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Vaccine candidate containing tetanus toxoid potentially protective against SARS-CoV-2

Researchers from Cuba, China, and France have demonstrated the potential of coupling a viral antigen with the tetanus toxoid protein as a vaccination approach to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

14 Feb 2021

Using a smartphone-based microscope for detecting single molecules and diagnosing diseases

Biomarkers play a central role in the diagnosis of disease and assessment of its course. Among the markers now in use are genes, proteins, hormones, lipids and other classes of molecules.

13 Feb 2021

New zebrafish model could help advance glioblastoma multiforme research

Scientists at the Fralin Biomedical Research Institute at VTC have identified a new zebrafish model that could help advance glioblastoma multiforme research. Glioblastoma is an aggressive form of primary brain tumor - fewer than one in 20 patients survive five years after diagnosis.

13 Feb 2021

Revolutionary drug combination shows potential for treatment of fatal childhood cancer

Every year around 20 Australian children die from the incurable brain tumor, Diffuse Intrinsic Pontine Glioma (DIPG). The average age of diagnosis for DIPG is just seven years.

13 Feb 2021

Study describes mechanism that limits immunosupressive activity of tumor-associated macrophages

Tumor cells are able to avoid the attack of the immune system through several mechanisms. For instance, these can secrete factors that turn macrophages -cells in the immune system- into dual action agents that contribute to the tumor progress and will protect it from immune body defenses: these become, thus, the tumor-associated macrophages (TAMs).

13 Feb 2021

Star-shaped brain cells may play a key role in stuttering

Astrocytes -- star-shaped cells in the brain that are actively involved in brain function -- may play an important role in stuttering, a study led by a University of California, Riverside, expert on stuttering has found.

12 Feb 2021

A novel approach to suppress the growth of glioblastoma cells

Inhibiting a key enzyme that controls a large network of proteins important in cell division and growth paves the way for a new class of drugs that could stop glioblastoma, a deadly brain cancer, from growing.

12 Feb 2021

Study offers new protocols for high-quality SARS-CoV-2 genomic sequencing

Researchers at the Southern Illinois University, U.S.A. have presented a comprehensive and well-validated set of working protocols for sequencing high-quality SARS-CoV-2 genomes in high throughput from patient samples.

12 Feb 2021

Study reveals detailed map of glioblastoma in genetic, molecular detail

Glioblastoma is among the most aggressive and devastating of cancers. While rare compared with other cancers, it's the most common type of brain cancer.

12 Feb 2021

New article reviews how the circadian clock controls various aspects of homeostasis

Subconsciously, our bodies keep time for us through an ancient means - the circadian clock. A new University of California, Irvine-led article reviews how the clock controls various aspects of homeostasis, and how organs coordinate their function over the course of a day.

12 Feb 2021

Researchers receive $1,894,271 grant to address new drug targets for diastolic dysfunction

After the left ventricle of the heart contracts, it must relax efficiently to prepare to refill and supply the body with blood on the next beat. An increasing number of patients -- including nearly all patients with heart failure -- suffer from impaired relaxation, which is part of a clinical syndrome known as diastolic dysfunction. Currently, treatments for impaired relaxation do not exist.

12 Feb 2021

Implant improves quality of life in patients with bilateral vestibular hypofunction

Getting around without the need to concentrate on every step is something most of us can take for granted because our inner ears drive reflexes that make maintaining balance automatic.

12 Feb 2021

New technology can help develop diagnostic tests for multiple sclerosis

Multiple sclerosis (MS) is the most common neurological disease in young adults, affecting more than 2 million individuals worldwide, with about 1500 cases in Estonia. About 20% of MS patients experience optic neuritis (ON) as the presenting symptom, but not all ON patients develop MS.

12 Feb 2021

Portable suitcase lab for rapid detection of SARS-CoV-2

The PCR test is the most accurate tool to identify SARS-CoV-2. However, valid results are often available only after days.

12 Feb 2021

Opioid use during pregnancy can cause long-lasting impairment in the infant's brain

As the number of pregnant women using opioid drugs continues to rise, questions have been raised about the long-term health effects on children exposed to these drugs in the womb.

12 Feb 2021

Researchers identify a pathway used by filoviruses to enter cells

It was once thought that Ebola and related filoviruses were more or less contained to Central Africa.

11 Feb 2021

Ionic liquid formulation kills cancer cells, allows uniform distribution of chemotherapy to tumors

A Mayo Clinic team, led by Rahmi Oklu, M.D., Ph.D., a vascular and interventional radiologist at Mayo Clinic, in collaboration with Samir Mitragotri, Ph.D., of Harvard University, report the development of a new ionic liquid formulation that killed cancer cells and allowed uniform distribution of a chemotherapy drug into liver tumors and other solid tumors in the lab.

11 Feb 2021

Scientists conduct interdisciplinary study on using nanoparticles to fight leukemia

Scientists from Scientific and Educational Center & Smart Materials and Biomedical Applications under the leadership of Kateryna Levada together with colleagues from Center for Immunology and Cellular Biotechnology of the Immanuel Kant Baltic Federal University conducted a joint interdisciplinary study on the development of a new method for treating leukemia using nanomaterials.

11 Feb 2021

STING activation may be a new approach to reduce graft-versus-host disease

MUSC Hollings Cancer Center researcher Yongxia Wu, Ph.D., identified a new target molecule in the fight against graft-versus-host disease (GVHD).

11 Feb 2021

Use of mobile stroke units linked to improved clinical outcomes

STEMOs (Stroke-Einsatz-Mobile) have been serving Berlin for ten years. The specialized stroke emergency response vehicles allow physicians to start treating stroke patients before they reach hospital.

11 Feb 2021

Laboratory News and Research

Vaccine candidate containing tetanus toxoid potentially protective against SARS-CoV-2

Using a smartphone-based microscope for detecting single molecules and diagnosing diseases

New zebrafish model could help advance glioblastoma multiforme research

Revolutionary drug combination shows potential for treatment of fatal childhood cancer

Study describes mechanism that limits immunosupressive activity of tumor-associated macrophages

Star-shaped brain cells may play a key role in stuttering

A novel approach to suppress the growth of glioblastoma cells

Study offers new protocols for high-quality SARS-CoV-2 genomic sequencing

Study reveals detailed map of glioblastoma in genetic, molecular detail

New article reviews how the circadian clock controls various aspects of homeostasis

Researchers receive $1,894,271 grant to address new drug targets for diastolic dysfunction

Implant improves quality of life in patients with bilateral vestibular hypofunction

New technology can help develop diagnostic tests for multiple sclerosis

Portable suitcase lab for rapid detection of SARS-CoV-2

Opioid use during pregnancy can cause long-lasting impairment in the infant's brain

Researchers identify a pathway used by filoviruses to enter cells

Ionic liquid formulation kills cancer cells, allows uniform distribution of chemotherapy to tumors

Scientists conduct interdisciplinary study on using nanoparticles to fight leukemia

STING activation may be a new approach to reduce graft-versus-host disease

Use of mobile stroke units linked to improved clinical outcomes

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