Angiotensin News and Research

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Angiotensin is an oligopeptide in the blood that causes vasoconstriction, increased blood pressure, and release of aldosterone from the adrenal cortex. It is a powerful dipsogen. It is derived from the precursor molecule angiotensinogen, a serum globulin produced in the liver. It plays an important role in the renin-angiotensin system.

Covalent protein nanobodies for neutralizing SARS-CoV-2 and its variants

Researchers developed covalent nanobodies to neutralize severe acute respiratory syndrome coronavirus-2 and its variants.

18 Mar 2022

Study evaluates COVID-19 vaccination with recombinant accessory protein-deficient SARS-CoV-2

Researchers assessed the impact of recombinant accessory protein-deficient severe acute respiratory syndrome coronavirus 2 immunization against SARS-CoV-2 transmission and disease severity.

18 Mar 2022

Hypoxia-inducible factors and SARS-CoV-2 manifestations

Researchers assessed the role of hypoxia-inducible factors in SARS-CoV-2 infection, respiratory symptoms, and epithelial damage.

18 Mar 2022

Study explores SARS-CoV-2 spike epitope with potent and broad neutralization

Researchers reported an epitope with high potency and breadth and demonstrated that a therapeutic antibody directed at this site neutralizes all SARS-CoV-2 variants.

18 Mar 2022

Why does the SARS-CoV-2 Omicron variant escape immunity?

Researchers reveal the underlying mechanism associated with the Omicron variant’s increased transmissibility and ability to evade immunity.

17 Mar 2022

Study reports thiopurines inhibit the replication of the betacoronaviruses HCoV-OC43 and SARS-CoV-2

Researchers demonstrated that the thiopurines block coronaviruses spike protein assembly and integration into progeny virions.

17 Mar 2022

Narrative review reports two important mediators in SARS-CoV-2-induced ischemic stroke recovery

Researchers explored neuroinflammation and COVID-19-induced ischemic stroke recovery.

17 Mar 2022

Researchers evaluate predictors for mortality in hospitalized COVID-19 patients

Researchers identified independent factors associated with early and late deaths in hospitalized COVID-19 patients.

17 Mar 2022

Novel fusion inhibitor blocks SARS-CoV-2 spike-mediated cell-cell fusion

Researchers constructed a novel fusion inhibitor−based recombinant protein, referred to as 5−Helix, to block SARS-CoV-2 spike-mediated cell-cell fusion.

17 Mar 2022

Frail and older males more vulnerable to COVID-19 than females

Researchers evaluated the association of biological sex, frailty, and age with the vaccine-elicited immunity against SARS-CoV-2.

17 Mar 2022

In silico identification of novel curcumin derivatives as potential inhibitors against SARS-CoV-2 enzymes

Researchers identified curcumin derivatives as potential inhibitors of SARS-CoV-2 enzymes.

16 Mar 2022

Novel targets to inhibit SARS-CoV-2 variants

A new study identified additional targets on SARS-CoV-2 proteins to prevent the emergence of new SARS-CoV-2 variants of concern.

16 Mar 2022

Convalescent antibodies do not enhance SARS-CoV-2 infection

Researchers investigated whether antibodies enhance severe acute respiratory syndrome coronavirus-2 infection.

16 Mar 2022

Ethyl lauroyl arginine hydrochloride (ELAH) nasal spray as potent antiviral against SARS-CoV-2

Researchers evaluate the virucidal effects of ELAH against SARS-CoV-2 and human coronavirus-229E in a nasal spray formulation.

15 Mar 2022

SARS-CoV-2 infection model generated from human tonsil epithelial organoids

Researchers evaluate the feasibility of tonsil epithelial cell-derived organoids as an ex vivo model for studying SARS-CoV-2 infection.

15 Mar 2022

Researchers receive grant to find answers to taste loss in COVID patients

Up to 80% of individuals who've had COVID-19 report temporary or lasting changes in their sense of taste, and scientists are working to better understand the biological basis of why, including whether our taste buds are a direct virus target.

15 Mar 2022

Do anti-nucleocapsid antibodies affect COVID-19 immune reactions?

Researchers have been investigating the potential for vaccines and treatments against the nucleocapsid protein of SARS-CoV-2.

15 Mar 2022

Study evaluates efficacy of isotretinoin in improving COVID-19 outcomes

Researchers evaluated the effectiveness of isotretinoin (13-cis retinoic acid) in improving COVID-19 outcomes.

14 Mar 2022

Protection against SARS-CoV-2 Omicron variant by hetero-bivalent nanobodies

A new study investigated the broad-spectrum protection provided by hetero-bivalent nanobodies against SARS-CoV-2 variants of concern, such as Omicron.

14 Mar 2022