Gene therapy targeting connexin 43 shows promise across inherited heart diseases
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 Nearly half of adults now live with heart disease as obesity and diabetes surgeNearly half of adults now live with heart disease as obesity and diabetes surge
 
The 2026 American Heart Association Heart Disease and Stroke Statistics report shows that nearly half of adults are living with cardiovascular disease, with cardiometabolic risk factors projected to rise substantially by 2050. Despite progress in smoking reduction and cholesterol control, worsening obesity, diabetes, hypertension, sleep health, and persistent inequities threaten future cardiovascular health.
 
 
 Gene therapy targeting connexin 43 shows promise across inherited heart diseasesGene therapy targeting connexin 43 shows promise across inherited heart diseases
 
University of California San Diego-led team has discovered that restoring a key cardiac protein called connexin‑43 in a mouse model can dramatically improve heart function and extend survival in several inherited forms of arrhythmogenic cardiomyopathy (ACM)
 
 
 TGM2 as a novel biomarker for acute myocardial infarction and prognosis in acute coronary syndromeTGM2 as a novel biomarker for acute myocardial infarction and prognosis in acute coronary syndrome
 
Announcing a new article publication for Cardiovascular Innovations and Applications journal. Transglutaminase 2 (TGM2) has been implicated in various health conditions, yet its role in acute coronary syndrome (ACS) remains poorly characterized in clinical settings.
 
   What TV gets wrong about cardiac arrest and CPRWhat TV gets wrong about cardiac arrest and CPR
 
Inaccurate TV portrayals of cardiac arrest and CPR could affect viewer perceptions and actions, emphasizing the need for alignment with current guidelines.
 
   Smartwatches improve the detection of atrial fibrillationSmartwatches improve the detection of atrial fibrillation
 
Smartwatches with both PPG and ECG functionality improve the detection of atrial fibrillation in comparison with standard care.
 
 Scientists discover a non-classical platelet mechanism linked to severe infections
 
Scientists discover a non-classical platelet mechanism linked to severe infectionsPlatelets are small, anucleate blood cells that play an essential role in hemostasis. Their primary task is to recognize vascular injury, become activated, and aggregate via their surface receptor integrin αIIbβ3. This leads to the formation of a stable platelet plug that seals the wound and stops bleeding.
 
 
 Leading cardiovascular societies call for urgent action to address environmental stressors
 
Leading cardiovascular societies call for urgent action to address environmental stressorsThe world's leading cardiovascular societies, the European Society of Cardiology (ESC), the American College of Cardiology (ACC), the American Heart Association and the World Heart Federation (WHF) have today issued the first ever joint statement calling for urgent action to address environmental stressors as major, yet preventable, causes of cardiovascular disease (CVD).
 
 
 Why the age you start smoking matters as much as how much you smoke
 
Why the age you start smoking matters as much as how much you smokeStarting smoking at a younger age is associated with substantially higher risks of myocardial infarction, stroke, and death, even after accounting for cumulative smoking exposure. Early initiation also amplifies the cardiovascular harm of heavier smoking, indicating increased vulnerability when smoking begins in adolescence.
 
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