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Researchers study LDLR protein using new, groundbreaking techniques

Researchers from the Copenhagen Center for Glycomics at the University of Copenhagen have studied an important receptor protein called LDLR using new, groundbreaking techniques. The protein plays an important role in the absorption of the bad cholesterol, LDL.

16 Aug 2014

AEG-1 protein blocks effects of retinoic acid in leukemia and liver cancer

Retinoic acid is a form of vitamin A that is used to treat and help prevent the recurrence of a variety of cancers, but for some patients the drug is not effective.

14 Aug 2014

Even with no explicit memory of childhood trauma, PTSD can develop in adulthood

There are many forms of memory and only some of these may be critical for the development of posttraumatic stress disorder (PTSD), reports a new study by researchers at the University at Albany and the University of California Los Angeles.

14 Aug 2014

Researchers find crucial signaling pathway that helps HSCs to generate

Hematopoietic stem cells (HSCs) give rise to all other blood cell types, but their development and how their fate is determined has long remained a mystery.

14 Aug 2014

Recurrence of breast cancer cut by ½ in overweight women who regularly use NSAIDs

Recurrence of hormone-related breast cancer was cut by half in overweight and obese women who regularly used aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDs), according to data published in Cancer Research, a journal of the American Association for Cancer Research.

14 Aug 2014

Scientists identify gene that regulates sleep and wake rhythms

Scientists at the Salk Institute for Biological Studies have identified a gene that regulates sleep and wake rhythms.

14 Aug 2014

Regular exercise linked with decrease in incidence of breast cancer in African American women

Regular exercise, including brisk walking, is associated with a decrease in the incidence of breast cancer in African American women.

14 Aug 2014

Heart failure is major public health burden in many LMICs

Heart failure is a major public health burden in many low- and middle-income countries (LMICs), with substantial variation in the presentation, causes, management, and outcomes of heart failure across different LMICs, according to a study published in this week's PLOS Medicine.

From CSL Ltd 13 Aug 2014

Researchers gain rare insight into pregnancy-associated breast cancer

During pregnancy, certain hormones trigger specialized mammary stem cells to create milk-producing cells essential to lactation.

13 Aug 2014

Researchers identify mechanism used by deadly MERS virus to transmit from bats to humans

Researchers have identified the mechanism used by the deadly MERS virus to transmit from bats to humans. Bats are a native reservoir for MERS and the finding could be critical for understanding the animal origins of the virus, as well as preventing and controlling the spread of MERS and related viruses in humans.

13 Aug 2014

Blood expression levels of genes targeted by stress hormones could be biomarker for developing PTSD

Blood expression levels of genes targeted by the stress hormones called glucocorticoids could be a physical measure, or biomarker, of risk for developing Post-Traumatic Stress Disorder (PTSD), according to a study conducted in rats by researchers at the Icahn School of Medicine at Mount Sinai and published August 11 in Proceedings of the National Academy of Sciences (PNAS).

13 Aug 2014

Researchers find new ways to treat hormone receptor-positive breast cancer

A leading scientist based at Keele University in North Staffordshire has been awarded a grant of around £20,000 by research charity Breast Cancer Campaign to find new ways to treat hormone receptor-positive breast cancer, the most common type of the disease.

13 Aug 2014

Seven physicians receive ASTRO grants to advance radiation oncology research

The American Society for Radiation Oncology has selected seven leading physicians to receive a total of $675,000 in awards and grants to advance radiation oncology research. The ASTRO Junior Faculty Career Research Training Award, the ASTRO Residents/Fellows in Radiation Oncology Research Seed Grant and the ASTRO/Radiation Oncology Institute Comparative Effectiveness Research Award will fund studies in radiation and cancer biology, radiation physics, translational research, outcomes/health services research and comparative effectiveness research within radiation oncology.

12 Aug 2014

Discovery of new mechanism could lead to next generation of drugs to treat schizophrenia

Discovery of a new mechanism of drug action could lead to the next generation of drugs to treat schizophrenia.

12 Aug 2014

Mucosal lymphoid cells key to S. pneumoniae defence

Type 3 innate lymphoid cells in the lung mucosa are activated early in the course of infection with Streptococcus pneumoniae and are a major source of interleukin-22 production, research reveals.

11 Aug 2014

First-line sunitinib superior to everolimus for metastatic RCC

Results for the RECORD-3 trial support the current strategy of first-line sunitinib followed by second-line everolimus for the treatment of patients with metastatic renal cell carcinoma.

11 Aug 2014

Inovio Pharmaceuticals reports increased revenue in second quarter 2014

Inovio Pharmaceuticals, Inc. today reported financial results for the quarter ended June 30, 2014. Total revenue was $3.8 million and $6.2 million for the three and six months ended June 30, 2014, compared to $786,000 and $2.2 million for the same periods in 2013.

11 Aug 2014

Scientists identify mechanism by which inherited neurological disease causes muscle weakness in men

Researchers at University of California, San Diego School of Medicine have identified the mechanism by which a rare, inherited neurodegenerative disease causes often crippling muscle weakness in men, in addition to reduced fertility.

11 Aug 2014

Idera collaborates with TMA to advance new potential treatment approach for myositis

Idera Pharmaceuticals, Inc., a clinical stage biopharmaceutical company developing nucleic acid therapeutics for patients with cancer and rare diseases, and The Myositis Association (TMA), the only nonprofit organization dedicated to solely serving all patients with inflammatory myopathies, today announced a collaboration to advance a new potential treatment approach for polymyositis and dermatomyositis known as Toll-like receptor (TLR) antagonism.

7 Aug 2014

Soligenix demonstrates improved immunogenicity and rapid action of anthrax vaccine, VeloThrax

Soligenix, Inc., a clinical stage biopharmaceutical company focused on developing products to treat serious inflammatory diseases where there remains an unmet medical need, as well as developing several biodefense vaccines and therapeutics, announced today results demonstrating the improved immunogenicity and rapid action of its anthrax vaccine, VeloThrax™.

7 Aug 2014

Receptor News and Research

Researchers study LDLR protein using new, groundbreaking techniques

AEG-1 protein blocks effects of retinoic acid in leukemia and liver cancer

Even with no explicit memory of childhood trauma, PTSD can develop in adulthood

Researchers find crucial signaling pathway that helps HSCs to generate

Recurrence of breast cancer cut by ½ in overweight women who regularly use NSAIDs

Scientists identify gene that regulates sleep and wake rhythms

Regular exercise linked with decrease in incidence of breast cancer in African American women

Heart failure is major public health burden in many LMICs

Researchers gain rare insight into pregnancy-associated breast cancer

Researchers identify mechanism used by deadly MERS virus to transmit from bats to humans

Blood expression levels of genes targeted by stress hormones could be biomarker for developing PTSD

Researchers find new ways to treat hormone receptor-positive breast cancer

Seven physicians receive ASTRO grants to advance radiation oncology research

Discovery of new mechanism could lead to next generation of drugs to treat schizophrenia

Mucosal lymphoid cells key to S. pneumoniae defence

First-line sunitinib superior to everolimus for metastatic RCC

Inovio Pharmaceuticals reports increased revenue in second quarter 2014

Scientists identify mechanism by which inherited neurological disease causes muscle weakness in men

Idera collaborates with TMA to advance new potential treatment approach for myositis

Soligenix demonstrates improved immunogenicity and rapid action of anthrax vaccine, VeloThrax

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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