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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Botswana now the origin of humans

A group of scientists have reported their new theory that human life was first seen in northern Botswana, south of the Zambezi river in Africa, according to their article published in the journal Nature.

29 Oct 2019

Polygenic scoring system shows promise to predict depression risk and resilience under stress

Depression doesn't come from one gene, one life event, or one personality trait. That's what makes it so hard to predict, prevent or treat effectively.

29 Oct 2019

Landmark study pinpoints the birthplace of modern humans

A landmark study led by Sydney researchers pinpoints the birthplace of modern humans in southern Africa and suggests how climate change may have driven the first migrations.

29 Oct 2019

Researchers develop new test to detect nutrient deficiencies in harsh environments

Mothers and children in low resource communities may appear well fed but often suffer from micronutrient deficiencies.

29 Oct 2019

Researchers develop new genomic analysis method for identifying Yersinia strains

The Yersinia genus covers a vast range of bacteria that are distinguished by criteria such as whether or not they are able to cause disease (their pathogenicity).

29 Oct 2019

Femtogenix announces new data on ADCs containing reduced potency payloads in solid tumor models

Femtogenix Ltd, a UK biotechnology company developing the next generation of DNA-interactive Antibody Drug Conjugate payloads, today announced data demonstrating the potent efficacy and favorable toxicity profile of a reduced potency analogue from its Pyridinobenzodiazepine ADC payload platform in solid tumor models.

From Pheon Therapeutics 29 Oct 2019

Researchers reconstruct the evolutionary history of metabolism

By analyzing how metabolic enzymes are built and organized, researchers have reconstructed the evolutionary history of metabolism. Their study shows how metabolic networks - which drive every cellular process from protein building to DNA repair - became less random, more modular and more hierarchical over time, the researchers say.

29 Oct 2019

Novel antibodies could provide a universal flu vaccine

Now, a new study published in the journal Science on October 25, 2019, reports on a set of three novel antibodies that bind to another type of viral cell surface antigen called neuraminidase (NA) that is necessary for viral replication.

28 Oct 2019

Some types of proteins can stabilize damaged DNA

At the University of Copenhagen, researchers have discovered how some types of proteins stabilize damaged DNA and thereby preserve DNA function and integrity. This new finding also explains why people with inborn or acquired defects in certain proteins cannot keep their DNA stable and develop diseases such as cancer.

28 Oct 2019

MPST enzyme levels in hair could be a good biomarker for schizophrenia

Working with model mice, post-mortem human brains, and people with schizophrenia, researchers at the RIKEN Center for Brain Science in Japan have discovered that a subtype of schizophrenia is related to abnormally high levels hydrogen sulfide in the brain.

28 Oct 2019

Molecular mechanisms involved in Pixantrone's interactions with cancer DNA discovered

Recently, a drug named Pixantrone (PIX) was developed, which is far less damaging to the heart than previous, less advanced compounds. PIX is now used to treat cancers including non-Hodgkin's lymphoma and leukaemia, but a detailed knowledge of the molecular processes it uses to destroy cancer cells has been lacking so far.

28 Oct 2019

How the SETD1A gene produces schizophrenia in mice

A new study published in the journal Neuron on October 9, 2019 reports that scientists have unlocked part of the secrets of the SETD1A gene – how mutations in the gene put the individual at risk for the condition.

26 Oct 2019

Gut microbiome altered by burn injury and influenced by fluid resuscitation, study shows

Major burns lead to changes in the gastrointestinal tract bacteria, and these alterations of the gut microbiome are influenced by resuscitation with intravenous (IV) fluids, according to animal studies reported in SHOCK: Injury, Inflammation, and Sepsis: Laboratory and Clinical Approaches, Official Journal of theShockSociety. The journal is published in the Lippincott portfolio by Wolters Kluwer.

25 Oct 2019

Study finds molecular key to formation of mature and fully functioning T cells

In a finding that could help lead to new therapies for immune diseases like multiple sclerosis and IBD, scientists report in the Journal of Experimental Medicine identifying a gene and family of proteins critical to the formation of mature and fully functioning T cells in the immune system.

25 Oct 2019

Researchers discover how the body repairs damaged DNA

Researchers from the University of Copenhagen have made an extraordinary discovery in how the body repairs damaged DNA, which can lead to better understanding and management of diseases such as cancer.

25 Oct 2019

NYU Langone Health launches new molecular assay to identify patients with brain tumors

NYU Langone Health and its Perlmutter Cancer Center have launched clinical whole genome DNA methylation profiling for patients with brain tumors.

24 Oct 2019

Scientists pinpoint epigenetic differences in the way lupus affects black women

Scientists at the HudsonAlpha Institute for Biotechnology have pinpointed epigenetic differences in the way lupus affects black women compared to other lupus patients, revealing important mechanics of the puzzling disease.

24 Oct 2019

Gut microbiome is a reality in fetal life also

A study published in the Journal of Clinical Investigation shows that in both mice and humans, the fetal gut has its own microbiome, which is probably derived straight from the maternal organism.

24 Oct 2019

Genetically definable subgroups of cancers sensitive to treatment

Precision oncology aims to use genetic features of a patient's tumor to tailor anti-cancer therapy. DNA mutations in a drug target have provided a number of therapeutic opportunities; however, there are many cancer types that do not have obvious targetable mutations.

24 Oct 2019

Parents' behavior can have substantial impact on developing oxytocin systems in babies

Oxytocin is an extremely important hormone, involved in social interaction and bonding in mammals, including humans.

24 Oct 2019

DNA News and Research

Further Reading

Botswana now the origin of humans

Polygenic scoring system shows promise to predict depression risk and resilience under stress

Landmark study pinpoints the birthplace of modern humans

Researchers develop new test to detect nutrient deficiencies in harsh environments

Researchers develop new genomic analysis method for identifying Yersinia strains

Femtogenix announces new data on ADCs containing reduced potency payloads in solid tumor models

Researchers reconstruct the evolutionary history of metabolism

Novel antibodies could provide a universal flu vaccine

Some types of proteins can stabilize damaged DNA

MPST enzyme levels in hair could be a good biomarker for schizophrenia

Molecular mechanisms involved in Pixantrone's interactions with cancer DNA discovered

How the SETD1A gene produces schizophrenia in mice

Gut microbiome altered by burn injury and influenced by fluid resuscitation, study shows

Study finds molecular key to formation of mature and fully functioning T cells

Researchers discover how the body repairs damaged DNA

NYU Langone Health launches new molecular assay to identify patients with brain tumors

Scientists pinpoint epigenetic differences in the way lupus affects black women

Gut microbiome is a reality in fetal life also

Genetically definable subgroups of cancers sensitive to treatment

Parents' behavior can have substantial impact on developing oxytocin systems in babies

eBook: A guide to RNA sequencing eBook

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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