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Researchers develop saliva testing method for SARS-CoV-2 using robotic RNA extraction

Researchers have developed an automated method of RNA extraction from saliva samples to allow faster processing times and high test sensitivity. Saliva testing could be used as an alternative to swab testing for coronavirus disease 2019 (COVID-19) surveillance.

12 Jan 2021

Advanced humanized mouse model helps better understand immunotherapy resistance in melanoma

Scientists at The Wistar Institute have created an advanced humanized immune system mouse model that allows them to examine resistance to immune checkpoint blockade therapies in melanoma. It has revealed a central role for mast cells. These findings were published today in the journal Nature Communications.

12 Jan 2021

New fluorescence microscopy technique produces nanoscale 3D images of living cells

A new fluorescence microscopy technique has produced the world's first nanoscale 3D images of molecules in a whole, living cell, researchers at KTH Royal Institute of Technology reported.

12 Jan 2021

Headache as COVID-19 symptom could indicate milder disease, study finds

Researchers at the Hospital Universitario de La Princes in Madrid, Spain, found that patients with COVID-19 who developed headaches as an early symptom of infection had a milder illness and less risk of death.

12 Jan 2021

Mindfulness training program could be used to prevent police suicide

The Labpsitec laboratory of the University of Valencia, in collaboration with the H-Policía association has put the effects of a police-specific mindfulness training programme to the test.

12 Jan 2021

Researchers determine the atomic structure of protein that helps coronavirus to evade immune cells

A team of HIV researchers, cellular biologists, and biophysicists who banded together to support COVID-19 science determined the atomic structure of a coronavirus protein thought to help the pathogen evade and dampen response from human immune cells.

12 Jan 2021

Wearable heart monitors and deep learning can provide early warning of SARS-CoV-2 infection

A recent study, appearing as a preprint on the medRxiv* server, reveals the possibility of early prediction of SARS-CoV-2 infection using data on the resting heart rate in the presymptomatic period.

12 Jan 2021

ARID1A gene in ovarian cancer plays a role in the regulation of metabolism

Mutations that inactivate the ARID1A gene in ovarian cancer increase utilization of the glutamine amino acid making cancer cells dependent on glutamine metabolism, according to a study by The Wistar Institute published online in Nature Cancer.

12 Jan 2021

Study could help develop new oral drugs for treating muscular dystrophy, heart failure

Cell-derived exosomes are effective in treating disease when mixed with the dominant protein in breast milk and given orally, a new Smidt Heart Institute study of laboratory mice shows.

12 Jan 2021

Study offers data related to physicians' potential liability to use AI in personalized medicine

Physicians who follow artificial intelligence (AI) advice may be considered less liable for medical malpractice than is commonly thought, according to a new study of potential jury candidates in the U.S.

11 Jan 2021

Study aims to halt further isolation of people aging with HIV during COVID-19 pandemic

The School of Medicine at the University of California, Riverside, has received a grant aimed at halting further isolation of people aging with HIV during the COVID-19 pandemic.

11 Jan 2021

MDC researchers develop a potent weapon against lymphomas

MDC researchers have developed a new approach to CAR T-cell therapy. The team has shown in Nature Communications that the procedure is very effective, especially when it comes to fighting follicular lymphomas and chronic lymphocytic leukemia, the most common type of blood cancer in adults.

11 Jan 2021

Master Regulator proteins control cancer transcriptional identity

Thousands of different genetic mutations have been implicated in cancer, but a new analysis of almost 10,000 patients found that regardless of the cancer's origin, tumors could be stratified in only 112 subtypes and that, within each subtype, the Master Regulator proteins that control the cancer's transcriptional state were virtually identical, independent of the specific genetic mutations of each patient.

11 Jan 2021

Researchers identify bacterium that produces pharmaceutical all-purpose weapon

For some years, an active substance from the leaves of an ornamental plant has been regarded as a possible forerunner of a new group of potent drugs. So far, however, it has been very laborious to manufacture it in large quantities.

11 Jan 2021

Research provides better understanding of how antibiotic resistance arises

Researchers at the Quadram Institute on the Norwich Research Park have shown how the development of antibiotic resistance by bacteria can have 'side-effects' for them including affecting their ability to cause disease.

11 Jan 2021

New type of flour improved the glycemic response of people eating white bread

Researchers from the Quadram Institute and King's College London have shown that replacing wheat flour with a new ingredient derived from chickpeas improved the glycemic response of people eating white bread.

11 Jan 2021

Mogrify enters research collaboration with the MRC Laboratory of Molecular Biology

Mogrify Limited and the MRC Laboratory of Molecular Biology (LMB), today announced an exploratory research collaboration.

11 Jan 2021

Researchers unravel the process that makes viruses infectious

Researchers have for the first time identified the way viruses like the poliovirus and the common cold virus 'package up' their genetic code, allowing them to infect cells.

8 Jan 2021

Single-dose nanoparticle vaccine for SARS-CoV-2

Before the pandemic, the lab of Stanford University biochemist Peter S. Kim focused on developing vaccines for HIV, Ebola and pandemic influenza.

8 Jan 2021

FDA alerts health care providers and clinical laboratory staff about SARS-CoV-2 viral mutation

The U.S. Food and Drug Administration is alerting clinical laboratory staff and health care providers that the FDA is monitoring the potential impact of viral mutations, including an emerging variant from the United Kingdom known as the B.1.1.7 variant, on authorized SARS-CoV-2 molecular tests, and that false negative results can occur with any molecular test for the detection of SARS-CoV-2 if a mutation occurs in the part of the virus's genome assessed by that test.

8 Jan 2021

Laboratory News and Research

Researchers develop saliva testing method for SARS-CoV-2 using robotic RNA extraction

Advanced humanized mouse model helps better understand immunotherapy resistance in melanoma

New fluorescence microscopy technique produces nanoscale 3D images of living cells

Headache as COVID-19 symptom could indicate milder disease, study finds

Mindfulness training program could be used to prevent police suicide

Researchers determine the atomic structure of protein that helps coronavirus to evade immune cells

Wearable heart monitors and deep learning can provide early warning of SARS-CoV-2 infection

ARID1A gene in ovarian cancer plays a role in the regulation of metabolism

Study could help develop new oral drugs for treating muscular dystrophy, heart failure

Study offers data related to physicians' potential liability to use AI in personalized medicine

Study aims to halt further isolation of people aging with HIV during COVID-19 pandemic

MDC researchers develop a potent weapon against lymphomas

Master Regulator proteins control cancer transcriptional identity

Researchers identify bacterium that produces pharmaceutical all-purpose weapon

Research provides better understanding of how antibiotic resistance arises

New type of flour improved the glycemic response of people eating white bread

Mogrify enters research collaboration with the MRC Laboratory of Molecular Biology

Researchers unravel the process that makes viruses infectious

Single-dose nanoparticle vaccine for SARS-CoV-2

FDA alerts health care providers and clinical laboratory staff about SARS-CoV-2 viral mutation

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