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New mechanism controlling transmission of abnormal signal at origin of several cancers identified

Researchers at the Institute for Research in Immunology and Cancer (IRIC) of the Universit- de Montr-al have identified a new mechanism controlling the transmission of an abnormal signal at the origin of several cancers. In an article published in the journal Cell, Marc Therrien's team explains the recent discovery of a protein complex that controls the RAS/MAPK signalling pathway, responsible for some of the deadliest cancers, including pancreatic, colon and lung cancers, and melanomas.

21 Oct 2010

Researchers identify common link among malignant tumor types in all grades of cancer

Researchers from Mount Sinai School of Medicine, in collaboration with investigators of the National Institute of Health and Medical Research (INSERM) of France led by Nicolae Ghinea, PhD, have found a common link among several malignant tumor types in all grades of cancer. This breakthrough may ultimately provide a new diagnostic or therapeutic target to detect cancer early or stop tumor growth.

21 Oct 2010

Researchers to study effect of reovirus on cancer cells

A common virus that can cause coughing and mild diarrhea appears to have a major redemptive quality: the ability to kill cancer. Harnessing that power, researchers at Georgetown Lombardi Comprehensive Cancer Center, part of Georgetown University Medical Center, are conducting a clinical trial to see if the virus can target and kill certain tumor types.

21 Oct 2010

Unitedhealth says it will test lump sum payments for some cancer care, reports earnings

Health insurer UnitedHealth said Tuesday that it will test a new way payment method for cancer doctors. The program pays doctors a lump sum payment for providing care during an entire course of care for the disease instead of how it's done now with a fee for each service a doctor provides.

21 Oct 2010

Study: p63 gene stifles spread of cancer

Long overshadowed by p53, its famous tumor-suppressing sibling, the p63 gene does the tougher, important job of stifling the spread of cancer to other organs, researchers at The University of Texas MD Anderson Cancer Center report in the Oct. 21 issue of Nature.

21 Oct 2010

A universal cancer treatment for a universal cancer marker

A latest study shows that a hormone receptor normally confined to the reproductive organs is found in malignant tumors in many parts of the body. Researchers from the Mt. Sinai School of Medicine in New York City explained that this may mean a new target for the early diagnosis and treatment of cancer. The study was published in the latest issue of The New England Journal of Medicine.

20 Oct 2010

Cipla launches generic Pirfenidone for IPF

Cipla, among the world's leading generic pharmaceutical companies, has introduced Pirfenidone in India under the brand name Pirfenex, for the treatment of IPF. A chronic progressive form of lung disease, IPF has average survival rates as low as 3-5 years which is less than many cancers. Till now there is no approved treatment for IPF.

20 Oct 2010

Aradigm reports positive data from DRCFI, ARD-3150 Phase 2b bronchiectasis study

Aradigm Corporation today announced positive top line data from its recently concluded 6-month Phase 2b study (ORBIT-2) with Aradigm's once-daily dual release ciprofloxacin for inhalation (DRCFI, ARD-3150) in patients with non-cystic fibrosis bronchiectasis.

20 Oct 2010

RWV bioreactor creates 3-D cell culture models

The cells and tissues in our bodies grow, develop and interact in a highly complex, three-dimensional world. Likewise, the various microbial pathogens that invade our bodies and cause infectious disease interact with this complex 3-D tissue milieu. In the current issue of the journal Nature Reviews Microbiology, researcher Cheryl Nickerson and her team at the Biodesign Institute at Arizona State University highlight an innovative approach for studying cells in 3-D.

20 Oct 2010

Carbon dioxide plays a role in gene regulation: Research

UCD Conway researchers have found that carbon dioxide (CO2) is not only involved in climate change and a waste product of respiration in cells but also plays an active role in regulating the genes involved in inflammation and innate immunity. Their research findings were highlighted recently in the The Journal of Immunology.

20 Oct 2010

MD Anderson treats lung cancer with pencil beam scanning proton therapy

Pencil beam scanning technology, an even more advanced and targeted form of radiation treatment known as proton therapy, is now being used to treat patients with lung cancer at The University of Texas MD Anderson Cancer Center.

