Laboratory News and Research

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Genetic interactions may shed light on NGLY1 deficiency

In 2012, four-year-old Bertrand Might became the first-ever patient diagnosed with a rare genetic disorder called N-glycanase (NGLY1) deficiency. The discovery of this condition and Bertrand's diagnosis allowed doctors to look for other children with the same genetic defect. Since then, more than 60 additional patients have been found.

26 Jan 2021

Microwaves used to inactivate aerosolized pathogens

As the pandemic has continued to spread globally, studies indicate the COVID-19 virus may be contained in aerosols that can be generated and spread through breathing, coughing, sneezing, or talking by infected individuals.

26 Jan 2021

New recommendations to improve apps for controlling and monitoring NTDs

A study performed by the Universitat Oberta de Catalunya provided eight recommendations for improving the online technology to help with the treatment and diagnosis of neglected tropical diseases (NTDs).

26 Jan 2021

SARS-CoV-2 rapidly adapts to Vero E6 cell culture propagation

Researchers at the Erasmus Medical Centre in the Netherlands and the University of Illinois at Urbana-Champaign in the US found that SARS-CoV-2 rapidly adapts to Vero E6 cell culture propagation and that this can be prevented by using cell lines with an active serine protease-mediated entry pathway.

26 Jan 2021

Hyperinflammatory conditions drive gender differences in COVID-19 severity and mortality

Recently researchers from India analyzed gender differences in COVID-19-related hyperinflammatory conditions resulting in mortality in Indian patients. The study is published on the preprint server, medRxiv*.

25 Jan 2021

DARPA funding brings wireless communication between brains one step closer to reality

Wireless communication directly between brains is one step closer to reality thanks to $8 million in Department of Defense follow-up funding for Rice University neuroengineers.

25 Jan 2021

Study shows link between early brainstem tau accumulation and cortical hyperexcitability

Study conducted by researchers from the GIGA CRC In vivo Imaging laboratory at ULiège demonstrates, for the first time in humans, how the first deposits of tau proteins in the brainstem are associated with neurophysiological processes specific to the early stages of Alzheimer's disease development.

25 Jan 2021

New, highly accurate 20-minute COVID-19 test is trialed across the University of Surrey

A new, highly accurate COVID-19 test, Virus Hunter 6 (VH6), which delivers results in under 20 minutes is being trialed across the University of Surrey, this week.

25 Jan 2021

UNSW develops a ceramic-based ink to 3D-print bone parts with living cells

3D printers may one day become a permanent fixture of the operating theatre after UNSW scientists showed they could print bone-like structures containing living cells.

25 Jan 2021

Socioeconomic conditions linked to high viral load despite treatment for HIV patients in Ethiopia

For those who are diagnosed and have begun treatment for HIV, it is standard practice to regularly monitor viral load in the blood to assess response to treatment.

25 Jan 2021

Promising nanobodies against COVID-19 produced by llamas

News-Medical speaks to Dr. David Brody about his latest research that involved discovering nanobodies produced by llamas that could help combat coronavirus.

25 Jan 2021

Second-generation double antibody protects from SARS-CoV-2 and its tested variants

The Institute for Research in Biomedicine (IRB; Bellinzona, Switzerland), affiliated to the Università della Svizzera italiana (USI) developed a second-generation 'double antibody' that protects from SARS-CoV-2, the virus causing COVID-19, and all its tested variants. It also prevents the virus from mutating to resist the therapy.

24 Jan 2021

Corning to highlight newest products in 3D cell culture portfolio at SLAS2021

Corning Incorporated will highlight its latest technologies that support the advancement of 3D cell culture, automation, and drug discovery at this year's virtual Society for Laboratory Automation and Screening (SLAS) conference on Jan. 25 through 27.

22 Jan 2021

UC research team uses zebrafish to study a gene mutation that causes congenital scoliosis

Popular in aquariums all over the world, the zebrafish is native to South Asia. But here in a Cincinnati Children's laboratory, the freshwater variant plays a vital role in scientific discovery.

22 Jan 2021

Researchers identify protein that may represent a safer treatment target for pancreatic cancer

Researchers from Queen Mary University of London, have identified a protein that may represent a novel therapeutic target for the treatment of pancreatic cancer.

22 Jan 2021

Treating 'fetus as the patient' could reduce the incidence of pre-term labor and premature birth

The results of a study by researchers at the University of Texas Medical Branch may pave the way for a new medicine delivery system that could reduce the incidence of pre-term labor and premature birth by allowing physicians to treat the 'fetus as the patient'.

22 Jan 2021

NSAIDs dampen antibody and inflammatory responses to SARS-CoV-2 infection in mice

New research shows that non-steroidal anti-inflammatory drugs (NSAIDs) reduced both antibody and inflammatory responses to SARS-CoV-2 infection in mice. The study appears this week in the Journal of Virology, a publication of the American Society for Microbiology.

22 Jan 2021

Pancreatic β cell-derived exosomal miR-29s manipulate glucose homeostasis

In a new study published in Journal of Extracellular Vesicles, Chen-Yu Zhang's group at Nanjing University, School of Life Sciences, and Antonio Vidal-Puig's group at University of Cambridge report that pancreatic β cells secrete miR-29 family members (miR-29s) via exosomes in response to high levels of free fatty acids (FFAs).

22 Jan 2021

Does hypertension always lead to severe COVID-19?

Researchers have developed some prognostic factors to predict the severity of COVID-19 among hypertensive patients.

22 Jan 2021

EKF opens larger facility to increase production of key component for COVID-19 testing regime

EKF’s new facilities in Llandough, Cardiff, for the manufacture of PrimeStore® MTM viral transport media, enabling pathogenic samples to be collected and transported safely and easily in compliance with UN3373 packaging regulations.

From EKF Diagnostics 22 Jan 2021

Laboratory News and Research

Genetic interactions may shed light on NGLY1 deficiency

Microwaves used to inactivate aerosolized pathogens

New recommendations to improve apps for controlling and monitoring NTDs

SARS-CoV-2 rapidly adapts to Vero E6 cell culture propagation

Hyperinflammatory conditions drive gender differences in COVID-19 severity and mortality

DARPA funding brings wireless communication between brains one step closer to reality

Study shows link between early brainstem tau accumulation and cortical hyperexcitability

New, highly accurate 20-minute COVID-19 test is trialed across the University of Surrey

UNSW develops a ceramic-based ink to 3D-print bone parts with living cells

Socioeconomic conditions linked to high viral load despite treatment for HIV patients in Ethiopia

Promising nanobodies against COVID-19 produced by llamas

Second-generation double antibody protects from SARS-CoV-2 and its tested variants

Corning to highlight newest products in 3D cell culture portfolio at SLAS2021

UC research team uses zebrafish to study a gene mutation that causes congenital scoliosis

Researchers identify protein that may represent a safer treatment target for pancreatic cancer

Treating 'fetus as the patient' could reduce the incidence of pre-term labor and premature birth

NSAIDs dampen antibody and inflammatory responses to SARS-CoV-2 infection in mice

Pancreatic β cell-derived exosomal miR-29s manipulate glucose homeostasis

Does hypertension always lead to severe COVID-19?

EKF opens larger facility to increase production of key component for COVID-19 testing regime

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