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Gut-dwelling bacteria can promote the desire to exercise, study shows

Some species of gut-dwelling bacteria activate nerves in the gut to promote the desire to exercise, according to a study in mice that was led by researchers at the Perelman School of Medicine at the University of Pennsylvania.

15 Dec 2022

What is the role of the pediatric gut microbiome in COVID-19?

Recently, scientists have reviewed the available evidence on the gut microbiome in children with COVID-19 and published it in Microorganisms.

15 Dec 2022

Study examines the role of brain-gut microbiome system in discrimination-related health issues

Structural racism has not only psychosocial but also biological consequences. Discrimination has been shown to contribute to mental and physical disorders including obesity, depression, and addiction, but the biological pathways from a social experience to its impacts on the body remain unknown.

13 Dec 2022

Nanomaterial can indirectly affect the immune system via the gut microbiome, study shows

The nanomaterial graphene oxide-;which is used in everything from electronics to sensors for biomolecules-;can indirectly affect the immune system via the gut microbiome, as shown in a new study on zebrafish by researchers at Karolinska Institutet in Sweden.

12 Dec 2022

What are the associations of metabolome, microbiome, and immune perturbations with severe COVID-19?

In a new study, researchers observed that coronavirus disease 2019 (COVID-19) progression and inflammatory responses are associated with changes in the metabolome and microbiome.

8 Dec 2022

Understanding why respiratory infections are more common in the winter

Researchers investigate the role of extracellular vesicles in the innate nasal mucosal response to several respiratory viruses.

6 Dec 2022

Higher dose of new antimalarial drug reduces disease recurrence by 85%

A new antimalarial drug is being introduced at a dose that is too low to be effective for all patients who need it, according to a report published today in eLife.

6 Dec 2022

How two structurally different lemon pectins modulate the gut microbiota

A diet containing fruits and vegetables contains pectins (plant polysaccharides). Pectin cannot be metabolized by mammalian cells in the gastrointestinal tract but is fermented by the gut microbiota in the colon, where short-chain fatty acids (SCFAs) are released. Previous studies have examined pectin's prebiotic properties.

4 Dec 2022

Collaborative work unravels hidden molecular secrets of age-related diseases

Insilico Medicine, a clinical-stage end-to-end artificial intelligence (AI)-driven drug discovery company, and the University of Copenhagen announced today the release of the first batch of results from the collaborative work directed to perform multi-omics-based analyses in the context of age-related diseases using an AI-driven target and drug discovery pipeline.

2 Dec 2022

Researchers develop a self-powered ingestible sensor system to monitor intestinal metabolites

Engineering researchers have developed a battery-free, pill-shaped ingestible biosensing system designed to provide continuous monitoring in the intestinal environment.

1 Dec 2022

Integrated approach addresses some of the biggest challenges in natural products drug discovery

Many successful drugs have their origins in natural sources such as plants, fungi, and bacteria, but screening natural products to identify potential drugs remains a difficult undertaking.

1 Dec 2022

Grape consumption protects against ultraviolet UV damage to the skin

A recent human study published this week in the scientific journal Antioxidants found that consuming grapes protected against ultraviolet (UV) damage to the skin. Study subjects showed increased resistance to sunburn after consuming 2 ¼ cups of grapes every day for two weeks.

30 Nov 2022

Metabolites News and Research

Gut-dwelling bacteria can promote the desire to exercise, study shows

What is the role of the pediatric gut microbiome in COVID-19?

Study examines the role of brain-gut microbiome system in discrimination-related health issues

Nanomaterial can indirectly affect the immune system via the gut microbiome, study shows

What are the associations of metabolome, microbiome, and immune perturbations with severe COVID-19?

Understanding why respiratory infections are more common in the winter

Higher dose of new antimalarial drug reduces disease recurrence by 85%

How two structurally different lemon pectins modulate the gut microbiota

Collaborative work unravels hidden molecular secrets of age-related diseases

Researchers develop a self-powered ingestible sensor system to monitor intestinal metabolites

Integrated approach addresses some of the biggest challenges in natural products drug discovery

Grape consumption protects against ultraviolet UV damage to the skin

New urinary biomarkers could help monitor potential abuse of emerging synthetic cannabinoids

Broccoli and sprouts improve gut microbiota and reduce inflammation in IBD

Glycan signatures in rheumatic diseases and their associated functional implications

The production, metabolism, and inhibition of heterocyclic aromatic amines produced from cooking meat

Wireless smart bandage promotes faster closure of wounds, enhances skin recovery

Maternal obesity during pregnancy causes metabolic perturbations in offspring's liver and skeletal muscle

Study identifies enlarged perivascular spaces in the brains of migraine sufferers

Unique resource for identifying new biomarkers of environmental exposures in early life

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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