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American PhRMA companies commit $25M in medicines, medical supplies and cash for Haiti relief efforts

As the need for health care assistance mounts after the recent catastrophic earthquake in Haiti, America's pharmaceutical research and biotechnology companies continue to provide help. So far, more than $25 million in medicines, medical supplies and cash have been committed to relief efforts – and that amount is still growing. The total does not include the contributions of PhRMA member company employees and the many companies committed to matching the pledges of their workers.

30 Jan 2010

Research roundup: Raising seniors' co-pays increases costs; The stimulus and safety net providers

New England Journal of Medicine: Increased Ambulatory Care Copayments And Hospitalizations Among The Elderly - This study examines the consequences of increasing copayments for outpatient care of Medicare enrollees in managed-care plans. "As compared with matched control plans in which copayments for ambulatory care were unchanged, Medicare plans that increased these copayments by an average of 95% for primary care and 74% for specialty care had a reduction in the number of outpatient visits but an increase in hospital admissions, in the number of days of hospital care, and in the proportion of enrollees who used hospital care," the authors write.

30 Jan 2010

New biomarker may predict treatment outcomes in RA patients

Investigators have identified a biomarker that could help doctors select patients with rheumatoid arthritis who will benefit from therapy with drugs such as Enbrel, a tumor necrosis factor (TNF)-antagonist drug.

30 Jan 2010

Aurora St. Luke's Medical Center honored with HealthGrades' Distinguished Hospital Award for Clinical Excellence

Aurora St. Luke's Medical Center has been identified by HealthGrades as a 2010 recipient of the Distinguished Hospital Award for Clinical Excellence. HealthGrades awards this title to facilities that rank in the top five percent in overall clinical performance.

30 Jan 2010

FDA approves new drug combination for hormone positive and HER2-positive advanced breast cancer

The U.S. Food and Drug Administration today approved Tykerb (lapatinib) in combination with Femara (letrozole) to treat hormone positive and HER2-positive advanced breast cancer in postmenopausal women for whom hormonal therapy is indicated.

30 Jan 2010

Docking algorithm EADock allows successful design of new inhibitors for anti-cancer target

Many human tumors express indoleamine 2,3-dioxygenase (IDO), an enzyme which mediates an immune-escape in several cancer types. Researchers in the Molecular Modeling group at the SIB Swiss Institute of Bioinformatics and Dr. Beno-t J. Van den Eynde's group at the Ludwig Institute for Cancer Research Ltd (LICR) Brussels Branch developed an approach for creating new IDO inhibitors by computer-assisted structure-based drug design. The study was presented in the January 2010 online issue of the Journal of Medicinal Chemistry.

30 Jan 2010

New study identifies that SynDIG1 plays critical role in creating and sustaining synapses

A new study from UC Davis Health System identifies for the first time a brain protein called SynDIG1 that plays a critical role in creating and sustaining synapses, the complex chemical signaling system responsible for communication between neurons.

30 Jan 2010

Rubicon Genomics reaches agreement with ZyGEM to market its PicoPlex single-cell amplification kits

Rubicon Genomics, Inc., a developer of pre-analytical amplification products that enable more comprehensive genetic analysis of clinical and research samples, announced today that it has reached agreement with ZyGEM to non-exclusively market Rubicon's PicoPlex™ single-cell amplification kits in Australia and New Zealand.

30 Jan 2010

$Study shows hip fractures in elderly men are linked to impaired bone health in their grandsons$

Study shows hip fractures in elderly men are linked to impaired bone health in their grandsons

If your grandfather has had a hip fracture, you too could be at risk. Researchers at the Sahlgrenska Academy at the University of Gothenburg, Sweden, have been able to show, for the first time, a link between hip fractures in elderly men and impaired bone health in their grandsons.

30 Jan 2010

Study shows majority of patients gain weight after knee replacement surgery

You'd think folks who've had knee replacement surgery -- finally able to walk and exercise without pain -- would lose weight instead of put on pounds, but surprisingly that's not the case, according to a University of Delaware study.

30 Jan 2010

$Perifosine holds promise as a single agent for relapsed/refractory Waldenstrom's Macroglobulinemia$

Perifosine holds promise as a single agent for relapsed/refractory Waldenstrom's Macroglobulinemia

Æterna Zentaris Inc., a late-stage drug development company specialized in oncology and endocrinology, today announced that an article entitled "Clinical and Translational Studies of a Phase II Trial of the Novel Oral Akt Inhibitor Perifosine in Relapsed or Relapsed/Refractory Waldenstrom's Macroglobulinemia," reporting Phase 2 data demonstrating the single agent activity of perifosine (KRX-0401) for the treatment of advanced Waldenstrom's Macroglobulinemia ("Waldenstrom's"), will appear in the February 1, 2010 issue of the Journal of Clinical Cancer Research.

30 Jan 2010

Joslin.org and dLife.com announce new online partnership

Joslin.org, the Internet site for Harvard-affiliated Joslin Diabetes Center, the world's preeminent diabetes research and clinical care organization, and dLife.com, the leading online community for people living with diabetes, today announced a new online partnership.

