Antibodies News and Research

RSS

Avantor launches new Protein A Chromatography Resin – PROchievA – that provides supply chain flexibility and improves downstream purification performance for monoclonal antibodies (mAbs) production

Avantor, Inc., a leading global provider of mission-critical products and services to customers in the life sciences, advanced technologies and applied materials industries, today announced a new recombinant Protein A affinity chromatography resin used to purify antibodies during mAbs production.

From Avantor 20 Mar 2020

Targeting PI3Kβ alone and with combination therapy in PTEN-deficient tumors

The cover for issue 11 of Oncotarget features Figure 6, "Effects of AZD8186 in combination with anti-PD1 on syngeneic models," by Owusu-Brackett, et al.

18 Mar 2020

Who should stay at home due to coronavirus?

COVID-19 is a spreading viral illness, mostly mild but fatal in the sick and elderly. At present, it has affected almost 200,000 people, with nearly 8,000 deaths worldwide. Governments around the world are formulating and executing new guidelines to control the spread of the virus. In the latest guidelines, pregnant women join the list of individuals who must stay away from all social contact for 12 weeks to limit the spread of the virus and deaths due to the illness.

17 Mar 2020

New understanding of signaling molecule interleukin-2 can guide drug discovery efforts

The signaling molecule interleukin-2 (IL-2) has long been known to have powerful effects on the immune system, but efforts to harness it for therapeutic purposes have been hampered by serious side effects.

17 Mar 2020

Scientists use artificial intelligence to create new proteins unseen in nature

Researchers have presented a artificial intelligence method for developing new proteins that have never been seen in nature.

17 Mar 2020

Max Planck researchers identify mechanistic basis of antigen receptor gene assembly

Adaptive immunity is a powerful defense mechanism in vertebrates. A finely tuned interplay of different cell types provides a pathogen-specific immune response to eliminate for example bacteria and viruses.

13 Mar 2020

UK lab looks for volunteers to be infected with coronavirus

Amid the coronavirus disease (COVID-19) pandemic, scientists are asking for healthy volunteers to help in the development of the vaccine. Volunteers will be infected with the two strains of the common coronavirus.

12 Mar 2020

Researchers uncover possible pitfalls of common hormone analysis in animal hair

Similar to humans, wild animals' reaction to disturbance is accompanied by releasing hormones, such as cortisol.

12 Mar 2020

Potential breakthrough in cancer immunotherapy with gasdermin E

A new study published in the journal Nature in March 2020 reports the discovery of a new approach to cancer immunotherapy, which could be useful in many more cancers than at present.

11 Mar 2020

Novel strategy to stop tumors from developing new blood vessels

Scientists at the National Institutes of Health and other institutions have devised a new strategy to stop tumors from developing the new blood vessels they need to grow.

11 Mar 2020

Gut bacteria can accumulate in tumors and improve effectiveness of cancer immunotherapy

Researchers at the University of Texas Southwestern Medical Center and University of Chicago have discovered that bacteria that usually live in the gut can accumulate in tumors and improve the effectiveness of immunotherapy in mice.

10 Mar 2020

Researchers develop a microfluidic chip to help detect prostate cancer

Researchers of Sechenov University together with their colleagues from Australia used the microfluidics technology to develop a device able to isolate cancer cells from urine of patients with prostate cancer.

10 Mar 2020

Study identifies a mutation that triggers deadly amyloidosis

Bone marrow plasma cells produce antibodies. These comprise two long and two short protein chains. The pathological proliferation of plasma cells can lead to an overproduction of the short chains.

10 Mar 2020

Berkeley Lights Launches Cell Line Development 2.0 Workflow to Find Top Clones for Complex Antibody Therapeutics

The Opto™ Cell Line Development 2.0 workflow generates, in just days, the best production cell lines for complex antibody therapeutics.

From Bruker Cellular Analysis 10 Mar 2020

Gene therapy reverses cardiac dysfunction in mice with Barth syndrome

Barth syndrome is a rare metabolic disease in boys caused by mutation of a gene called tafazzin or TAZ. It can cause life-threatening heart failure and also weakens the skeletal muscles, undercuts the immune response, and impairs overall growth.

9 Mar 2020

Levels of sBTLA proteins may be a marker of overall survival in patients with HCC

In the 2020 February 25 issue of Scientific Reports, a research group from the Department of Hepatology in Osaka City University Graduate School of Medicine, Japan reported that levels of a circulating soluble immune checkpoint protein can be used as a potential marker to predict overall survival in patients with advanced HCC.

9 Mar 2020

Gut bacteria can boost effectiveness of cancer immunotherapy, mice study suggests

Could the response to cancer immunotherapy depend on bacteria that originate in the gut and travel to the tumor?

7 Mar 2020

Sphingotec’s bio-ADM can reliably support physicians in identifying high-risk sepsis patients

Diagnostics company SphingoTec GmbH today reported on new data on the utility of endothelial function biomarker bioactive Adrenomedullin

5 Mar 2020

Respiratory antivirals and risk to breastfeeding women

Little data is available about the ability of antiviral drugs used to treat COVID-19, coronavirus, to enter breastmilk, let alone the potential adverse effects on breastfeeding infants.

4 Mar 2020

How do cells protect themselves from viruses?

Amid the coronavirus outbreak that is wreaking havoc across the globe, it is essential to know how the cells of the body evade infection from viruses. A team of scientists has explained the mechanism that takes place in case a virus penetrates the body.

4 Mar 2020

Antibodies News and Research

Avantor launches new Protein A Chromatography Resin – PROchievA – that provides supply chain flexibility and improves downstream purification performance for monoclonal antibodies (mAbs) production

Targeting PI3Kβ alone and with combination therapy in PTEN-deficient tumors

Who should stay at home due to coronavirus?

New understanding of signaling molecule interleukin-2 can guide drug discovery efforts

Scientists use artificial intelligence to create new proteins unseen in nature

Max Planck researchers identify mechanistic basis of antigen receptor gene assembly

UK lab looks for volunteers to be infected with coronavirus

Researchers uncover possible pitfalls of common hormone analysis in animal hair

Potential breakthrough in cancer immunotherapy with gasdermin E

Novel strategy to stop tumors from developing new blood vessels

Gut bacteria can accumulate in tumors and improve effectiveness of cancer immunotherapy

Researchers develop a microfluidic chip to help detect prostate cancer

Study identifies a mutation that triggers deadly amyloidosis

Berkeley Lights Launches Cell Line Development 2.0 Workflow to Find Top Clones for Complex Antibody Therapeutics

Gene therapy reverses cardiac dysfunction in mice with Barth syndrome

Levels of sBTLA proteins may be a marker of overall survival in patients with HCC

Gut bacteria can boost effectiveness of cancer immunotherapy, mice study suggests

Sphingotec’s bio-ADM can reliably support physicians in identifying high-risk sepsis patients

Respiratory antivirals and risk to breastfeeding women

How do cells protect themselves from viruses?

Antibodies eBook

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

Latest Life Science News