20 Oct 2010

Studies explore efforts to measure, improve hospitals' surgical outcomes

Hospital Compare, an HHS website that allows patients to compare hospitals online using various indicators of quality, is intended to help them choose better facilities for their medical care. But a new report in the Archives of Surgery says the website doesn't help Medicare beneficiaries in need of certain high-risk surgeries find better facilities.

20 Oct 2010

Study reveals sex hormones can influence structure and function of heart's right ventricle

In the largest human study to date on the topic, researchers have uncovered evidence of the possible influence of human sex hormones on the structure and function of the right ventricle (RV) of the heart.

20 Oct 2010

Japanese study finds proton beam therapy safe and effective for Stage I inoperable NSCLC

Proton beam therapy is safe and effective and may be superior to other conventional treatments for Stage I inoperable non-small cell lung cancer (NSCLC) patients, according to a study in the October issue of the International Journal of Radiation Oncology•Biology•Physics, the official journal of the American Society for Radiation Oncology (ASTRO).

20 Oct 2010

NHLBI launches multicenter study of body cooling treatment in infants and children after cardiac arrest

The National Heart, Lung, and Blood Institute (NHLBI), part of the National Institutes of Health, has launched the first large-scale, multicenter study to investigate the effectiveness of body cooling treatment in infants and children who have had cardiac arrest. The Therapeutic Hypothermia after Pediatric Cardiac Arrest (THAPCA) trials total more than $21 million over six years.

20 Oct 2010

LCRF receives 2.1 million dollar donation

The largest donation in the Lung Cancer Research Foundation's history was announced in New York today by LCRF founder Laurie C. Carson.

20 Oct 2010

Jefferson researchers progress in understanding mechanism behind systemic fibrotic disorder

Scientists from the Jefferson Institute of Molecular Medicine of Thomas Jefferson University are now several steps closer to understanding the mechanism behind a novel systemic fibrotic disorder that affects some patients with renal insufficiency who receive imaging contrast agents for MRI. Two of their studies on the disorder appear together in the November issue of the Annals of Rheumatic Diseases.

20 Oct 2010

Long term exposure to air pollution increases risk of severe COPD

Long term exposure to low-level air pollution may increase the risk of severe chronic obstructive pulmonary disease (COPD), according to researcher s in Denmark. While acute exposure of several days to high level air pollution was known to be a risk factor for exacerbation in pre-existing COPD, until now there had been no studies linking long-term air pollution exposure to the development or progression of the disease.

20 Oct 2010

Researchers to study effectiveness of gamma-tocotrienol on prostate cancer cells

Survival rates of the world's most common cancer might soon be increased with a new vitamin E treatment which could significantly reduce tumour regrowth. Queensland University of Technology (QUT) prostate cancer researchers are leading the fight against a disease which kills 3000 Australian men a year.

20 Oct 2010

Forest Laboratories second quarter net sales increase 7.7% to $1,037.3 million

Forest Laboratories, Inc., an international pharmaceutical manufacturer and marketer, announced that diluted earnings per share equaled $1.00 in the second quarter of fiscal 2011.

19 Oct 2010

Lungs News and Research

New mechanism controlling transmission of abnormal signal at origin of several cancers identified

Researchers identify common link among malignant tumor types in all grades of cancer

Researchers to study effect of reovirus on cancer cells

Unitedhealth says it will test lump sum payments for some cancer care, reports earnings

Study: p63 gene stifles spread of cancer

A universal cancer treatment for a universal cancer marker

Cipla launches generic Pirfenidone for IPF

Aradigm reports positive data from DRCFI, ARD-3150 Phase 2b bronchiectasis study

RWV bioreactor creates 3-D cell culture models

Carbon dioxide plays a role in gene regulation: Research

MD Anderson treats lung cancer with pencil beam scanning proton therapy

Studies explore efforts to measure, improve hospitals' surgical outcomes

Study reveals sex hormones can influence structure and function of heart's right ventricle

Japanese study finds proton beam therapy safe and effective for Stage I inoperable NSCLC

NHLBI launches multicenter study of body cooling treatment in infants and children after cardiac arrest

LCRF receives 2.1 million dollar donation

Jefferson researchers progress in understanding mechanism behind systemic fibrotic disorder

Long term exposure to air pollution increases risk of severe COPD

Researchers to study effectiveness of gamma-tocotrienol on prostate cancer cells

Forest Laboratories second quarter net sales increase 7.7% to $1,037.3 million

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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