SARS CoV 2 News and Research

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Future waves of COVID-19 will likely lead to further school closures

Researchers in the UK have warned that given how future waves of coronavirus disease 2019 (COVID-19) seem to be inevitable, it is likely that schools will be put under further pressure to close.

18 Oct 2020

Comparative analysis reveals common vulnerabilities across coronaviruses

Three lethal human respiratory syndromes associated with coronavirus (CoV) infections have emerged in the past two decades. They are severe acute respiratory syndrome (SARS) in 2002, Middle East respiratory syndrome (MERS) in 2012, and coronavirus disease 2019 (COVID-19) in 2019.

18 Oct 2020

WHO study finds Remdesivir and other repurposed drugs ineffective in COVID-19

A large-scale randomized trial has recently been conducted by the World Health Organization (WHO) to evaluate the efficacy of four repurposed antiviral medicines, including Remdesivir, Hydroxychloroquine, Lopinavir, and Interferon, currently used to treat hospitalized coronavirus disease 2019 (COVID-19) patients.

18 Oct 2020

Return to college classes tied to a 9 percent increase in COVID-19 cases, study finds

Since a vast majority of colleges and universities in the country are bringing students back for in-person instruction amid the COVID-19 pandemic, the researchers from the University of Georgia wanted to determine the effect of this return to campus on the viral case growth in countries with a significant college student population, compared to non-college countries.

18 Oct 2020

Obesity changes ACE2 and TMPRSS2 expression in mice: Implications for COVID-19

Researchers studying young obese mice found that expression of ACE2, a receptor in host cells that binds to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is higher in the lungs and trachea of obese mice. The finding could partly explain why obesity is a high-risk factor for COVID-19.

18 Oct 2020

Adhesive plastic film inactivates novel coronavirus on contact

An adhesive plastic film designed to protect surfaces such as doorknobs, handrails, elevator buttons, and touch screens inactivates the novel coronavirus on contact.

16 Oct 2020

NIH launches adaptive Phase 3 clinical trial to test immune modulator drugs in COVID-19 patients

The National Institutes of Health has launched an adaptive Phase 3 clinical trial to evaluate the safety and efficacy of three immune modulator drugs in hospitalized adults with COVID-19.

16 Oct 2020

Antibody levels drop rapidly in recovering COVID-19 patients, shows study

In the absence of approved, effective treatments for COVID-19, some hospitals have been treating patients with severe COVID symptoms with blood plasma from recovering patients.

16 Oct 2020

New diagnostic test detects and identifies SARS-CoV-2 virus in less than five minutes

Scientists from Oxford University’s Department of Physics have developed an extremely rapid diagnostic test that detects and identifies viruses in less than five minutes.

16 Oct 2020

New article explores the endemic potential of COVID-19 virus

A new article by Columbia Mailman School researchers Jeffrey Shaman and Marta Galanti explores the potential for the COVID-19 virus to become endemic, a regular feature producing recurring outbreaks in humans.

16 Oct 2020

CRISPR-based engineered cell lines can accelerate potential treatment targets for SARS-CoV-2

Synthego, the genome engineering company, has collaborated with The Krogan Lab, a world-renowned scientific research unit at the Quantitative Biosciences Institute (QBI) at the University of California, San Francisco (UCSF), to deliver multiple CRISPR-based engineered cell lines to accelerate the study of potential treatment targets for SARS-CoV-2, the novel coronavirus that causes COVID-19 disease.

16 Oct 2020

Impact of COVID-19 on Australians with hypertension

Ten months into the COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), it is unclear how people with hypertension are coping, given their increased risk. A retrospective case-control study compared people with hypertension to matched healthy controls during COVID-19 lockdown to determine whether they have higher risk perceptions, anxiety, and prevention intentions. The study is published on the preprint server medRxiv* in October 2020.

16 Oct 2020

Scientists discover a novel antiviral strategy for treating COVID-19

A research team led by Professor Hongzhe SUN, Norman & Cecilia Yip Professor in Bioinorganic Chemistry, Department of Chemistry, Faculty of Science, and Professor Kwok Yung YUEN, Henry Fok Professor in Infectious Diseases, Department of Microbiology, Li Ka Shing Faculty of Medicine of the University of Hong Kong (HKU), has discovered a novel antiviral strategy for treatment of COVID-19.

