and shared sorrow for Bethlehem artist and cancer survivor Susan H. Schaffer. As part of her Visions of Hope series of acrylic paintings, Susan offers insight into the windows of the soul - her collection captures the eyes of the people willing to share their respective cancer journeys with her.

9 Nov 2015

AACR rapid and dramatic responses in TRK fusion patients

Loxo Oncology, Inc., a biopharmaceutical company innovating the development of highly selective medicines for patients with genetically defined cancers, today announced new results from its Phase 1 open-label, dose-escalation trial of LOXO-101, a selective inhibitor of tropomyosin receptor kinase (TRK) signaling molecules, and the first preclinical data for its RET and FGFR programs. The data are being presented at the 2015 AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics in Boston.

9 Nov 2015

Combatting viral and bacterial lung infections with volatile anesthetics: an interview with Dr Chakravarthy

Inhaled anesthetics are fairly common all over the world for minor and extensive surgical procedures in patients of all age groups. In the olden days when anesthesia was first developed, ether was the first inhaled anesthetic. That has been replaced, with the more recent discoveries of sevoflurane, isoflurane, and desflurane.

9 Nov 2015

CareFusion to display new respiratory solutions at AARC Congress

CareFusion, a BD company, will be displaying new respiratory solutions that are designed to put patients first, whether ventilated or breathing on their own, at the American Association for Respiratory Care Congress being held Nov. 7-10 in Tampa, Fla.

6 Nov 2015

Viralytics enters into clinical trial collaboration agreement with MSD

Viralytics Limited announced today that it has entered into a clinical trial collaboration agreement through subsidiaries of Merck & Co., Inc., Kenilworth, New Jersey, U.S.A. (known as MSD outside the United States and Canada) to evaluate the combination of Viralytics' investigational cancer immunotherapy CAVATAK, with MSD's KEYTRUDA, an anti-PD-1 (programmed death receptor-1) therapy.

6 Nov 2015

Utah chemists devise new way to detect DNA damage

University of Utah chemists devised a new way to detect chemical damage to DNA that sometimes leads to genetic mutations responsible for many diseases, including various cancers and neurological disorders.

6 Nov 2015

Scientists discover small molecule that can block growth of BRCA-deficient cancer cells

Cancer cells with mutations in BRCA1 or BRCA2 genes, which serve a vital role in preserving the integrity of the genetic code, are key targets for cancer therapeutics. Yet, few agents can selectively eliminate cells deficient in BRCA, and none can do so without the risk of inducing drug resistance.

6 Nov 2015

New tool could help identify patients most likely to benefit from chemoprevention

A team of scientists, led by researchers at University of California, San Diego Moores Cancer Center and The University of Texas MD Anderson Cancer Center, report that a genetic biomarker called loss of heterozygosity or LOH is able to predict which patients with premalignant mouth lesions are at highest risk of developing oral cancer.

6 Nov 2015

Specific gut bacteria can improve cancer immunotherapy, show studies

By introducing a particular strain of bacteria into the digestive tracts of mice with melanoma, researchers at the University of Chicago were able to boost the ability of the animal's immune systems to attack tumor cells. T

6 Nov 2015

Man dies after developing tapeworm tumors

A man has died as a result of tapeworm tumors growing inside his body, doctors report.

5 Nov 2015

Accuray announces installation of CyberKnife M6 and TomoTherapy Systems at FALP Cancer Institute in Chile

Accuray Incorporated announced today that the first CyberKnife M6 and TomoTherapy Systems in Chile are now installed at Fundacion Arturo Lopez Perez (FALP) Cancer Institute in Santiago, Chile. FALP is also the first hospital in Latin America to install both Accuray systems.

5 Nov 2015

Stressed Latino parents twice as likely to have children with obesity

Prior research has shown that stress is associated with obesity in adults, and now for the first time, research suggests Latino parents who feel high levels of stress are twice as likely to have children with obesity as well. Researchers led by Carmen Isasi, MD, PhD, from Albert Einstein College of Medicine in New York, examined data from the Study of Latino Youth (SOL Youth), a study funded by the National, Heart, Lung, and Blood Institute of NIH, to determine the relationship between parental stress and child weight status in the Latino population.

5 Nov 2015

Experts to gather at DOHaD congress to address challenges that impact health of children, adolescents

Over 600 experts from around the world will meet to address the many challenges that currently impact the health of mothers, babies in the womb, infants, children and adolescents at the Society for the Developmental Origins of Health and Disease congress, which will be held in Africa for the first time.

5 Nov 2015

Nucala (mepolizumab) approved for treatment of asthma patients

The U.S. Food and Drug Administration today approved Nucala (mepolizumab) for use with other asthma medicines for the maintenance treatment of asthma in patients age 12 years and older. Nucala is approved for patients who have a history of severe asthma attacks (exacerbations) despite receiving their current asthma medicines.

5 Nov 2015

Addressing quality of life needs in prostate cancer: an interview with Professor Louis Denis

Modern patient-directed management is based on optimal, individual medical treatment and holistic personalised patient-centred care. This is certainly true in prostate cancer where most patients are over 60 years of age. They face a negative physical and functional impact from the diagnosis as well as from the treatment with emotional and social challenges.

4 Nov 2015

New network formed to provide area-wide care for lung cancer patients in Northern Germany

The Pius Hospital Oldenburg, the Institute of Haematopathology Hamburg and NEO New Oncology AG announced today the formation of NOWEL, the North-East-West Lung Network.

4 Nov 2015

New clinical trial uses aggressive treatment method for patients with pancreas cancer

Pancreas cancer remains one of the deadliest cancers worldwide. In the United States, it accounts for only three percent of all diagnosed cancers but it causes almost seven percent of all cancer deaths. A pancreas cancer diagnosis often comes after age 50 and after the cancer has spread, making it difficult to remove surgically.

4 Nov 2015

Lungs News and Research

New vaccine appears to be more effective in reducing 'bad' LDL cholesterol

Isosorbide mononitrate does not increase HFpEF patients' daily activity level

Sorafenib increases progression-free survival and disease control rate in NSCLC patients

Cancer survivors' journeys chronicled by Bethlehem artist and cancer survivor Susan Schaffer

AACR rapid and dramatic responses in TRK fusion patients

Combatting viral and bacterial lung infections with volatile anesthetics: an interview with Dr Chakravarthy

CareFusion to display new respiratory solutions at AARC Congress

Viralytics enters into clinical trial collaboration agreement with MSD

Utah chemists devise new way to detect DNA damage

Scientists discover small molecule that can block growth of BRCA-deficient cancer cells

New tool could help identify patients most likely to benefit from chemoprevention

Specific gut bacteria can improve cancer immunotherapy, show studies

Man dies after developing tapeworm tumors

Accuray announces installation of CyberKnife M6 and TomoTherapy Systems at FALP Cancer Institute in Chile

Stressed Latino parents twice as likely to have children with obesity

Experts to gather at DOHaD congress to address challenges that impact health of children, adolescents

Nucala (mepolizumab) approved for treatment of asthma patients

Addressing quality of life needs in prostate cancer: an interview with Professor Louis Denis

New network formed to provide area-wide care for lung cancer patients in Northern Germany

New clinical trial uses aggressive treatment method for patients with pancreas cancer

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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