Study links cannabis use to genotoxicity and transgenerational health impacts
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 Thrombotic thrombocytopenic purpura cases after CoronaVac raise concerns over vaccine safetyThrombotic thrombocytopenic purpura cases after CoronaVac raise concerns over vaccine safety
 
The COVID-19 pandemic has prompted the rapid development and administration of various vaccines worldwide, with some reports linking these vaccines to immune thrombotic thrombocytopenic purpura (TTP).
 
 
 Study links cannabis use to genotoxicity and transgenerational health impactsStudy links cannabis use to genotoxicity and transgenerational health impacts
 
Cannabis exposure leads to genetic damage and accelerated aging, raising concerns about its transgenerational health effects and public health implications.
 
   Gene editing with CRISPR may introduce new defectsGene editing with CRISPR may introduce new defects
 
The CRISPR tool is capable of repairing the genetic defect responsible for the immune disease chronic granulomatous disease.
 
   CAR T cell therapy breakthroughs bring new hope for treating solid tumorsCAR T cell therapy breakthroughs bring new hope for treating solid tumors
 
Researchers advance CAR T cell therapy for solid tumors by innovating ways to overcome the unique barriers of solid tumor environments, with promising clinical results.
 
   CRISPR technology reveals essential noncoding RNAs in the human genomeCRISPR technology reveals essential noncoding RNAs in the human genome
 
Genes contain instructions for making proteins, and a central dogma of biology is that this information flows from DNA to RNA to proteins.
 
 Genetic diagnosis solves medical mystery for 30 undiagnosed patients
 
Genetic diagnosis solves medical mystery for 30 undiagnosed patientsAn international team of researchers has provided a genetic diagnosis for 30 individuals whose condition was undiagnosed for years despite extensive clinical or genetic testing.
 
 
 New guidelines emphasize non-surgical treatments for uterine fibroids
 
New guidelines emphasize non-surgical treatments for uterine fibroidsUterine fibroids are a common condition that affects up to 80% of women in their lifetime. Nearly half of those women will experience symptoms that affect their quality of life and fertility, including severe pain and anemia.
 
 
 Berry-flavored vapes impair lung immune response
 
Berry-flavored vapes impair lung immune responseAlterations in AM function following the exposure to berry-flavored e-cigarettes that lead to poor immune responses to pathogens and reduced host survival.
 
 
 MethylGPT unlocks DNA secrets for age and disease prediction
 
MethylGPT unlocks DNA secrets for age and disease predictionResearchers developed MethylGPT, a powerful transformer-based model that identifies DNA methylation patterns, enabling advanced age and disease prediction with clinical potential.
 
 
 Revolutionary AI predicts aging and disease from DNA patterns
 
Revolutionary AI predicts aging and disease from DNA patternsResearchers developed CpGPT, a novel foundation model for DNA methylation analysis that captures sequence, positional, and epigenetic context to predict aging and disease risks. This model offers breakthroughs in imputing missing data and improving mortality and morbidity predictions.
 
 
 Engineered virus-like particles evolve for superior gene delivery efficiency
 
Engineered virus-like particles evolve for superior gene delivery efficiencyResearchers developed a barcoded directed evolution system for engineered virus-like particles (eVLPs), creating a fifth-generation (v5) eVLP with enhanced production, transduction, and gene-editing efficiency. This system could pave the way for improved gene delivery vehicles in therapeutic applications.
 
 
 New calculator predicts epilepsy risk after venous stroke
 
New calculator predicts epilepsy risk after venous strokeA practical calculator that predicts the risk of epilepsy after venous stroke is presented in a study from the University of Gothenburg and others. The aim is to improve care for those affected, which are predominantly young adults.
 
 
 Phase 2 study evaluates safety and efficacy of asunercept in COVID-19 patients
 
Phase 2 study evaluates safety and efficacy of asunercept in COVID-19 patientsThe ASUNCTIS trial evaluated asunercept's safety and efficacy in COVID-19, showing trends toward faster recovery despite not meeting statistical significance.
 
 
 MD Anderson launches new institute for advancing cell therapy
 
MD Anderson launches new institute for advancing cell therapyThe University of Texas MD Anderson Cancer Center today announced the launch of its Institute for Cell Therapy Discovery & Innovation, which will build upon longstanding MD Anderson clinical and research expertise to lead the world in developing and advancing impactful cell therapies for patients in need.
 
 
 NSAIDs raise bleeding risk in patients taking blood thinners
 
NSAIDs raise bleeding risk in patients taking blood thinnersPeople who take an anticoagulant medicine double their risk of an internal bleed if they take a type of painkiller called a non-steroidal anti-inflammatory drug (NSAID) such as ibuprofen, diclofenac or naproxen, according to research published in the European Heart Journal [1] today (Monday).
 
 
 FasL inhibitor speeds recovery and reduces mortality in severe COVID-19 patients
 
FasL inhibitor speeds recovery and reduces mortality in severe COVID-19 patientsA new clinical study shows that an inhibitor of Fas ligand (FasL), also called CD95 ligand (CD95L), led to a faster recovery of COVID-19 patients and reduced mortality.
 
 
 Memories of obesity can linger in fat cells long after weight loss
 
Memories of obesity can linger in fat cells long after weight lossEpigenetic changes from obesity persist after weight loss, altering fat cell function and increasing the risk of weight regain, impacting metabolic health.
 
 
 Common heart failure drug reduces risk of chemotherapy-induced heart damage in cancer patients
 
Common heart failure drug reduces risk of chemotherapy-induced heart damage in cancer patientsA commonly prescribed medication for heart failure was linked to a lower risk of heart damage, or cardiotoxicity, among high-risk cancer patients undergoing chemotherapy treatment using anthracyclines, according to preliminary late-breaking science presented today at the American Heart Association's Scientific Sessions 2024.
 
 
 New discovery could lead to better treatments for drug-resistant leukemia
 
New discovery could lead to better treatments for drug-resistant leukemiaScientists from Duke-NUS Medical School and their collaborators have identified an inherited genetic variation prevalent among East Asians that contributes to drug resistance, driving the aggressive growth of cancer cells in patients with chronic myeloid leukemia.
 
 
 Advances in neutropenia research could pave the way for better treatments
 
Advances in neutropenia research could pave the way for better treatmentsNeutropenia is a condition in which there are not enough neutrophils, a type of white blood cell, in the blood.