16 Oct 2020

Rapid development of functionally diverse SARS-COV-2 mouse monoclonal antibodies

Now, a recent study published on the preprint server bioRxiv in October 2020 reports the development of a rapid process for generating high-affinity mouse mAbs, and their functional attributes.

16 Oct 2020

Exposure to ancient parasites may be linked to humans’ response to coronavirus

Why are some people more resilient to viruses than others? The answer has eluded scientists for centuries and, in the age of COVID-19, has come to represent one of the holy grails of biomedical research.

16 Oct 2020

NFID issues new report detailing risks of co-infection with flu and COVID-19 in vulnerable adults

The National Foundation for Infectious Diseases (NFID) issued a new Call to Action report detailing the risks of co-infection with influenza (flu) and COVID-19 in adults with chronic health conditions, and the importance of flu vaccination during the 2020-2021 season.

16 Oct 2020

High-titer convalescent plasma reduced COVID-19 symptom severity in green monkeys

As scientists scramble to find effective vaccines and antivirals for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a recent study published on the preprint server bioRxiv in October 2020 reports that the use of convalescent plasma to treat COVID-19 disease early in the course of the illness may be among the best available strategies at present.

16 Oct 2020

Scientists reveal host pathways hijacked by three lethal coronaviruses

Seeking to inform development of drugs effective against multiple pathogenic human coronaviruses, David E. Gordon and colleagues compared host interactions of MERS-CoV, SARS-CoV-1 and SARS-CoV-2, uncovering host pathways commonly hijacked by all three.

16 Oct 2020

Sanofi Translate Bio MRT5500 COVID-19 vaccine shows promise in preclinical trials

The COVID-19 pandemic is threatening to come back in greater intensity during the winter and fall. Faced with this threat, vaccine development efforts are entering a phase of renewed focus, attempting to identify antigens capable of eliciting protective levels of neutralizing antibodies. A new study published on the preprint server bioRxiv* in October 2020 reports on a novel mRNA vaccine candidate's performance in two animal models.

16 Oct 2020

Should Australia re-open international borders?

Australian scientist Jessica Liebig from the Commonwealth Scientific and Industrial Research Organisation (CSIRO), along with fellow researchers at the Queensland University of Technology and the University of New South Wales, studied the risks involved in re-opening the international borders for travelers to Australia.

15 Oct 2020

SARS CoV 2 News and Research

Future waves of COVID-19 will likely lead to further school closures

Comparative analysis reveals common vulnerabilities across coronaviruses

WHO study finds Remdesivir and other repurposed drugs ineffective in COVID-19

Return to college classes tied to a 9 percent increase in COVID-19 cases, study finds

Obesity changes ACE2 and TMPRSS2 expression in mice: Implications for COVID-19

Adhesive plastic film inactivates novel coronavirus on contact

NIH launches adaptive Phase 3 clinical trial to test immune modulator drugs in COVID-19 patients

Antibody levels drop rapidly in recovering COVID-19 patients, shows study

New diagnostic test detects and identifies SARS-CoV-2 virus in less than five minutes

New article explores the endemic potential of COVID-19 virus

CRISPR-based engineered cell lines can accelerate potential treatment targets for SARS-CoV-2

Impact of COVID-19 on Australians with hypertension

Scientists discover a novel antiviral strategy for treating COVID-19

Rapid development of functionally diverse SARS-COV-2 mouse monoclonal antibodies

Exposure to ancient parasites may be linked to humans’ response to coronavirus

NFID issues new report detailing risks of co-infection with flu and COVID-19 in vulnerable adults

High-titer convalescent plasma reduced COVID-19 symptom severity in green monkeys

Scientists reveal host pathways hijacked by three lethal coronaviruses

Sanofi Translate Bio MRT5500 COVID-19 vaccine shows promise in preclinical trials

Should Australia re-open international borders?

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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