29 Jan 2010

Diffusion Pharmaceuticals closes on $5.9M in additional private financing

Diffusion Pharmaceuticals LLC, a clinical-stage drug-development company commercializing first-in-class drugs to treat serious or life-threatening unmet medical conditions, today announced that it closed on $5.9 million in additional private financing during the second half of 2009, bringing the total the company raised in 2009 to $7.1 million.

29 Jan 2010

Positive Phase 2 trial results of Keryx Biopharmaceuticals' KRX-0401 announced

Keryx Biopharmaceuticals, Inc. (the "Company") today announced that an article entitled "Clinical and Translational Studies of a Phase II Trial of the Novel Oral Akt Inhibitor Perifosine in Relapsed or Relapsed/Refractory Waldenstrom's Macroglobulinemia," reporting Phase 2 data demonstrating the single agent activity of KRX-0401 (Perifosine) for the treatment of advanced Waldenstrom's Macroglobulinemia ("Waldenstrom's"), will appear in the February 1, 2010 issue of Clinical Cancer Research.

29 Jan 2010

Recent releases in Global Health

Rajiv Shah's appointment as USAID administrator "comes at a crucial time of challenge and opportunity for the Agency to improve the nutritional well-being of impoverished societies," write the authors of a Lancet Comment that examines the U.S. Global Hunger and Food Security Initiative. Though the initiative "sends a clear message to the world about U.S. intent to partner with poor nations to achieve their national food and nutrition goals … the Initiative's nutrition plan, unlike its detailed agricultural blueprint, currently lacks a comprehensive set of aims, activities, research needs, and programme benchmarks," the authors write.

29 Jan 2010

New mathematical model helps in predicting treatment outcomes for cervical cancer patients

Cervical cancer is highly curable when caught early. But in a third of cases, the tumor responds poorly to therapy or recurs later, when cure is much less likely.

29 Jan 2010

ConjuChem Biotechnologies reports financial results for fiscal year ended October 31, 2009

The Company's net loss for the quarter ended October 31, 2009 amounted to $2.5 million or ($0.01) per share, compared to $10.9 million or ($0.04) per share, for the quarter ended October 31, 2008.

29 Jan 2010

Agent-enhanced CT scan plays a supporting role in diagnosing severe cases of H1N1 flu virus

Published reports on the usefulness of CT scans for complicated H1N1 cases have spurred use of these procedures in U.S. hospitals. According to healthcare market research publisher Kalorama Information, this opens up a pathway of diagnostics for physicians and overall is a positive sign not only for the technology but also for companies making chemical agents for procedures.

29 Jan 2010

IDEXX Laboratories reports revenues for fourth-quarter of 2009

IDEXX Laboratories, Inc., today reported that revenues for the fourth quarter of 2009 increased 11% to $270.3 million, from $243.3 million for the fourth quarter of 2008.

29 Jan 2010

Quantrx Biomedical signs agreement to acquire NuRx Pharmaceuticals

QuantRx Biomedical Corporation today announced that it has entered into an agreement to acquire NuRx Pharmaceuticals, Inc. (OTCBB: NUXP). The transaction is structured as a tax-free, all stock acquisition resulting in a combined company with no debt and a simplified ownership and capital structure.

29 Jan 2010

Research News and Research

American PhRMA companies commit $25M in medicines, medical supplies and cash for Haiti relief efforts

Research roundup: Raising seniors' co-pays increases costs; The stimulus and safety net providers

New biomarker may predict treatment outcomes in RA patients

Aurora St. Luke's Medical Center honored with HealthGrades' Distinguished Hospital Award for Clinical Excellence

FDA approves new drug combination for hormone positive and HER2-positive advanced breast cancer

Docking algorithm EADock allows successful design of new inhibitors for anti-cancer target

New study identifies that SynDIG1 plays critical role in creating and sustaining synapses

Rubicon Genomics reaches agreement with ZyGEM to market its PicoPlex single-cell amplification kits

Study shows hip fractures in elderly men are linked to impaired bone health in their grandsons

Study shows majority of patients gain weight after knee replacement surgery

Perifosine holds promise as a single agent for relapsed/refractory Waldenstrom's Macroglobulinemia

Joslin.org and dLife.com announce new online partnership

Diffusion Pharmaceuticals closes on $5.9M in additional private financing

Positive Phase 2 trial results of Keryx Biopharmaceuticals' KRX-0401 announced

Recent releases in Global Health

New mathematical model helps in predicting treatment outcomes for cervical cancer patients

ConjuChem Biotechnologies reports financial results for fiscal year ended October 31, 2009

Agent-enhanced CT scan plays a supporting role in diagnosing severe cases of H1N1 flu virus

IDEXX Laboratories reports revenues for fourth-quarter of 2009

Quantrx Biomedical signs agreement to acquire NuRx Pharmaceuticals

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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