Eating oranges daily may shift lipid patterns in fatty liver disease
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 Low-plastic diets cut plastic-linked chemicals in urine within 7 days, study findsLow-plastic diets cut plastic-linked chemicals in urine within 7 days, study finds
 
A Nature Medicine study found that healthy Australian adults were widely exposed to plastic-associated chemicals, with processed, packaged, and canned foods emerging as important modifiable contributors to urinary phthalate and bisphenol levels. In a 7-day pilot randomized trial, low-plastic food interventions reduced several urinary plastic-associated chemicals without lowering daily energy intake.
 
 
 Eating oranges daily may shift lipid patterns in fatty liver diseaseEating oranges daily may shift lipid patterns in fatty liver disease
 
A 4-week trial on 'Navelina' oranges shows potential effects on lipid metabolism in fatty liver disease, revealing intriguing but non-significant patterns.
 
   Obesity, GLP-1s, and metabolic careObesity, GLP-1s, and metabolic care
 
An interview with Professor Thomas Forst, Chief Medical Officer, hVIVO
 
   What are the best alternatives to opioids for chronic pain reliefWhat are the best alternatives to opioids for chronic pain relief
 
This article examines emerging non-opioid strategies for chronic pain, from targeted ion-channel drugs and anti-inflammatory biologics to neuromodulation, behavioral therapies, and digital pain tools. It highlights how precision, multimodal care may improve pain control while reducing reliance on opioids.
 
   Scientists discover BRCA links to head and neck cancer risksScientists discover BRCA links to head and neck cancer risks
 
An international group led by researchers from the RIKEN Center for Integrative Medical Sciences (IMS) in Japan have discovered associations between pathogenic variants of the BRCA 1 and 2 genes and four types of cancer. Published in ESMO Open, the findings expand the potential for personalized medicine to several cancer types that currently have limited treatment options and poor prognoses.
 
 NHS grant funds study on the use of weight-loss drugs for treating PCOS
 
NHS grant funds study on the use of weight-loss drugs for treating PCOSDr. Shagaf Bakour, a gynecologist and director of medical education at Aston Medical School, has won an NHS research grant to investigate the use of weight-loss drugs in the treatment of polycystic ovary syndrome (PCOS).
 
 
 Higher stress and BMI tied to earlier puberty in girls
 
Higher stress and BMI tied to earlier puberty in girlsNew research links stress, BMI, and hormone patterns to pubertal timing, revealing implications for long-term health and early intervention strategies.
 
 
 As US birth rate falls, feds’ response may make pregnancy more dangerous
 
As US birth rate falls, feds’ response may make pregnancy more dangerousThe number of babies born in the United States fell again last year.
 
 
 Clinical barriers prevent hormone therapy access after cervical cancer treatment
 
Clinical barriers prevent hormone therapy access after cervical cancer treatmentMost oncologists say they would prescribe hormone therapy to cervical cancer patients who experience early menopause from radiation treatment, but barriers are keeping many from doing so in practice, according to a new University of Kentucky Markey Cancer Center study published in JAMA Network Open.
 
 
 High-fat, low-carbohydrate diet may improve beta-cell function in patients with type 2 diabetes
 
High-fat, low-carbohydrate diet may improve beta-cell function in patients with type 2 diabetesPeople with type 2 diabetes on a high-fat, low-carbohydrate diet may have a better chance of reversing their diabetes than those on a low-fat diet, according to a small study published in the Journal of the Endocrine Society.
 
 
 Understanding periostin as a biomarker in allergic diseases
 
Understanding periostin as a biomarker in allergic diseasesEvidence highlights periostin as a useful indicator of immune response, supporting research and clinical evaluation of allergic conditions.
 
 
 Serotonin may worsen tinnitus symptoms, mice study finds
 
Serotonin may worsen tinnitus symptoms, mice study findsThe same neurotransmitter commonly leveraged to relieve symptoms of depression and anxiety also may exacerbate a vexing condition known as tinnitus, according to new research published in the Proceedings of the National Academy of Sciences.
 
 
 Researchers use tiny glass capillaries to sample living cancer cell parts
 
Researchers use tiny glass capillaries to sample living cancer cell partsA new analytical method could improve how cancer treatments are designed - by allowing scientists to track, for the first time, exactly where inside a living cell a drug accumulates. Researchers from the University of Surrey and King's College London developed the method, which detects trace amounts of metal inside individual living cells and their internal compartments without the need to kill the cells first
 
 
 Three essential biomarkers for measuring immune activation
 
Three essential biomarkers for measuring immune activationAccurate measurement of HMGB-1, neopterin and sIL-2R supports reliable assessment of immune activation across clinical and research applications.
 
 
 Why do the deadliest cancers still get less NIH research funding?
 
Why do the deadliest cancers still get less NIH research funding?Researchers found that NIH funding for major US cancers does not consistently align with lethality, with highly fatal cancers such as pancreatic cancer and small-cell lung cancer receiving far less funding per estimated death than breast or prostate cancer. The study argues that incidence alone is not enough and that funding decisions should better incorporate mortality, survival, and mortality-to-incidence ratios.
 
 
 Researchers use light-activated drugs to map the brain's internal painkillers
 
Researchers use light-activated drugs to map the brain's internal painkillersPlacebo effects, in which patients experience relief without therapeutic treatment, increasingly have been considered as potentially powerful clinical treatments for ailments such as depression and pain. Yet the neurological mechanisms underlying such processes are not fully understood.
 
 
 An Arm and a Leg: The accidental architect of America’s drug patent problem
 
An Arm and a Leg: The accidental architect of America’s drug patent problemDepending on whom you ask, Alfred Engelberg could be a hero or a villain in the story of American pharmaceuticals.
 
 
 Brain organoids may guide Alzheimer’s diagnosis and treatment
 
Brain organoids may guide Alzheimer’s diagnosis and treatmentScientists from Johns Hopkins Medicine report new evidence that clusters of brain tissue derived from the cells of patients with Alzheimer's disease may be used to evaluate how certain patients with the neurodegenerative condition may respond to drugs commonly prescribed to treat psychiatric symptoms of the disorder.
 
 
 Prediabetes leaves lasting fat tissue changes after bariatric surgery
 
Prediabetes leaves lasting fat tissue changes after bariatric surgeryPrediabetes may leave a lasting molecular "footprint" on adipose (fat) tissue which appears to make maintaining weight loss after bariatric surgery more difficult, according to new research being presented at this year's European Congress on Obesity (ECO) in Istanbul, Turkey (12-15 May).
 
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