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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Discovery of neoantigens could widen the possibilities for universal cancer vaccine

For more than a decade, scientist Stephen Albert Johnston and his team at Arizona State University's Biodesign Institute have pooled their energies into an often scoffed-at, high-risk, high-reward goal in medicine: to develop a universal vaccine to prevent cancer.

2 Oct 2019

New leishmaniasis look-alike parasitic infection reported

A new study published online in the journal Emerging Infectious Diseases describes the appearance of a new protozoan infection carried by insects which causes symptoms that mimic the disease called visceral leishmaniasis, caused by a different parasite.

2 Oct 2019

New study shows response to HIV vaccine in 6 weeks

A new study using DNA-based and protein HIV vaccines in various combinations shows that antibody and cellular immune response occurs within 6 weeks from the date of vaccination, and the combination must be administered together for the most rapid protection. This will enable more large-scale testing of the vaccine for effectiveness. About 40 million people today have HIV infections, and 1.2 million deaths a year are related to this infection.

1 Oct 2019

UC associate professor receives NCI grant to study small RNAs in breast cancer metastasis

Xiaoting Zhang, PhD, associate professor of cancer biology at the University of Cincinnati College of Medicine, received federal funding, an R01 grant from the National Cancer Institute, to study certain genetic material, known as small RNAs, in breast cancer metastasis (or spread).

1 Oct 2019

Researchers to explore if humans can exploit genetics of a mouse that regrows axons after injury

A bit more than a million years ago, a population of Southeastern Asian mice developed the remarkable ability to regrow axons after injury to its brain.

1 Oct 2019

New study helps better understand how type 2 diabetes progresses as a disease

Researchers at Joslin Diabetes Center, an affiliate of Harvard Medical School, have unlocked the key to clearly identifying diseased beta cells in type 2 diabetes.

1 Oct 2019

Detecting neurocognitive change in children with acute lymphoblastic leukemia

Although cure rates for children with cancer are increasing, cancer treatments can cause permanent deterioration of brain functions leading to impairments in attention, concentration, memory and learning. As a result, these changes can lead to challenges with school, obtaining future employment and overall quality of life into adulthood, even though cancer treatment may have been successful.

1 Oct 2019

Researchers confront mystery of tropical fungal outbreak in the Pacific Northwest

The Great Alaskan Earthquake of 1964 and the tsunamis it spawned may have washed a tropical fungus ashore, leading to a subsequent outbreak of often-fatal infections among people in coastal regions of the Pacific Northwest, according to a paper co-authored by researchers at the Johns Hopkins Bloomberg School of Public Health and the nonprofit Translational Genomics Research Institute, an affiliate of City of Hope.

1 Oct 2019

Research: Potentially harmful microbes overwhelm healthy gut microbiota in ICU patients

Potentially harmful microbes overwhelm the healthy gut microbiota in intensive care patients, research has found.

1 Oct 2019

Why granny’s herbs work to lower high blood pressure

A study from the University of California, Irvine, explains a hitherto unknown mechanism of action for bioactive molecules in commonly used plant-based folk medicines like fennel, camomile and lavender that are used to lower the blood pressure.

1 Oct 2019

Horizon Discovery announces full commercial licensing of GS knockout CHO K1 cell line to Glenmark

Horizon Discovery Group plc, a global leader in the application of gene editing and gene modulation for cell line engineering, today announced the full commercial licensing to Glenmark Pharmaceuticals, a global innovative pharmaceutical company, of its gene-edited Glutamine Synthetase knockout Chinese Hamster Ovary K1 cell line. Terms of the agreement were based on stringent evaluation of the cell line by Glenmark to assess its suitability for adoption into the Company’s biomanufacturing processes.

From Revvity 30 Sep 2019

New CRISPR-Cas9 variant has potential to increase precision during gene therapy

Researchers have developed a new variant of the gene editing technique CRISPR-Cas9 that has the potential to increase precision during gene therapy in humans.

30 Sep 2019

Modern chemo more effective than second targeted hormone therapy against resistant prostate cancer

A modern chemotherapy drug is more effective for men with advanced prostate cancer than a second targeted hormone therapy in patients who have stopped responding to treatment, a major clinical trial shows.

30 Sep 2019

Breast, ovarian cancer drug more effective than targeted hormone therapy in some men with prostate cancer

A drug used for breast and ovarian cancer is more effective than modern targeted hormone treatments at slowing progression and improving survival in some men with advanced prostate cancer, phase III clinical trial findings reveal.

30 Sep 2019

Cardiac cells derived from skin samples help unravel genetic underpinnings of heart function

Genome-wide association studies have uncovered more than 500 genetic variants linked to heart function, everything from heart rate to irregular rhythms that can lead to stroke, heart failure or other complications.

30 Sep 2019

Using X-ray-nanoparticle interactions for improved radiation therapy

A new study has indicated a new way to deliver locally aggressive radiation therapy in cancer, using the element gadolinium.

30 Sep 2019

Lung cancer may soon be picked up by a blood test

A study presented at the ESMO Congress 2019 has revealed that a blood test may soon be able to pick up circulating tumor DNA to help avoid invasive tissue biopsies in lung cancer patients.

30 Sep 2019

New trial shows improved survival for patients with advanced colorectal BRAF-mutant cancer

A clinical trial has shown that using a combination of three drugs that target a BRAF gene mutation in patients with mCRC effectively boosts overall survival.

30 Sep 2019

A new method to distinguish benign and cancerous skin moles

A new study has reported a cost-effective, more accurate, and less invasive way to diagnose cancerous melanoma cells in skin tumors.

30 Sep 2019

Paving the way towards new cancer radiation therapy using X-rays and nanoparticles

An element called gadolinium delivered into cancer cells releases killer electrons when hit by specially tuned X-rays. The approach, published in the journal Scientific Reports, could pave the way towards a new cancer radiation therapy.

30 Sep 2019

DNA News and Research

Further Reading

Discovery of neoantigens could widen the possibilities for universal cancer vaccine

New leishmaniasis look-alike parasitic infection reported

New study shows response to HIV vaccine in 6 weeks

UC associate professor receives NCI grant to study small RNAs in breast cancer metastasis

Researchers to explore if humans can exploit genetics of a mouse that regrows axons after injury

New study helps better understand how type 2 diabetes progresses as a disease

Detecting neurocognitive change in children with acute lymphoblastic leukemia

Researchers confront mystery of tropical fungal outbreak in the Pacific Northwest

Research: Potentially harmful microbes overwhelm healthy gut microbiota in ICU patients

Why granny’s herbs work to lower high blood pressure

Horizon Discovery announces full commercial licensing of GS knockout CHO K1 cell line to Glenmark

New CRISPR-Cas9 variant has potential to increase precision during gene therapy

Modern chemo more effective than second targeted hormone therapy against resistant prostate cancer

Breast, ovarian cancer drug more effective than targeted hormone therapy in some men with prostate cancer

Cardiac cells derived from skin samples help unravel genetic underpinnings of heart function

Using X-ray-nanoparticle interactions for improved radiation therapy

Lung cancer may soon be picked up by a blood test

New trial shows improved survival for patients with advanced colorectal BRAF-mutant cancer

A new method to distinguish benign and cancerous skin moles

Paving the way towards new cancer radiation therapy using X-rays and nanoparticles

eBook: A guide to RNA sequencing eBook

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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