Long-term omeprazole use linked to mineral imbalance risks

	Hematology
	The latest hematology news from News Medical

	Long-term omeprazole use linked to mineral imbalance risks A study conducted in Brazil by researchers at the Federal University of São Paulo (UNIFESP) and the ABC Medical School (FMABC) warns that the prolonged use of proton pump inhibitors (PPIs) can impair nutrient absorption.

	Hormonal contraceptives show differing heart risks among stressed women Antonia Seligowski, PhD, of the Neurocardiac Effects of Stress & Trauma Laboratory within the Department of Psychiatry at Mass General Brigham, is the senior author of a paper published in JAMA Network Open, "Hormonal contraceptive use, stress disorders, and cardiovascular and thrombotic risk in women."

			FDA label update expands CAR T access for primary CNS lymphoma Dana-Farber Cancer Institute-led research helped drive an FDA label update for axicabtagene ciloleucel (Yescarta) that removes a prior exclusion for patients with primary central nervous system lymphoma, a rare and aggressive lymphoma of the brain and spinal cord.

			Blocking p300 restores chemotherapy sensitivity in resistant tumors Overcoming tumor resistance to chemotherapy drugs has long been a challenge for oncology clinicians and researchers.

			Cellares to expand automated manufacturing to gene-edited stem cell therapies Cellares, the first Integrated Development and Manufacturing Organization (IDMO), today announced a collaboration with the Stanford Center for Definitive and Curative Medicine (CDCM) and Stanford Innovative Medicines Accelerator (IMA) to automate manufacturing and release testing for gene-edited hematopoietic stem cell (HSC) therapies, expanding the application of Cellares' automation platforms beyond T cell therapies into a new cell modality.

	Single-cell atlas reveals how melanoma evades the immune system Integrative analysis of immune ecotypes in skin cancers highlights metabolic reprogramming and macrophage polarization as key factors in melanoma progression.

	Parvovirus infection disrupts nucleolar structure and cellular balance Research at the University of Jyväskylä (Finland) reveals that autonomous parvoviruses, such as canine parvovirus, are highly capable of affecting the internal balance of the nucleolus.

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