What are step gradients, and how to use them?

	Analytical Chemistry in Life Sciences
	The latest analytical chemistry news from AZoLifeSciences

Linear gradients, characterized by a constant change in mobile phase composition over time, are commonly employed in chromatography. But when they are not enough, step gradients, or focused gradients, can save the day. Discover how to use them more efficiently.

Learn How to Use Step Gradients

			Study links endocrine-disrupting chemical exposure to poorer sleep and vitamin D deficiency Study in the journal Nutrients links exposure to endocrine-disrupting chemicals with vitamin D deficiency and reduced sleep duration, suggesting a compounded negative impact on health.

			Study finds high microplastic levels in Mediterranean fish despite low chemical contaminants Researchers in a recent study published in the journal Foods discovered high levels of microplastics in popular Mediterranean fish species, despite low levels of cadmium and antibiotics, highlighting ongoing environmental concerns.

	New technique allows scientists to study the fatty contents of cancer cells Imagine being able to look inside a single cancer cell and see how it communicates with its neighbors.

	The Incredible Impact of Mass Spectrometry on Brain Imaging Researchers Jonathan Sweedler, a professor of chemistry, and Fan Lam, a professor of bioengineering, at the Beckman Institute for Advanced Science and Technology, described how spatial omics technologies can unveil the molecular complexity of the brain at various scales.

	What Methods Are Used in Beverage Contaminant Analysis? Contaminants in beverages in the form of chemicals, particulates, or microorganisms may be naturally sourced from the environment or through anthropogenic activities.

	MALDI-TOF Mass Spectrometry in the Biosciences Matrix-assisted laser desorption/ionization (MALDI) time-of-flight (TOF) spectrometry is a powerful analytical technique that is widely used in both clinical and laboratory settings.

	Revolutionising Biomarker Discovery: The Role of High-Performance Liquid Chromatography Methods to identify new biomarkers and detect existing ones with high specificity and selectivity are greatly needed.

	New Method Sheds Light on How Protein Modifications Power T Cells Imagine riding a bike. Now imagine riding a bike with an enormous beach ball stuck on your handlebars. That "modification" might change your experience quite a bit.

	Exhaled breath may be a promising avenue for antibiotic monitoring Exhaled breath may be very promising alternative to blood for the therapeutic monitoring of antibiotics, the ESCMID Global Congress (formerly ECCMID) in Barcelona, Spain (27-30 April) will hear.

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