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Using computer simulations to examine personalized mechanical ventilation of COVID-19 patients

Initial clinical guidelines for mechanical ventilation of COVID-19 patients suggested following standard approaches used in the treatment of acute respiratory distress syndrome (ARDS), which is characterized by rapid onset of widespread inflammation in the lungs.

21 Sep 2020

Study finds wide variation in levels and anti-tumor effectiveness of a common cancer drug

When used to manage infections, the drug itraconazole is generally given at a single, fixed dose to all patients.

17 Sep 2020

Virtual screening tool simplifies the process of diagnosing pulmonary hypertension

The COVID-19 pandemic has increasing numbers of doctors caring for patients virtually. While critical to protecting patient health during a pandemic, however, virtual care presents unique challenges, especially when it comes to diagnosis.

17 Sep 2020

COVID-19 could be diagnosed using stroke scans

New research from King's College London has found that COVID-19 may be diagnosed on the same emergency scans intended to diagnose stroke.

17 Sep 2020

Researchers develop 3D functional heart organoids from mouse embryonic stem cells

Heart development as it happens in vivo, or in a living organism, is a complex process that has traditionally been difficult to mimic in vitro, or in the laboratory.

16 Sep 2020

Conditions linked to obesity leave the lungs of obese patients more susceptible to COVID-19

Conditions related to obesity, including inflammation and leaky gut, leave the lungs of obese patients more susceptible to COVID-19 and may explain why they are more likely to die from the disease, UTSW scientists say in a new article published online in eLife.

16 Sep 2020

Researchers and clinicians share findings on ovarian cancer

After nearly four years of work, a group of researchers and clinicians from the University of Colorado (CU) published a paper this week in the Clinical Cancer Research that shares findings from research looking at how the composition of ovarian cancer tumors changes during chemotherapy and contributes to therapeutic response.

16 Sep 2020

Blood pressure control has worsened in the U.S.

A new study has revealed that uncontrolled blood pressure among Americans is on the rise compared to a few years back. The study by the researchers from the University of Alabama was published this week on the JAMA Network.

16 Sep 2020

COVID-19 works with the body's microbiota to increase disease severity in obese and diabetic patients

The combined effects of the body's microbiota working together with COVID-19 in the lungs could explain the severity of the disease in people with obesity and diabetes, according to a new article published today in eLife.

15 Sep 2020

3D cluster of cells could enhance myocardial repair

Cell therapy for cardiac regeneration, while promising, has been hampered by issues with long-term survival of the transplanted cells.

15 Sep 2020

RNA nanoparticles show great promise for targeted delivery of anticancer drugs

A new study by researchers at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC - James) shows that RNA nanoparticles have elastic and rubbery properties that help explain why these particles target tumors so efficiently and why they possess lower toxicity in animal studies.

15 Sep 2020

Researchers detect significant amounts of DNA traps in lungs of deceased Covid-19 patients

A multidisciplinary team of researchers from the University of Liège (Belgium) has detected significant amounts of DNA traps in distinct compartments of the lungs of patients who died from Covid-19.

15 Sep 2020

Phosphate binder drug does not reduce heart disease risk in people with chronic kidney disease

Following a large-scale clinical trial, researchers have found that lanthanum carbonate does not reduce the risk of cardiovascular disease developing in patients with chronic kidney disease.

14 Sep 2020

Sticky DNA webs may cause tissue damage associated with severe COVID-19 infections

Sticky webs of DNA released from immune cells known as neutrophils may cause much of the tissue damage associated with severe COVID-19 infections, according to two new studies published September 14 in the Journal of Experimental Medicine.

14 Sep 2020

Parkinson's disease drug may improve vision in patients with age-related macular degeneration

Investigators have determined that treating patients with an advanced form of age-related macular degeneration (AMD) with levodopa, a safe and readily available drug commonly used to treat Parkinson's disease, stabilized and improved their vision.

10 Sep 2020

Intestinal grafts grown using stem cells could lead to personalized transplants for children

Pioneering scientists at the Francis Crick Institute, Great Ormond Street Hospital and UCL Great Ormond Street Institute of Child Health have grown human intestinal grafts using stem cells from patient tissue that could one day lead to personalized transplants for children with intestinal failure, according to a study published in Nature Medicine today (Monday 7th September).

10 Sep 2020

Protein aggregation reduces elasticity of blood vessels in the brain

Deposits of a protein called "Medin", which manifest in virtually all older adults, reduce the elasticity of blood vessels during aging and hence may be a risk factor for vascular dementia.

9 Sep 2020

Study reveals complex immunology behind MIS-C in children with COVID-19

In a recent paper published in the prestigious journal Cell, researchers from Sweden and Italy show that inflammatory response in Multisystem Inflammatory Syndrome in Children associated with coronavirus disease (COVID-19) differs from the cytokine storm found in severe acute illness, involving autoantibodies at the same time and sharing several features with Kawasaki disease.

8 Sep 2020

Lack of oxygen can trigger tumor metastases

Metastases are formed by cancer cells that break away from the primary tumor. A research group at the University of Basel has now identified lack of oxygen as the trigger for this process.

8 Sep 2020

Fight for Sight partners with Diabetes UK to investigate link between eye disease and COVID-19

Eye research charity Fight for Sight is partnering with Diabetes UK to investigate if people with the eye disease diabetic retinopathy are at greater risk of developing complications from Covid-19, in a study that hopes to save lives.

8 Sep 2020

Blood Vessels News and Research

Using computer simulations to examine personalized mechanical ventilation of COVID-19 patients

Study finds wide variation in levels and anti-tumor effectiveness of a common cancer drug

Virtual screening tool simplifies the process of diagnosing pulmonary hypertension

COVID-19 could be diagnosed using stroke scans

Researchers develop 3D functional heart organoids from mouse embryonic stem cells

Conditions linked to obesity leave the lungs of obese patients more susceptible to COVID-19

Researchers and clinicians share findings on ovarian cancer

Blood pressure control has worsened in the U.S.

COVID-19 works with the body's microbiota to increase disease severity in obese and diabetic patients

3D cluster of cells could enhance myocardial repair

RNA nanoparticles show great promise for targeted delivery of anticancer drugs

Researchers detect significant amounts of DNA traps in lungs of deceased Covid-19 patients

Phosphate binder drug does not reduce heart disease risk in people with chronic kidney disease

Sticky DNA webs may cause tissue damage associated with severe COVID-19 infections

Parkinson's disease drug may improve vision in patients with age-related macular degeneration

Intestinal grafts grown using stem cells could lead to personalized transplants for children

Protein aggregation reduces elasticity of blood vessels in the brain

Study reveals complex immunology behind MIS-C in children with COVID-19

Lack of oxygen can trigger tumor metastases

Fight for Sight partners with Diabetes UK to investigate link between eye disease and COVID-19

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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