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STOP-BANG questionnaire on sleep apnea syndrome helps identify patients' risk for surgical complication

A research team from the Jefferson Sleep Disorders Center at Thomas Jefferson University Hospital has utilized a simple, eight-item pre-operative questionnaire about obstructive sleep apnea syndrome that could help identify patients at risk for complications following surgery, according to a report in the October issue of Archives of Otolaryngology-Head & Neck Surgery, one of the JAMA/Archives journals. Individuals prone to the obstructive sleep apnea syndrome as determined by the questionnaire appear to have an increased risk of heart, lung and other complications following elective surgery.

19 Oct 2010

Long-term use of statins reduces colorectal cancer risk

A systematic review of the medical literature supports the hypothesis that statins, cholesterol-lowering drugs used to prevent cardiac problems, are associated with reduced risk of colon and rectal cancers.

19 Oct 2010

Medifocus receives two patents to expand IP portfolio

Medifocus, Inc. is pleased to announce that it has recently received notice of allowances for two additional international patents to expand its extensive Intellectual Properties (IP) portfolio in addition to the patents Medifocus has exclusively licensed from the Massachusetts Institute of Technology (MIT).

19 Oct 2010

New LED device may help advance photodynamic therapy for skin cancer

Can skin cancer be treated with light? Scientists at the University of California, Irvine (UC Irvine), believe so. They're exploring new ways to image cancerous lesions using LEDs that might advance a technique for treating cancer called photodynamic therapy (PDT) -- work that they will describe at the Optical Society's (OSA) 94th annual meeting, Frontiers in Optics (FiO) 2010 at the Rochester Riverside Convention Center in Rochester, N.Y., from Oct. 24-28.

19 Oct 2010

New motion management software enables clear visualization of moving tumors in lung cancer

A 67-year-old female patient with lung cancer presented physicians with a difficult challenge: her tumor was small and it rode up and down with her breathing. During her treatment set up, all doctors saw on their therapy system's imaging equipment was a blur of motion. Fortunately, Leeds Teaching Hospitals NHS Trust was able to utilize its Symmetry motion management software; new imaging technology from Elekta that enables clear visualization of moving targets.

From Elekta 19 Oct 2010

Study indicates vitamin D deficiency may increase lung transplant rejection

Vitamin D deficiency is associated with a significant increase in lung transplant rejection, according to research conducted at Loyola University Health System (LUHS). These data were presented Monday at The American Society for Bone and Mineral Research 2010 annual meeting in Toronto, Ontario.

19 Oct 2010

Statins reduce risk of colon and rectal cancers: Study

A systematic review of the medical literature supports the hypothesis that statins, cholesterol‐lowering drugs used to prevent cardiac problems, are associated with reduced risk of colon and rectal cancers. A comprehensive analysis by investigators at the University of Michigan at Ann Arbor, included 22 scientific studies with more than 2.5 million combined participants.

18 Oct 2010

Vertex commences VX-770 and VX-809 combination Phase 2a clinical trial for cystic fibrosis

Vertex Pharmaceuticals Incorporated today announced the initiation of a Phase 2a clinical trial that will evaluate multiple combinations of VX-770 and VX-809, investigational oral cystic fibrosis transmembrane conductance regulator (CFTR) modulators for the treatment of cystic fibrosis (CF). The trial is designed to evaluate the safety and tolerability of VX-809 dosed alone for 14 days followed by dosing of VX-809 in combination with VX-770 for 7 days.

18 Oct 2010

Fluticasone gets rid of eosinophils in the esophagus, but does not improve symptoms

A group of Mayo Clinic researchers conducted the first controlled trial of swallowed fluticasone nasal spray (also known as Flonase) on people with the allergic esophageal condition called eosinophilic esophagitis. Research showed that the aerosolized swallowed allergy drug helped treat the cause of the throat condition, but symptoms lingered. The researchers' findings were presented today at the Annual Scientific Meeting of the American College of Gastroenterology in San Antonio.

18 Oct 2010

Study reinforces need for physicians to screen obstructive sleep apnea prior to surgery

As Americans get heavier and heavier, the incidence of obstructive sleep apnea increases, and results from two clinical studies presented at ANESTHESIOLOGY 2010 reinforce the need for physicians to screen for the disorder prior to surgery in order to appropriately manage the patient in the operating room.

18 Oct 2010

ABCs of cardiopulmonary resuscitation re-arranged

The American Heart Association is re-arranging the ABCs of cardiopulmonary resuscitation (CPR) in its 2010 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care, published in Circulation: Journal of the American Heart Association.

18 Oct 2010

Metabolon announces publication of metabolic analysis of biochemical changes in CF primary lung epithelial cells

Metabolon, Inc., the leader in global metabolomics, biomarker discovery and analysis, announces the publication of "Metabolomic Profiling Reveals Biochemical Pathways and Biomarkers Associated with Pathogenesis in Cystic Fibrosis Cells", in the Journal of Biological Chemistry.

