SARS CoV 2 News and Research

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Engineered decoy receptor could protect against coronaviruses

Researchers in the United States have shown that an engineered soluble decoy receptor tightly binds the spike protein of severe acute respiratory syndrome (SARS)-associated viruses. This could potentially provide protection against zoonotic betacoronaviruses such as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent responsible for the current coronavirus disease 2019 (COVID-19) pandemic.

20 Oct 2020

Precision epidemiology could help explain variability in COVID-19 symptoms

Researchers from National Taiwan University have presented a multi-omics view of how mutations in angiotensin-converting enzyme 2 (ACE2) and transmembrane protease serine 2 (TMPRSS2) affect infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and progression of coronaviruses disease 2019 (COVID-19).

20 Oct 2020

Serious ongoing symptoms in COVID-19 survivors

Although predominantly a respiratory illness, emerging data suggests that multi-organ injury is common, particularly in moderate to severe infections. A new study published on the preprint server medRxiv* in October 2020 describes the illness's sequelae in the months after recovery.

20 Oct 2020

Scientists are developing a point-of-care SARS-CoV-2 detection system based on photonic sensors

Detecting SARS-CoV-2 virus and related antibodies is essential to control the COVID-19 pandemic. A multidisciplinary team of scientists from the University of Malaga, led by Robert Halir, researcher of the Department of Communications Engineering of the Higher Technical School of Telecommunications Engineering, aware of the limitations of current techniques, are developing a point-of-care detection system based on photonic sensors.

20 Oct 2020

Highly sensitive saliva test for SARS-CoV-2 virus antigens can deliver result in under 15 minutes

Mass testing that is fast, non-invasive and able to identify cases before people show symptoms holds the key to boosting COVID-19 detection, improving contact tracing and managing disease outbreaks.

20 Oct 2020

Crystal structure of SARS-CoV-2 nucleocapsid protein RNA binding domain could guide design of antiviral agents

The outbreak of coronavirus disease (COVID-19) caused by SARS-CoV-2 virus continues to cause human infection and mortality worldwide. Currently, there are no specific viral protein-targeted therapeutics available.

20 Oct 2020

Scientists suggest that anti-malarial drugs could be repurposed to treat COVID-19

An international group of researchers believe there is enough evidence that anti-malarial drugs could be repurposed to treat COVID-19 and that they should be assessed for efficacy in clinical trials.

20 Oct 2020

Researchers develop a molecular docking based webserver to predict drug targets

A highly effective drug therapy is urgently required to combat coronavirus disease 2019 (COVID-19). The authors of this article have developed a molecular docking based webserver, namely D3Targets-2019-nCoV, with two functions, one is for predicting drug targets for drugs or active compounds observed from clinic or in vitro/in vivo studies, the other is for identifying lead compounds against potential drug targets via docking.

20 Oct 2020

Siemens Healthineers launches rapid antigen test for the detection of SARS-CoV-2

As society continues to navigate through the COVID-19 pandemic, there is a critical public health need to get ahead of the spread with a fast and simple testing for all.

From Siemens Healthineers 20 Oct 2020

Can ordinary COVID patients get the Trump treatment? It’s OK to ask

When Terry Mutter woke up with a headache and sore muscles on a recent Wednesday, the competitive weightlifter chalked it up to a hard workout.

20 Oct 2020

Fever and cough best indicators for COVID-19 in children and adolescents

Most testing is driven by fever, persistent cough of recent onset, and abnormalities in smell. Such symptoms are considered indicative of continuing SARS-CoV-2 infection, requiring quarantine of all such individuals until they test negative for the virus. This approach is justifiable in adults since fever and cough from other causes are rare in healthy adults.

20 Oct 2020

Older males who have recovered from COVID-19 are best plasma donors for treatment

Sex, age, and severity of disease may be useful in identifying COVID-19 survivors who are likely to have high levels of antibodies that can protect against the disease, according to a new study co-led by researchers at Johns Hopkins Bloomberg School of Public Health.

