Study links semaglutide and tirzepatide to fewer anxiety and depression diagnoses in obesity care
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 Gut microbiota may shape eating behavior and guide new obesity treatmentsGut microbiota may shape eating behavior and guide new obesity treatments
 
The review shows how gut microbiota may influence appetite, food reward, inflammation, and energy balance through the gut-brain axis. Microbiota-targeted approaches could support future treatments for obesity and eating disorders, but clinical evidence remains limited.
 
 
 Study links semaglutide and tirzepatide to fewer anxiety and depression diagnoses in obesity careStudy links semaglutide and tirzepatide to fewer anxiety and depression diagnoses in obesity care
 
A US electronic health record study found that adults with obesity who started semaglutide or tirzepatide had lower recorded hazards of anxiety and depression than matched patients using naltrexone-bupropion. However, among adults without type 2 diabetes, tirzepatide was linked to higher recorded hazards of anxiety and insomnia than semaglutide, underscoring the need for cautious monitoring.
 
   Study links GLP-1 treatment to fewer alcohol drinking daysStudy links GLP-1 treatment to fewer alcohol drinking days
 
Current GLP-1 receptor agonist prescriptions were associated with modestly lower AUDIT-C scores in a large, diverse US cohort. The difference appeared to reflect less frequent drinking rather than fewer drinks per occasion or fewer binge-drinking episodes.
 
   Biohub researchers use artificial intelligence to uncover new psoriasis targetsBiohub researchers use artificial intelligence to uncover new psoriasis targets
 
Biohub researchers performed what they believe is the first genome-wide CRISPR study of primary human adult skin cells, then used an AI model to mine the results for overlooked drug targets for psoriasis.
 
   Nine gut bacteria linked to future type 2 diabetes riskNine gut bacteria linked to future type 2 diabetes risk
 
Research identifies specific gut microbes associated with future type 2 diabetes risk, emphasizing the impact of dietary fiber on microbiome health.
 
 Highly-sensitive blood test detects hidden traces of pancreatic cancer
 
Highly-sensitive blood test detects hidden traces of pancreatic cancerNorthwestern Medicine scientists have demonstrated that a highly sensitive blood test can detect traces of pancreatic cancer missed by standard testing, potentially helping physicians identify patients whose disease is more likely to return even when scans appear reassuring.
 
 
 Imaging scans detect prostate cancer progression despite stable PSA levels
 
Imaging scans detect prostate cancer progression despite stable PSA levelsPatients with advanced prostate cancer may need periodic imaging scans to catch tumor growth even with stable levels of prostate-specific antigen (PSA), a protein in the blood that doctors routinely monitor for cancer progression, according to an analysis led by researchers at Weill Cornell Medicine and Duke University.
 
 
 Gut immune cells help prevent severe salmonella infections
 
Gut immune cells help prevent severe salmonella infectionsWidely recognized as the face of food poisoning, salmonella bacteria lurk in raw meat and poultry, on pets and in unpasteurized dairy products.
 
 
 Persistent high cortisol levels increase hypertension risk in patients with adrenal tumors
 
Persistent high cortisol levels increase hypertension risk in patients with adrenal tumorsA major new study, published today in The Lancet Diabetes & Endocrinology has shown that cortisol levels in patients with adrenal tumours are far less stable than previously assumed.
 
 
 Allergies show a small but significant link to later cancer risk
 
Allergies show a small but significant link to later cancer riskA systematic review and meta-analysis of 28 cohort-based studies found a weak but statistically significant association between allergic diseases and later cancer incidence. The signal was strongest in the Western Pacific region and among people with asthma, but high heterogeneity and limited subgroup evidence mean the findings require caution.
 
 
 Some statins may increase erectile dysfunction risk
 
Some statins may increase erectile dysfunction riskResearch indicates that certain statins, particularly atorvastatin and simvastatin, may elevate the risk of erectile dysfunction, impacting men's health.
 
 
 New consensus outlines best practices for obesity medications
 
New consensus outlines best practices for obesity medicationsObesity and dietitian societies have joined forces to issue a new consensus statement on recommendations surrounding use of obesity drugs for weight loss treatment.
 
 
 Breaking up long periods of sitting is linked to lower cancer risk
 
Breaking up long periods of sitting is linked to lower cancer riskThe study highlights that how sedentary time is accumulated affects cancer risk, with prolonged sitting linked to higher risk and activity offering protection.
 
 
 New EV-SELEX strategy accelerates drug discovery for wide range of GPCRs
 
New EV-SELEX strategy accelerates drug discovery for wide range of GPCRsG protein-coupled receptors (GPCRs) are the most abundantly expressed proteins in the human body, which regulate diverse physiological processes ranging from pain perception to hormone signaling.
 
 
 Feeder-free TIL expansion system makes advanced cancer immunotherapy safer
 
Feeder-free TIL expansion system makes advanced cancer immunotherapy saferConventional TIL therapy, clinically validatedrecently with the U.S. Food and Drug Administration approval of lifileucel for advanced melanoma,stillfaces substantial hurdles.
 
 
 Analysis shows artificial sweeteners may harm adult metabolism function
 
Since the first introduction of saccharin, an array of artificial and other non-nutritive (i.e., low-calorie or calorie-free) sweeteners have become ubiquitous in the US food supply.
 
 
 Scientists map how chronic stress alters somatostatin levels in the brain
 
Consider the brake. Not the engine, which gets all the attention, but the brake, the quiet thing that decides how fast a system is allowed to go.
 
 
 New stem cell approach targets functional cure for diabetes
 
New research presented today at the International Society for Stem Cell Research (ISSCR) 2026 Annual Meeting explores an approach that could expand the potential of cell replacement therapy for type 1 diabetes by evaluating whether immune-engineered, allogeneic insulin-producing cells can survive and function without chronic immunosuppression.
 
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