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New program could advance translation of research, improve lives of older adults

In this digital age, where the internet accelerates technological development, there has been a surge of scientific innovation designed to improve the quality of life for patients in need.

9 Feb 2021

Pancreatic β cells secrete miR-29 in response to high levels of free fatty acids

In a new study published in Journal of Extracellular Vesicles, Chen-Yu Zhang's group and Antonio Vidal-Puig's group at University of Cambridge report that pancreatic β cells secrete miR-29 family members (miR-29a, miR-29b and miR-29c) in response to high levels of free fatty acids (FFAs). These β cell-derived miR-29s are delivered to the liver, promoting insulin resistance and enhancing hepatic glucose output.

9 Feb 2021

New platform could help advance genomic medicine research, drug discovery

A Cleveland Clinic-led team of researchers has developed a personalized genomic medicine platform that will help advance accelerate genomic medicine research and genome-informed drug discovery, according to new study results published recently in Genome Biology.

8 Feb 2021

Compound isolated from Ophiura sarsii can be used as an affordable drug for photodynamic therapy

An unusual biologically active porphyrin compound was isolated from seabed dweller Ophiura sarsii. The substance might be used as an affordable light-sensitive drug for innovative photodynamic therapy and for targeted treatment of triple-negative breast cancer and some other cancers.

8 Feb 2021

Take-at-home tests increase colorectal cancer screening rates by more than 1,000%

Colorectal cancer screening rates jumped by more than 1,000 percent when researchers sent take-at-home tests to patients overdue for testing at a community health center that predominantly serves people of color.

8 Feb 2021

Researchers find new clues to how SARS-CoV-2 infects cells

The molecular details of how SARS-CoV-2 enters cells and infects them are still not clear. Researchers at Uppsala University have tested the bioinformatic predictions made by another research group and have identified receptors that could be important players in the process.

8 Feb 2021

Brain protein responsible for causing Alzheimer's disease also plays a protective role

Findings from a new study on Alzheimer's disease (AD), led by researchers at the University of Saskatchewan, could eventually help clinicians identify people at highest risk for developing the irreversible, progressive brain disorder and pave the way for treatments that slow or prevent its onset.

8 Feb 2021

Study implicates disruption in prenatal neurogenesis in the development of ASDs

A new study of autism risk genes by UC San Francisco and UC Berkeley scientists implicates disruption in prenatal neurogenesis - a process in which specialized "progenitor" cells give rise to new brain cells - in the development of autism spectrum disorders (ASDs).

8 Feb 2021

Bernese researchers develop a second generation lung-on-chip

The lung is a complex organ whose main function is to exchange gases. It is the largest organ in the human body and plays a key role in the oxygenation of all the organs.

8 Feb 2021

Why the U.S. is underestimating Covid reinfection

Kaitlyn Romoser first caught Covid-19 in March, likely on a trip to Denmark and Sweden, just as the scope of the pandemic was becoming clear. Romoser, who is 23 and a laboratory researcher in College Station, Texas, tested positive and had a few days of mild, coldlike symptoms.

8 Feb 2021

Novel plastic film can deactivate 99.99% of the new coronavirus in 15 minutes

A consortium comprised by companies Braskem, AplFilm and Nanox and the UFSCar (Brazil) and Jaume I of Castellón (Spain) universities have released a plastic film capable of deactivating 99.99% of the new coronavirus in 15 minutes.

8 Feb 2021

New technique reveals cellular forces involved in biological tissue formation and growth

A team of Brown University researchers developed a technique that uses tiny polymer spheres to sense the forces at play as body tissue forms and grows.

8 Feb 2021

Study finds structural similarities between SARS-CoV-2 and pangolin coronavirus

Scientists at the Francis Crick Institute have found important structural similarities between SARS-CoV-2 and a pangolin coronavirus, suggesting that a pangolin coronavirus could infect humans.

7 Feb 2021

Discovery of ‘Achilles heel’ in gut bacteria may lead to targeted therapies for Crohn’s disease

The discovery of an "Achilles heel" in a type of gut bacteria that causes intestinal inflammation in patients with Crohn's disease may lead to more targeted therapies for the difficult to treat disease, according to Weill Cornell Medicine and NewYork-Presbyterian investigators.

6 Feb 2021

Small wearable sensor can detect stress biomarker in sweat

We've all felt stressed at some point, whether in our personal or professional lives or in response to exceptional circumstances like the COVID-19 pandemic. But until now there has been no way to quantify stress levels in an objective manner.

6 Feb 2021

Novel hybrid device to boost research on metastatic process of breast cancer cells

European researchers are working on a novel hybrid device to better understand the metastatic process of cancer cells travelling from breast to bone and fast screen new drugs against it.

6 Feb 2021

FDA continues to support the development of medical products to tackle new virus variants

As the public health agency responsible for regulating medical products, we must ensure that health care providers have the most up-to-date diagnostics, treatments and vaccines in their toolbox to fight this pandemic.

5 Feb 2021

Researchers explore the origin of the body axis in animals

Egg cells start out as round blobs. After fertilization, they begin transforming into people, dogs, fish, or other animals by orienting head to tail, back to belly, and left to right.

5 Feb 2021

New method can help evaluate potential sight-preserving properties

Scientists like the John A. Moran Eye Center's Paul S. Bernstein, MD, PhD, know a special class of lipids, or fatty acids, found in the retina of the eye and in just a few other parts of the body play an important role in maintaining vision.

5 Feb 2021

GLS1 inhibitor selectively eliminates senescent cells, ameliorates age-associated disorders

Senescent cells accumulate in organs during aging, promote tissue dysfunction, and cause numerous aging-related diseases like cancer. The cells arise through a process called "cellular senescence," a permanent cell cycle arrest resulting from multiple stresses.

5 Feb 2021

Laboratory News and Research

New program could advance translation of research, improve lives of older adults

Pancreatic β cells secrete miR-29 in response to high levels of free fatty acids

New platform could help advance genomic medicine research, drug discovery

Compound isolated from Ophiura sarsii can be used as an affordable drug for photodynamic therapy

Take-at-home tests increase colorectal cancer screening rates by more than 1,000%

Researchers find new clues to how SARS-CoV-2 infects cells

Brain protein responsible for causing Alzheimer's disease also plays a protective role

Study implicates disruption in prenatal neurogenesis in the development of ASDs

Bernese researchers develop a second generation lung-on-chip

Why the U.S. is underestimating Covid reinfection

Novel plastic film can deactivate 99.99% of the new coronavirus in 15 minutes

New technique reveals cellular forces involved in biological tissue formation and growth

Study finds structural similarities between SARS-CoV-2 and pangolin coronavirus

Discovery of ‘Achilles heel’ in gut bacteria may lead to targeted therapies for Crohn’s disease

Small wearable sensor can detect stress biomarker in sweat

Novel hybrid device to boost research on metastatic process of breast cancer cells

FDA continues to support the development of medical products to tackle new virus variants

Researchers explore the origin of the body axis in animals

New method can help evaluate potential sight-preserving properties

GLS1 inhibitor selectively eliminates senescent cells, ameliorates age-associated disorders

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