20 Oct 2020

Template for COVID-19 management in a rural health system

As the COVID-19 pandemic continues to challenge existing health networks, a new study published on the preprint server medRxiv in October 2020 reports on a strategy to address existing health care disparities in rural and urban areas of the USA. This should draw attention to the need for more such systems to ensure proper rural healthcare in the current and future pandemics.

20 Oct 2020

Androgen deprivation strategies could help mitigate SARS-CoV-2 infection

Since the beginning of the COVID-19 pandemic, researchers have noted that women are generally less severely affected by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This has led to the exploration into estrogen and androgens' role in the hyperinflammatory clinical phenotypes of COVID-19. A recent study published on the preprint server bioRxiv shows that drugs targeting androgens and TMPRSS2 inhibitors may potentially combat the pandemic.

20 Oct 2020

Researchers map the first draft sequence of human proteome

Twenty years after the release of the human genome, the genetic "blueprint" of human life, an international research team, including the University of British Columbia's Chris Overall, has now mapped the first draft sequence of the human proteome.

20 Oct 2020

Study shows concerning levels of COVID-19 vaccine hesitancy

More than a third of people (34%) in Turkey and one sixth of people (17%) in the UK are 'hesitant' about a COVID-19 vaccine, according to a study by UCL and Dokuz Eylul University in Turkey.

20 Oct 2020

New inhaled treatment may lead to self-administered therapy for COVID-19

An inhaled treatment against the SARS-CoV-2 virus may lead to a future self-administered therapy for COVID-19, the pandemic that has killed more than 1 million people worldwide.

20 Oct 2020

The connection between severe COVID-19 and white blood cell counts

However, in other research, white blood cells' exact roles and subtypes in severe COVID-19 are still unclear. The team writes, "It is unknown if blood cell counts before infection are associated with the risk of developing severe COVID-19." They explained that the numbers of these cell types could be influenced by several factors such as age, gender, disease status, and medications.

19 Oct 2020

Adult stem cell-based lung organoid models emulate host immune response in fatal COVID-19

Recently, a team of researchers from the University of California San Diego and The Scripps Research Institute, CA, USA, showed that an integrated stem cell-based disease modeling and computational approach is crucial for simulating the host immune response in fatal COVID-19 patients.

19 Oct 2020

Molecular simulations reveal detailed structure and dynamics of SARS-CoV-2 spike protein

Recently, researchers reported a study in which they analyzed the structure and dynamics of the spike protein using multiple molecular dynamic simulations. Their study is published on the preprint server bioRxiv.

19 Oct 2020

SARS CoV 2 News and Research

Engineered decoy receptor could protect against coronaviruses

Precision epidemiology could help explain variability in COVID-19 symptoms

Serious ongoing symptoms in COVID-19 survivors

Scientists are developing a point-of-care SARS-CoV-2 detection system based on photonic sensors

Highly sensitive saliva test for SARS-CoV-2 virus antigens can deliver result in under 15 minutes

Crystal structure of SARS-CoV-2 nucleocapsid protein RNA binding domain could guide design of antiviral agents

Scientists suggest that anti-malarial drugs could be repurposed to treat COVID-19

Researchers develop a molecular docking based webserver to predict drug targets

Siemens Healthineers launches rapid antigen test for the detection of SARS-CoV-2

Can ordinary COVID patients get the Trump treatment? It’s OK to ask

Fever and cough best indicators for COVID-19 in children and adolescents

Older males who have recovered from COVID-19 are best plasma donors for treatment

Template for COVID-19 management in a rural health system

Androgen deprivation strategies could help mitigate SARS-CoV-2 infection

Researchers map the first draft sequence of human proteome

Study shows concerning levels of COVID-19 vaccine hesitancy

New inhaled treatment may lead to self-administered therapy for COVID-19

The connection between severe COVID-19 and white blood cell counts

Adult stem cell-based lung organoid models emulate host immune response in fatal COVID-19

Molecular simulations reveal detailed structure and dynamics of SARS-CoV-2 spike protein

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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