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The latest endocrinology news from News Medical |
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 | | |  When you eat matters: early time-restricted eating improves metabolic health Time-restricted eating improves several metabolic outcomes compared with usual diets, with benefits observed for body weight, adiposity, blood pressure, insulin, glucose, and triglycerides. Early eating windows consistently outperform late eating, while the optimal duration of food intake remains uncertain. | | | | |  Gut problems may shape Parkinson’s disease progression through the gut-brain axis This narrative review examines how gastrointestinal dysfunction, gut dysbiosis, and altered gut-brain axis signaling are closely associated with the onset and progression of Parkinson’s disease. It synthesizes evidence supporting a possible bottom-up disease model while highlighting integrative, gut-targeted strategies as adjuncts to symptom management rather than proven disease-modifying therapies. | |
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| | | | |  A new study led by Mayo Clinic found that postmenopausal women receiving menopausal hormone therapy lost 35% more weight while taking tirzepatide, a Food and Drug Administration-approved drug for the treatment of overweight and obesity. | | | | |  The cancer gene MYC camouflages tumors by suppressing alarm signals that normally activate the immune system. | | | | |  Edible cacti, especially Opuntia cladodes, show consistent short-term benefits for postprandial blood glucose and modest improvements in lipid biomarkers, largely driven by soluble fiber and bioactive compounds. Human evidence for gut microbiota modulation and long-term cardiometabolic outcomes remains preliminary, supporting cactus as a complementary dietary strategy rather than a therapeutic intervention. | | | | |  A new preclinical study from researchers at The University of Texas MD Anderson Cancer Center, published today in Nature Communications, identifies a powerful strategy to overcome drug resistance in breast cancer by simultaneously targeting two key cell-cycle regulators, CDK2 and CDK4/6. | | | | |  A deep dive into the scientific shift toward multi-target obesity therapeutics and its implications for metabolic health and disease prevention. | | | | |  A routine creatinine blood test may identify individuals at higher risk for osteoporosis and fractures, highlighting its potential as a risk assessment tool. | | | | |  This study shows that specific ratios of circulating sphingolipids to steroids can predict the risk of future asthma exacerbations over five years with high discriminatory performance. By integrating metabolomics with longitudinal medical records, the research highlights lipid–hormone pathway imbalance as a key driver of asthma instability. | | | | | Could this mark a shift in how we think about cancer therapy? At least in the laboratory, evidence suggests it may be. | | | | |  City of Hope, one of the largest and most advanced cancer research and treatment organizations in the United States with its National Medical Center ranked among the nation's top cancer centers by U.S. News & World Report, has opened a phase 2 clinical trial comparing three different strategies for protecting heart health in prostate cancer patients who receive androgen deprivation therapy (ADT), a potentially lifesaving hormone therapy. | | | | |  A new study led by Aaron Hobbs, Ph.D., and Rachel Burge, Ph.D., at MUSC Hollings Cancer Center, reveals why a specific gene mutation behaves differently from other variants. | | | | |  People with type 2 diabetes face a higher risk of heart attacks, strokes and other cardiovascular problems, according to the National Institutes of Health. | | | | |  Insulin use in gestational diabetes presents challenges; education and support are key to overcoming fears and ensuring effective self-management for mothers. | | | | | The second annual report from the National Cancer Database (NCDB) of the American College of Surgeons (ACS) documents a substantial rise in medication treatments, such as chemotherapy, immunotherapy, and hormone therapy, used before surgery to treat many cancers, often allowing less invasive surgery and helping clinicians assess how a patient's cancer responds to medication to guide the most effective treatment options. | | | | |  A landmark UK study involving tens of thousands of families has shown that childhood screening for type 1 diabetes is effective, laying the groundwork for a UK-wide childhood screening program. | | | | |  Researchers have identified a protein pattern that, already at birth, looks markedly different in those who later go on to develop type 1 diabetes. The findings show that a combination of several factors during pregnancy increases the risk of the child later developing the disease. The study is published in Nature Communications and was led by researchers at Linköping University, Sweden, and the University of Florida, USA. | |
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