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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Mayo Clinic, Hitachi to build North America's first carbon ion treatment facility

Mayo Clinic and Hitachi, Ltd. have reached an agreement in principle to build a carbon ion treatment facility as part of Mayo Clinic's recently announced integrated oncology facility which will be constructed at Mayo Clinic's campus in Jacksonville, Florida.

19 Nov 2019

New database helps identify therapeutic targets to fight infectious diseases

Infectious diseases are caused by pathogenic microorganisms capable of entering, colonizing and growing within a host organism, thus producing an infection. Bacterial infections have been on the rise worldwide in recent years, but many mechanisms underlying bacterial pathogenesis are still poorly understood.

19 Nov 2019

Researchers merge 3D/4D printing with a chemical process to produce 'living' materials

Repairing and reusing plastics and delivering cancer drugs more effectively are only two of many of the potential applications a new 3D/4D printing technology might have, thanks to the pioneering work of a research collaboration between UNSW Sydney and The University of Auckland.

19 Nov 2019

Scientists develop new therapy for acute myeloid leukemia

Cold Spring Harbor Laboratory scientists, with chemists and cancer biologists from Dana-Farber Cancer Institute, have developed a new therapy that extended the survival of mice with acute myeloid leukemia.

19 Nov 2019

CTF, DELopen jointly offer unique opportunities to neurofibromatosis research community

The Children's Tumor Foundation, an innovative and global neurofibromatosis (NF) research foundation announced today a collaboration with DELopen, a DNA-encoded library technology platform sponsored by WuXi AppTec, a leading global provider of R&D and manufacturing services enabling companies in the pharmaceutical, biotechnology and medical device industries.

19 Nov 2019

U.S. Army project may lead to new class of self-healing materials and therapeutics for soldiers

Synthetic biologists working on a U.S. Army project have developed a process that could lead to a new class of synthetic polymers that may create new high-performance materials and therapeutics for Soldiers.

18 Nov 2019

'Dysbiosis' promotes the onset of colorectal cancer

The gastroenterology team at Henri-Mondor AP-HP Hospital and University Paris-Est Créteil, led by Professor Iradj Sobhani, together with teams from Inserm and the Institut Pasteur Molecular Microbial Pathogenesis Unit (U1202), led by Professor Philippe Sansonetti - holder of the Microbiology and Infectious Diseases Chair at the Collège de France -, have demonstrated that an imbalance in the gut microbiota, also known as "dysbiosis", promotes the onset of colorectal cancer.

18 Nov 2019

Researchers identify “mutational footprint” caused by chemotherapy that leads to side effects

Researchers have characterized the "mutational footprint" that results from chemotherapy and leads to long-term side effects.

18 Nov 2019

Vaping wrecks immune cell function, increases infection risk

A new study published in the Journal of the American College of Cardiology shows that e-cigarettes have toxic effects on neutrophils function, making them a threat to human health by increasing the likelihood of infection with Gram-negative bacteria.

17 Nov 2019

Rare DNA variants linked to sudden cardiac death

Sudden cardiac death affects 220,000 U.S. adults annually, most of whom have no prior symptoms of a heart issue.

17 Nov 2019

Research breakthrough may lead to new therapeutic targets for cancers

Computational modeling is the use of computers to simulate and study the behavior of complex systems. Computational approaches are widely adopted in the bioimedical sciences and can be used to sift through large volumes of complex data to extract recurrent patterns that may point to a disease's causes and effects.

15 Nov 2019

Mining 'darkest' parts of the genome in cancer cells yields gold

Mining the rich uncharted territory of the genome or genetic material of a cancer cell has yielded gold for Princess Margaret scientists: new protein targets for drug development against prostate cancer.

15 Nov 2019

Lab Innovations 2019 achieves record breaking numbers

Lab Innovations celebrated its 8th edition on 30 & 31 October 2019, trumping all records for the event. Attracting 3,860 attendees - an impressive 24% increase on the previous year - this makes it the largest Lab Innovations to date.

From Lab Innovations 15 Nov 2019

Research shows how bacteria associated with Crohn's disease tolerate antibiotics

Bacteria associated with Crohn's disease rely on multiple stress responses to survive, multiply, and tolerate antibiotics within white blood cells called macrophages, according to a study published November 14 in the open-access journal PLOS Pathogens by Olivier Espéli of the College de France and PSL Research University in Paris, France, and colleagues.

14 Nov 2019

Non-coding enhancer DNA may be key for identifying genetic risk in neurological conditions

One might think that the primary cause of most genetically linked diseases comes from mutations in coding DNA -- alterations in coding regions of the genome that can lead directly to changes in the expression of particular proteins important for a healthy body.

14 Nov 2019

Altering malarial parasite genes to prevent malaria

Malaria is a mosquito-borne disease caused by the parasitic organism called Plasmodium, of which there are several types that cause the different kinds of malarial fever. This age-old infection still kills over 400,000 people every year, all over the world. A new study published in the journal Cell on November 14, 2019, shows how a simple tweaking of the genes of this organism could quite conceivably lead to the elimination of this disease altogether.

14 Nov 2019

Lithium corrects radiation damage to brain in young cancer patients

A new study on mice, published online in the journal Molecular Psychiatry, on November 14, 2019, shows that the intermittent use of lithium, which is widely used to stabilize the mood in conditions such as bipolar disorder, can correct memory and learning losses due to radiation therapy to the brain in very young animals, even when the lithium is given long after the injury.

14 Nov 2019