18 Oct 2010

UK Intellectual Property Office issues patent for entinostat

Syndax Pharmaceuticals, Inc., a clinical-stage epigenetics oncology company, today announced the UK Intellectual Property Office allowed application GB0907347.9 entitled N-(2-aminophenyl)-4-[N-(pyridine-3-YL)-methoxycarbonyl-aminomethyl]-benzamide (MS-275) polymorph B.

18 Oct 2010

Discovery Labs to present lucinactant Phase 2a clinical study results at NACFC Conference

Discovery Laboratories, Inc. today announces that the Phase 2a clinical study of aerosolized KL4 surfactant (lucinactant) in patients with cystic fibrosis (CF) has completed and the results from the study will be presented at the upcoming North American Cystic Fibrosis Conference (NACFC; October 21-23, 2010).

15 Oct 2010

New development of genetic tool to speed discovery of novel genes involved in cancer

Researchers have developed a genetic tool in mice to speed the discovery of novel genes involved in cancer. The system - called PiggyBac - has already been used by the team to identify novel candidate cancer-causing genes.

15 Oct 2010

Journal of Clinical Oncology publishes IPI-504 Phase 2 study results

Infinity Pharmaceuticals, Inc. announced that results from its Phase 2 study of IPI-504, a novel IV-administered Hsp90 chaperone inhibitor, in patients with advanced non-small cell lung cancer (NSCLC) were published in the Journal of Clinical Oncology.

15 Oct 2010

FibroGen announces initiation of FG-3019 phase 2 study for reversing liver fibrosis

FibroGen, Inc. today announced initiation of a phase 2 study to compare the efficacy of FG-3019, a human monoclonal antibody against connective tissue growth factor (CTGF), with placebo in reversing liver fibrosis (scarring of the liver) due to chronic infection with hepatitis B virus (HBV).

15 Oct 2010

BIOTRONIK announces European release of TI Trend Chart

BIOTRONIK SE Co. & KG, leading manufacturer of cardiovascular devices, has announced the European release of its Thoracic Impedance (TI) Trend Chart via its pioneering BIOTRONIK Home Monitoring technology and Lumax 540 implantable cardiac defibrillator (ICD) series.

15 Oct 2010

Cancer cluster among Sydney Harbour Bridge workers triggers investigation

There are reports of a cancer cluster among Sydney Harbour Bridge workers with at least eight known cases that unions believe are linked to the use of lead paint. The Roads and Traffic Authority (RTA) will investigate the matter. Of the eight workers five have already died and all of them had been involved in painting and maintaining the bridge for more than 10 years, the Construction Forestry Mining and Energy Union (CFMEU) said. This included scraping off lead paint, initially with little protective equipment.

14 Oct 2010

28% of health care workers in 'work risk' category will not get flu vaccine

A new Consumer Reports Health poll reveals a disconcerting proportion of "at risk" groups who will not get the flu vaccine this year. Of most concern, only 40% of Americans in the "work risk" category—meaning those who care for young children and those who work in residential nursing homes, hospitals, and other health care environments—said they would definitely get the vaccine this year, which combines the seasonal and the 2009 H1N1 (swine) flus, while 28% said they would definitely not get the vaccine.

14 Oct 2010

Lungs News and Research

STOP-BANG questionnaire on sleep apnea syndrome helps identify patients' risk for surgical complication

Long-term use of statins reduces colorectal cancer risk

Medifocus receives two patents to expand IP portfolio

New LED device may help advance photodynamic therapy for skin cancer

New motion management software enables clear visualization of moving tumors in lung cancer

Study indicates vitamin D deficiency may increase lung transplant rejection

Statins reduce risk of colon and rectal cancers: Study

Vertex commences VX-770 and VX-809 combination Phase 2a clinical trial for cystic fibrosis

Fluticasone gets rid of eosinophils in the esophagus, but does not improve symptoms

Study reinforces need for physicians to screen obstructive sleep apnea prior to surgery

ABCs of cardiopulmonary resuscitation re-arranged

Metabolon announces publication of metabolic analysis of biochemical changes in CF primary lung epithelial cells

UK Intellectual Property Office issues patent for entinostat

Discovery Labs to present lucinactant Phase 2a clinical study results at NACFC Conference

New development of genetic tool to speed discovery of novel genes involved in cancer

Journal of Clinical Oncology publishes IPI-504 Phase 2 study results

FibroGen announces initiation of FG-3019 phase 2 study for reversing liver fibrosis

BIOTRONIK announces European release of TI Trend Chart

Cancer cluster among Sydney Harbour Bridge workers triggers investigation

28% of health care workers in 'work risk' category will not get flu vaccine

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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